(Q30480596)

12 August 2017

Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1). (English)

1 reference

12 August 2017

1 reference

Jamie M Keck

1

1 reference

12 August 2017

Matthew K Summers

2

1 reference

12 August 2017

Donato Tedesco

3

1 reference

12 August 2017

Susanna Ekholm-Reed

4

1 reference

12 August 2017

Li-Chiou Chuang

5

1 reference

12 August 2017

Peter K Jackson

6

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12 August 2017

Steven I Reed

7

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12 August 2017

language of work or name

English

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publication date

1 July 2007

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12 August 2017

Journal of Cell Biology

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12 August 2017

178

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12 August 2017

371-385

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12 August 2017

3

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describes a project that uses

12 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2064850/fullTextXML

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2064850/fullTextXML

inferred from PubMed Central ID database lookup

cites work

CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Mutual inhibition of separase and Cdk1 by two-step complex formation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Deregulation of cyclin E in human cells interferes with prereplication complex assembly

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Inactivation of hCDC4 can cause chromosomal instability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Cyclin E ablation in the mouse

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Abnormal expression pattern of cyclin E in tumour cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Cyclin E and survival in patients with breast cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Regulation of human separase by securin binding and autocleavage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

hCDC4 gene mutations in endometrial cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Cohesin cleavage by separase required for anaphase and cytokinesis in human cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Prognostic implications of p27 and cyclin E protein contents in malignant lymphomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Mechanisms underlying losses of heterozygosity in human colorectal cancers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

APC(ste9/srw1) promotes degradation of mitotic cyclins in G(1) and is inhibited by cdc2 phosphorylation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Destruction of the securin Pds1p occurs at the onset of anaphase during both meiotic divisions in yeast

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Mitotic regulation of the APC activator proteins CDC20 and CDH1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Cdk2-dependent and -independent pathways in E2F-mediated S phase induction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Deregulated cyclin E induces chromosome instability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

The role of cyclin E in the regulation of entry into S phase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Cyclin-dependent regulation of G1 in mammalian fibroblasts.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B and B3

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Cyclins as markers of tumor proliferation: immunocytochemical studies in breast cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064850

Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle

28 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200703202

Cyclin E dysregulation and chromosomal instability in endometrial cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200703202

The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200703202

Securin associates with APCCdh1 in prometaphase but its destruction is delayed by Rae1 and Nup98 until the metaphase/anaphase transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200703202

Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200703202

Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200703202

Cyclin E expression and proliferation in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200703202

Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200703202

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200703202

CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200703202

Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200703202

Association of human cyclin E with a periodic G1-S phase protein kinase

21 January 2018

1 reference

12 December 2020

Regulated separation of sister centromeres depends on the spindle assembly checkpoint but not on the anaphase promoting complex/cyclosome

1 reference

12 December 2020

Deregulated cyclin E promotes p53 loss of heterozygosity and tumorigenesis in the mouse mammary gland

1 reference

12 December 2020

Deregulation of the cell cycle in cancer

1 reference

12 December 2020

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

1 reference

12 December 2020

Cyclin E-induced S phase without activation of the pRb/E2F pathway.

1 reference

12 December 2020

Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition

1 reference

12 December 2020

Genetic interactions between Cdk1-CyclinB and the Separase complex in Drosophila

1 reference

12 December 2020

Separase is required at multiple pre-anaphase cell cycle stages in human cells

1 reference

12 December 2020

Deregulation of cyclin E in breast cancer

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200703202

1 reference

12 August 2017

1 reference

12 August 2017

1 reference