(Q30489417)

English

Temporal and mutation-specific alterations in Ca2+ homeostasis differentially determine the progression of cTnT-related cardiomyopathies in murine models

scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Temporal and mutation-specific alterations in Ca2+ homeostasis differentially determine the progression of cTnT-related cardiomyopathies in murine models (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1 reference

based on heuristic

inferred from title

author name string

Pia J Guinto

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Todd E Haim

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Candice C Dowell-Martino

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Nathaniel Sibinga

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Jil C Tardiff

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

publication date

5 June 2009

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

American Journal of Physiology Heart and Circulatory Physiology

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

297

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

H614-26

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2724218/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Aerobic interval training enhances cardiomyocyte contractility and Ca2+ cycling by phosphorylation of CaMKII and Thr-17 of phospholamban

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Long-term follow-up of R403WMYH7 and R92WTNNT2 HCM families: mutations determine left ventricular dimensions but not wall thickness during disease progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Reversal of calcium cycling defects in advanced heart failure toward molecular therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Calmodulin kinase signaling in heart: an intriguing candidate target for therapy of myocardial dysfunction and arrhythmias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Regulation of cardiac contractile function by troponin I phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Role of troponin T in disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Sarcoplasmic reticulum Ca-ATPase-phospholamban interactions and dilated cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Targeted Inhibition of Ca2+/Calmodulin-dependent Protein Kinase II in Cardiac Longitudinal Sarcoplasmic Reticulum Results in Decreased Phospholamban Phosphorylation at Threonine 17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Chronic SR Ca2+-ATPase inhibition causes adaptive changes in cellular Ca2+ transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Molecular mechanisms of inherited cardiomyopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

The troponin tail domain promotes a conformational state of the thin filament that suppresses myosin activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

From the sarcomere to the nucleus: role of genetics and signaling in structural heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Transgenic incorporation of skeletal TnT into cardiac myofilaments blunts PKC-mediated depression of force

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Ca(2+) activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Survival after cardiac arrest or sustained ventricular tachycardia in patients with hypertrophic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Roles for the troponin tail domain in thin filament assembly and regulation. A deletional study of cardiac troponin T.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Sudden death due to troponin T mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Codon 102 of the cardiac troponin T gene is a putative hot spot for mutations in familial hypertrophic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Cardiac-specific overexpression of phospholamban alters calcium kinetics and resultant cardiomyocyte mechanics in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Familial hypertrophic cardiomyopathy: a genetic model of cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724218

20 June 2018

Sarcoplasmic reticulum Ca2+ and heart failure: roles of diastolic leak and Ca2+ transport

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01143.2008

21 January 2018

Increase in tension-dependent ATP consumption induced by cardiac troponin T mutation

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01143.2008

21 January 2018

Parvalbumin corrects slowed relaxation in adult cardiac myocytes expressing hypertrophic cardiomyopathy-linked alpha-tropomyosin mutations

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01143.2008

21 January 2018

Computational Characterization of Mutations in Cardiac Troponin T Known to Cause Familial Hypertrophic Cardiomyopathy

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01143.2008

21 January 2018

Effects of selective matrix metalloproteinase inhibitor (PG-116800) to prevent ventricular remodeling after myocardial infarction: results of the PREMIER (Prevention of Myocardial Infarction Early Remodeling) trial.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01143.2008

21 January 2018

Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01143.2008

21 January 2018

Targeted inhibition of sarcoplasmic reticulum CaMKII activity results in alterations of Ca2+ homeostasis and cardiac contractility

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01143.2008

21 January 2018

Familial hypertrophic cardiomyopathy-linked mutant troponin T causes stress-induced ventricular tachycardia and Ca2+-dependent action potential remodeling.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01143.2008

21 January 2018

Pharmacological inhibition of na/ca exchange results in increased cellular Ca2+ load attributable to the predominance of forward mode block.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01143.2008

21 January 2018

Troponin T and beta-myosin mutations have distinct cardiac functional effects in hypertrophic cardiomyopathy patients without hypertrophy

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01143.2008

21 January 2018

Unloaded shortening increases peak of Ca2+ transients but accelerates their decay in rat single cardiac myocytes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01143.2008

21 January 2018

Altered hemodynamics in transgenic mice harboring mutant tropomyosin linked to hypertrophic cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent FHC-related cardiac troponin T mutations exhibit specific alterations in myocellular contractility and calcium kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beyond beta blockers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial hypertrophic cardiomyopathy mutations from different functional regions of troponin T result in different effects on the pH and Ca2+ sensitivity of cardiac muscle contraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased functional importance of the Na,Ca-exchanger in contracting failing human myocardium but unchanged activity in isolated vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of the immunoblot technique for quantitation of protein levels in cardiac homogenates

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gender influences on sarcoplasmic reticulum Ca2+-handling in failing human myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calmodulin kinase II inhibition protects against structural heart disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional implications of the phospholamban hinge domain: impaired SR Ca2+ uptake as a primary cause of heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folding and function of the troponin tail domain. Effects of cardiomyopathic troponin T mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts--role of myofilament Ca2+ sensitivity increase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional consequences of troponin T mutations found in hypertrophic cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased contractility and altered Ca(2+) transients of mouse heart myocytes conditionally expressing PKCbeta

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of sarcoplasmic reticulum Ca2+ transport and Ca2+ ATPase enzymatic properties using mouse cardiac tissue homogenates

1 reference

https://pubmed.ncbi.nlm.nih.gov/19502551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPHEART.01143.2008

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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