(Q30468797)

English

PDE4 inhibition enhances hippocampal synaptic plasticity in vivo and rescues MK801-induced impairment of long-term potentiation and object recognition memory in an animal model of psychosis

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22832854%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PDE4 inhibition enhances hippocampal synaptic plasticity in vivo and rescues MK801-induced impairment of long-term potentiation and object recognition memory in an animal model of psychosis (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22832854%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

based on heuristic

inferred from title

long-term potentiation

1 reference

based on heuristic

inferred from title

synaptic plasticity

1 reference

based on heuristic

inferred from title

Denise Manahan-Vaughan

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22832854%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

V Wiescholleck

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22832854%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

publication date

13 March 2012

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22832854%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Translational Psychiatry

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22832854%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22832854%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

e89

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22832854%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Cooperation between cholinergic and glutamatergic receptors are essential to induce BDNF-dependent long-lasting memory storage

1 reference

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20 June 2018

Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling

1 reference

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20 June 2018

Early intervention services, cognitive-behavioural therapy and family intervention in early psychosis: systematic review

1 reference

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20 June 2018

Testing the glutamate hypothesis of schizophrenia

1 reference

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20 June 2018

NMDA receptor phosphorylation at a site affected in schizophrenia controls synaptic and behavioral plasticity.

1 reference

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Neuroenhancement: status quo and perspectives

1 reference

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20 June 2018

Early intervention in psychosis: concepts, evidence and future directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Selective phosphodiesterase inhibitors: a promising target for cognition enhancement.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Antipsychotic-like properties of phosphodiesterase 4 inhibitors: evaluation of 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone (RO-20-1724) with auditory event-related potentials and prepulse inhibition of startle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia

1 reference

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20 June 2018

Early intervention in first episode psychosis: hope for a better future.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

The evolution of drug development in schizophrenia: past issues and future opportunities

1 reference

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20 June 2018

Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Role of DISC1 in neural development and schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Hippocampal long-term depression: master or minion in declarative memory processes?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Rolipram: a specific phosphodiesterase 4 inhibitor with potential antipsychotic activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Signaling from cAMP/PKA to MAPK and synaptic plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Effects of ketamine in normal and schizophrenic volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Early intervention in psychosis. The critical period hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Subtype-specific involvement of metabotropic glutamate receptors in two forms of long-term potentiation in the dentate gyrus of freely moving rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Glutamate pharmacology and the treatment of schizophrenia: current status and future directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

A synaptic model of memory: long-term potentiation in the hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Radioimmunoassay for cyclic nucleotides. I. Preparation of antibodies and iodinated cyclic nucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

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Multiple isozymes of cyclic nucleotide phosphodiesterase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

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Rolipram in major depressive disorder: results of a double-blind comparative study with imipramine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Femtomole sensitive radioimmunoassay for cyclic AMP and cyclic GMP after 2'0 acetylation by acetic anhydride in aqueous solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3309535

20 June 2018

Sub-chronic rolipram treatment leads to a persistent improvement in long-term object memory in rats.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

The effects of phosphodiesterase inhibition on cyclic GMP and cyclic AMP accumulation in the hippocampus of the rat.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

The type IV-specific phosphodiesterase inhibitor rolipram and its effect on hippocampal long-term potentiation and synaptic tagging.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

Outcome of common mental disorders in Harare, Zimbabwe.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

Acute and long-term effects of MK-801 on direct cortical input evoked homosynaptic and heterosynaptic plasticity in the CA1 region of the female rat.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

A single application of MK801 causes symptoms of acute psychosis, deficits in spatial memory, and impairment of synaptic plasticity in rats

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

Rescue of hippocampal LTP and learning deficits in a rat model of psychosis by inhibition of glycine transporter-1 (GlyT1).

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

Rolipram attenuates MK-801-induced deficits in latent inhibition

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

Antipsychotic profile of rolipram: efficacy in rats and reduced sensitivity in mice deficient in the phosphodiesterase-4B (PDE4B) enzyme.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

cGMP, but not cAMP, in rat hippocampus is involved in early stages of object memory consolidation

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

Mitogen-activated protein kinase-mediated reinforcement of hippocampal early long-term depression by the type IV-specific phosphodiesterase inhibitor rolipram and its effect on synaptic tagging.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

Subchronic rolipram delivery activates hippocampal CREB and arc, enhances retention and slows down extinction of conditioned fear.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

Activation of medial prefrontal cortex by phencyclidine is mediated via a hippocampo-prefrontal pathway

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

Protein kinase A regulates calcium permeability of NMDA receptors.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

Decreased phosphorylation of NMDA receptor type 1 at serine 897 in brains of patients with Schizophrenia.

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

Effects of the novel PDE4 inhibitors MEM1018 and MEM1091 on memory in the radial-arm maze and inhibitory avoidance tests in rats

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

Nonuniform probability of glutamate release at a hippocampal synapse

1 reference

https://api.crossref.org/works/10.1038%2FTP.2012.17

21 January 2018

Genetics. Two genes link two distinct psychoses

1 reference

https://pubmed.ncbi.nlm.nih.gov/22832854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of rolipram in the rhesus and cynomolgus monkeys, the rat and the rabbit. Studies on species differences

1 reference

https://pubmed.ncbi.nlm.nih.gov/22832854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/22832854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Therapeutic strategies in the first psychotic episode]

1 reference

https://pubmed.ncbi.nlm.nih.gov/22832854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of parvalbumin and glutamic acid decarboxylase-67 after acute administration of MK-801. Implications for the NMDA hypofunction model of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22832854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Results of a phase II study of the antidepressant effect of rolipram

1 reference

https://pubmed.ncbi.nlm.nih.gov/22832854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/TP.2012.17

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22832854%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Dimensions Publication ID

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22832854%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22832854%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

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