(Q30443511)

21 June 2017

1 reference

title

Voltage-gated Na+ channels in neuropathic pain (English)

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21 June 2017

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Nicholas James Hargus

series ordinal

1

1 reference

21 June 2017

Manoj Kumar Patel

series ordinal

2

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21 June 2017

language of work or name

English

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publication date

1 May 2007

1 reference

Expert Opinion on Investigational Drugs

21 June 2017

published in

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21 June 2017

volume

16

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21 June 2017

issue

5

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21 June 2017

page(s)

635-646

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

21 June 2017

1 reference

Neuropathic pain: aetiology, symptoms, mechanisms, and management

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Voltage-gated sodium channels and hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Phenotype and function of somatic primary afferent nociceptive neurones with C-, Adelta- or Aalpha/beta-fibres

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

B1 and TRPV-1 receptor genes and their relationship to hyperalgesia following spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Alteration of dorsal root ganglion P2X3 receptor expression and function following spinal nerve ligation in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

An acid sensing ion channel (ASIC) localizes to small primary afferent neurons in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Central sensitization and LTP: do pain and memory share similar mechanisms?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

The role of sodium channels in chronic inflammatory and neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Modulation of Na(v)1.5 by beta1-- and beta3-subunit co-expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Functional roles of the extracellular segments of the sodium channel alpha subunit in voltage-dependent gating and modulation by beta1 subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Nomenclature of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Molecular basis of charge movement in voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Calcium channel characteristics conferred on the sodium channel by single mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Differential involvement of spinal protein kinase C and protein kinase A in neuropathic and inflammatory pain in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Resurgence of sodium channel research

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Contributions of charged residues in a cytoplasmic linking region to Na channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

A mutation in segment IVS6 disrupts fast inactivation of sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

A critical role for the S4-S5 intracellular loop in domain IV of the sodium channel alpha-subunit in fast inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Negatively charged residues adjacent to IFM motif in the DIII–DIV linker of hNaV1.4 differentially affect slow inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Sodium channel inactivation: molecular determinants and modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Residue-specific effects on slow inactivation at V787 in D2-S6 of Na(v)1.4 sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Neuromodulation of Na+ channel slow inactivation via cAMP-dependent protein kinase and protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

The neurobiology of antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Interactions of local anesthetics with voltage-gated Na+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Neurobiology of neuropathic pain: mode of action of anticonvulsants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

21 January 2018

Sodium channels and pain

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Sodium channels, excitability of primary sensory neurons, and the molecular basis of pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Down-regulation of transcripts for Na channel alpha-SNS in spinal sensory neurons following axotomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

The changes in expression of three subtypes of TTX sensitive sodium channels in sensory neurons after spinal nerve ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Relationship between sodium channel NaV1.3 expression and neuropathic pain behavior in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

A novel tetrodotoxin-sensitive, voltage-gated sodium channel expressed in rat and human dorsal root ganglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

An SCN9A channelopathy causes congenital inability to experience pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Changes in Na(+) channel currents of rat dorsal root ganglion neurons following axotomy and axotomy-induced autotomy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

The pattern of expression of the voltage-gated sodium channels Na(v)1.8 and Na(v)1.9 does not change in uninjured primary sensory neurons in experimental neuropathic pain models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

A comparison of the potential role of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Contribution of the tetrodotoxin-resistant voltage-gated sodium channel NaV1.9 to sensory transmission and nociceptive behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Reversal of neuropathic pain by alpha-hydroxyphenylamide: a novel sodium channel antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Pharmacology of 2-[4-(4-chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide: a potent, broad-spectrum state-dependent sodium channel blocker for treating pain states.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

A pharmacophore derived phenytoin analogue with increased affinity for slow inactivated sodium channels exhibits a desired anticonvulsant profile

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Anticonvulsants (antineuropathics) for neuropathic pain syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Use of anticonvulsants for treatment of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Anticonvulsants for neuropathic pain syndromes: mechanisms of action and place in therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Double-blind randomized trial of tramadol for the treatment of the pain of diabetic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

A placebo-controlled trial of lamotrigine for painful HIV-associated neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Lamotrigine for central poststroke pain: a randomized controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Topiramate vs placebo in painful diabetic neuropathy: analgesic and metabolic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Topiramate in chronic lumbar radicular pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Topiramate in trigeminal neuralgia: a randomized, placebo-controlled multiple crossover pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Anti-allodynic effect of NW-1029, a novel Na(+) channel blocker, in experimental animal models of inflammatory and neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

The therapeutic potential of Na+ and Ca2+ channel blockers in pain management

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Prolonged duration local anesthesia from tetrodotoxin-enhanced local anesthetic microspheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

The effect of intravenous lidocaine on nociceptive processing in diabetic neuropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Mechanisms of action of carbamazepine and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Efficacy of oxcarbazepine in the treatment of painful diabetic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Tricyclic antidepressants as long-acting local anesthetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Effects of desipramine, amitriptyline, and fluoxetine on pain in diabetic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Depression masquerading as diabetic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Amitriptyline, but not lorazepam, relieves postherpetic neuralgia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Amitriptyline versus placebo in postherpetic neuralgia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Central post-stroke pain--a controlled trial of amitriptyline and carbamazepine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

Structural parts involved in activation and inactivation of the sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.16.5.635

10.1517/13543784.16.5.635

21 January 2018

Identifiers

DOI

1 reference

21 June 2017

1 reference