(Q30464012)

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Alpha 2-macroglobulin functions as a cytokine carrier to induce nitric oxide synthesis and cause nitric oxide-dependent cytotoxicity in the RAW 264.7 macrophage cell line

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Europe PubMed Central

PubMed publication ID

21 June 2017

Alpha 2-macroglobulin functions as a cytokine carrier to induce nitric oxide synthesis and cause nitric oxide-dependent cytotoxicity in the RAW 264.7 macrophage cell line (English)

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Europe PubMed Central

PubMed publication ID

21 June 2017

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author name string

Lysiak JJ

1

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Europe PubMed Central

PubMed publication ID

21 June 2017

Hussaini IM

2

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Europe PubMed Central

PubMed publication ID

21 June 2017

Webb DJ

3

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

Glass WF 2nd

4

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

Allietta M

5

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Europe PubMed Central

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21 June 2017

Gonias SL

6

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21 June 2017

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publication date

1 September 1995

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Europe PubMed Central

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21 June 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

21 June 2017

270

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Europe PubMed Central

PubMed publication ID

21 June 2017

37

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Europe PubMed Central

PubMed publication ID

21 June 2017

21919-21927

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Europe PubMed Central

PubMed publication ID

21 June 2017

Nitric oxide synthases: Roles, tolls, and controls

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

Calmodulin is a subunit of nitric oxide synthase from macrophages

1 reference

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21 January 2018

Nitric oxide: a cytotoxic activated macrophage effector molecule

1 reference

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Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells

1 reference

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21 January 2018

Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide

1 reference

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21 January 2018

Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin

1 reference

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21 January 2018

Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent and inhibited by arginine analogs with a rank-order of potency characteristic of activated macrophages

1 reference

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21 January 2018

Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells

1 reference

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21 January 2018

Induction and potential biological relevance of a Ca(2+)-independent nitric oxide synthase in the myocardium

1 reference

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21 January 2018

The promoter of the prostate-specific antigen gene contains a functional androgen responsive element

1 reference

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21 January 2018

Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease

1 reference

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21 January 2018

Cloning and characterization of inducible nitric oxide synthase from mouse macrophages

1 reference

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21 January 2018

Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide

1 reference

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21 January 2018

Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta

1 reference

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21 January 2018

Inhibition of cytokine‐induced nitric oxide production by transforming growth factor‐beta 1 in human smooth muscle cells

1 reference

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21 January 2018

1 reference

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21 January 2018

Nitric oxide mediates cytotoxicity and basic fibroblast growth factor release in cultured vascular smooth muscle cells. A possible mechanism of neovascularization in atherosclerotic plaques

1 reference

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21 January 2018

A protective role for nitric oxide in the oxidative modification of low density lipoproteins by mouse macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

p53 expression in nitric oxide‐induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

α2‐Macroglobulin A Multifunctional Binding and Targeting Protein with Possible Roles in Immunity and Autoimmunitya

1 reference

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21 January 2018

The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism

1 reference

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21 January 2018

α2‐Macroglobulin and the α2‐Macroglobulin Receptor/LRP A Growth Regulatory Axisa

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

Evidence for similar conformational changes in α2-macroglobulin on reaction with primary amines or proteolytic enzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

Physical properties of human alpha 2-macroglobulin following reaction with methylamine and trypsin

1 reference

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21 January 2018

The human alpha 2-macroglobulin receptor: identification of a 420-kD cell surface glycoprotein specific for the activated conformation of alpha 2-macroglobulin

1 reference

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21 January 2018

Neurotrophin binding to human alpha 2-macroglobulin under apparent equilibrium conditions

1 reference

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21 January 2018

Binding of transforming growth factor-beta 1 to methylamine-modified alpha 2-macroglobulin and to binary and ternary alpha 2-macroglobulin-proteinase complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

Receptor-recognized α2-macroglobulin-methylamine elevates intracellular calcium, inositol phosphates and cyclic AMP in murine peritoneal macrophages

1 reference

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21 January 2018

The structure of α2-macroglobulin-methylamine after papain digestion as determined by electron microscopy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

An alpha 2-macroglobulin receptor-dependent mechanism for the plasma clearance of transforming growth factor-beta 1 in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

Detection of DNA fragmentation in apoptosis: application of in situ nick translation to cell culture systems and tissue sections

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

Cell nucleus and DNA fragmentation are not required for apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

Expression and secretion of type beta transforming growth factor by activated human macrophages

1 reference

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21 January 2018

Deactivation of macrophages by transforming growth factor-β

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.37.21919

21 January 2018

Identifiers

10.1074/JBC.270.37.21919

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

ResearchGate publication ID

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