(Q30492592)

19 October 2017

Cardiac and vascular functions of the zebrafish orthologues of the type I neurofibromatosis gene NFI. (English)

1 reference

19 October 2017

1 reference

GOA release 2020-03-11

author name string

Arun Padmanabhan

1

1 reference

19 October 2017

Jeong-Soo Lee

2

1 reference

19 October 2017

Fraz A Ismat

3

1 reference

19 October 2017

Min Min Lu

4

1 reference

19 October 2017

Nathan D Lawson

5

1 reference

19 October 2017

John P Kanki

6

1 reference

19 October 2017

A Thomas Look

7

1 reference

19 October 2017

Jonathan A Epstein

8

1 reference

19 October 2017

language of work or name

English

0 references

publication date

4 December 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 October 2017

1 reference

19 October 2017

106

1 reference

19 October 2017

52

1 reference

19 October 2017

22305-22310

1 reference

Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

K-ras/PI3K-Akt signaling is essential for zebrafish hematopoiesis and angiogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Cerebrovascular dysplasia in neurofibromatosis type 1.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

H-ras regulates angiogenesis and vascular permeability by activation of distinct downstream effectors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Induction of abnormal proliferation by nonmyelinating schwann cells triggers neurofibroma formation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

p53 activation by knockdown technologies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Tumor microenvironment and neurofibromatosis type I: connecting the GAPs

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Guidelines for the diagnosis and management of individuals with neurofibromatosis 1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Global analysis of hematopoietic and vascular endothelial gene expression by tissue specific microarray profiling in zebrafish

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Semaphorin-plexin signaling guides patterning of the developing vasculature.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Development gone awry: congenital heart disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Capillary malformation-arteriovenous malformation, a new clinical and genetic disorder caused by RASA1 mutations

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Nf1 has an essential role in endothelial cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Genetics of neurofibromatosis 1 and the NF1 gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Cardiovascular disease in neurofibromatosis 1: report of the NF1 Cardiovascular Task Force

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Neurofibromas in NF1: Schwann cell origin and role of tumor environment

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Neurofibromin regulates G protein-stimulated adenylyl cyclase activity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Studying vascular development in the zebrafish

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Bipartite interaction between neurofibromatosis type I protein (neurofibromin) and syndecan transmembrane heparan sulfate proteoglycans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Learning deficits, but normal development and tumor predisposition, in mice lacking exon 23a of Nf1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

NF1 tumor suppressor gene function: narrowing the GAP

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Mouse tumor model for neurofibromatosis type 1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Mouse models of tumor development in neurofibromatosis type 1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Zebrafish hox clusters and vertebrate genome evolution

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Mutations in the GAP-related domain impair the ability of neurofibromin to associate with microtubules.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Rescue of a Drosophila NF1 mutant phenotype by protein kinase A.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

A mouse model for the learning and memory deficits associated with neurofibromatosis type I

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptides

14 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0901932106

Parkes Weber syndrome, vein of Galen aneurysmal malformation, and other fast-flow vascular anomalies are caused byRASA1 mutations

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0901932106

Epidermal growth factor receptor signaling pathways are associated with tumorigenesis in the Nf1:p53 mouse tumor model.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Mutations of the NF1 gene in children with juvenile myelomonocytic leukemia without clinical evidence of neurofibromatosis, type 1.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799742

Angiogenic network formation in the developing vertebrate trunk

26 November 2018

1 reference

12 December 2020

Tie2-Cre-induced inactivation of a conditional mutant Nf1 allele in mouse results in a myeloproliferative disorder that models juvenile myelomonocytic leukemia

1 reference

12 December 2020

Expression of the neurofibromatosis I gene product, neurofibromin, in blood vessel endothelial cells and smooth muscle

1 reference

12 December 2020

Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0901932106

1 reference

19 October 2017

0 references

1 reference

19 October 2017

PubMed publication ID

19966217

1 reference