(Q30471061)

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Mitochondrial toxins in models of neurodegenerative diseases. I: In vivo brain hydroxyl radical production during systemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions

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Europe PubMed Central

21 June 2017

Mitochondrial toxins in models of neurodegenerative diseases. I: In vivo brain hydroxyl radical production during systemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions (English)

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Europe PubMed Central

21 June 2017

neurodegeneration

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based on heuristic

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Smith TS

1

1 reference

Europe PubMed Central

21 June 2017

Bennett JP Jr

2

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Europe PubMed Central

21 June 2017

language of work or name

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publication date

1 August 1997

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Europe PubMed Central

21 June 2017

number of pages

6

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Europe PubMed Central

21 June 2017

765

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Europe PubMed Central

21 June 2017

2

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Europe PubMed Central

21 June 2017

183-188

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Europe PubMed Central

21 June 2017

Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's disease

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Platelet mitochondrial function in Parkinson's disease. The Royal Kings and Queens Parkinson Disease Research Group

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Abnormalities of the electron transport chain in idiopathic Parkinson's disease

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Impaired oxidative decarboxylation of pyruvate in fibroblasts from patients with Parkinson's disease

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Respiratory chain abnormalities in skeletal muscle from patients with Parkinson's disease.

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Mitochondrial respiratory chain activity in skeletal muscle from patients with Parkinson's disease

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Mitochondrial complex I deficiency in Parkinson's disease

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Mitochondrial complex I deficiency in Parkinson's disease

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Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease

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Role of mitochondria in the etiology and pathogenesis of Parkinson's disease

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Cytochrome oxidase deficiency in Alzheimer's disease

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Brain Cytochrome Oxidase in Alzheimer's Disease

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7 January 2021

Electron transport chain defects in Alzheimer's disease brain.

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Reduced platelet cytochrome c oxidase activity in Alzheimer's disease.

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Expression of heme oxygenase-1 in the senescent and Alzheimer-diseased brain

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7 January 2021

Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.

1 reference

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7 January 2021

MPTP, MPP+ and mitochondrial function

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Inhibition of mitochondrial respiration by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mouse brain in vivo

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MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease

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Origin and functional consequences of the complex I defect in Parkinson's disease

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7 January 2021

Altered calcium homeostasis in cells transformed by mitochondria from individuals with Parkinson's disease

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In vivo trapping of hydroxyl free radicals in the striatum utilizing intracranial microdialysis perfusion of salicylate: effects of MPTP, MPDP+, and MPP+

1 reference

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7 January 2021

Reduction of MPP(+)-induced hydroxyl radical formation and nigrostriatal MPTP toxicity by inhibiting nitric oxide synthase.

1 reference

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7 January 2021

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

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7 January 2021

Spin trapping of azidyl and hydroxyl radicals in azide-inhibited rat brain submitochondrial particles.

1 reference

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7 January 2021

Cytochrome Oxidase Inhibition: A Novel Animal Model of Alzheimer's Disease

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7 January 2021

Synergy between chronic corticosterone and sodium azide treatments in producing a spatial learning deficit and inhibiting cytochrome oxidase activity

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7 January 2021

Dopamine transporter mutants selectively enhance MPP+ transport

1 reference

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7 January 2021

Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2897%2900429-0

7 January 2021

Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic study

1 reference

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7 January 2021

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

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7 January 2021

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

1 reference

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7 January 2021

Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice.

1 reference

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7 January 2021

1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles

1 reference

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7 January 2021

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

1 reference

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7 January 2021

Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes

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7 January 2021

Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture

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The non-competitive NMDA-receptor antagonist MK-801 prevents the massive release of glutamate and aspartate from rat striatum induced by 1-methyl-4-phenylpyridinium (MPP+).

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Do NMDA receptor antagonists protect against MPTP-toxicity? Biochemical and immunocytochemical analyses in black mice

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Blockade of 1-methyl-4-phenylpyridinium ion (MPP+) nigral toxicity in the rat by prior decortication or MK-801 treatment: a stereological estimate of neuronal loss.

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Partial protective effect of MK-801 on MPTP-induced reduction of striatal dopamine in mice

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10.1016/S0006-8993(97)00429-0

1 reference

Europe PubMed Central

21 June 2017

1 reference

Europe PubMed Central

21 June 2017

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