(Q30494882)

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11beta-hydroxysteroid dehydrogenase type 1 expression is increased in the aged mouse hippocampus and parietal cortex and causes memory impairments

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Europe PubMed Central

PMC publication ID

26 September 2017

11beta-hydroxysteroid dehydrogenase type 1 expression is increased in the aged mouse hippocampus and parietal cortex and causes memory impairments (English)

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

1 reference

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author name string

Megan C Holmes

1

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

Roderick N Carter

2

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

June Noble

3

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

Shruti Chitnis

4

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

Amy Dutia

5

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

Janice M Paterson

6

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

John J Mullins

7

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

Jonathan R Seckl

8

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

Joyce L W Yau

9

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Europe PubMed Central

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26 September 2017

language of work or name

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publication date

1 May 2010

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Europe PubMed Central

PMC publication ID

26 September 2017

Journal of Neuroscience

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Europe PubMed Central

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26 September 2017

30

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Europe PubMed Central

PMC publication ID

26 September 2017

20

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

6916-6920

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

Role of the parietal cortex in long-term representation of spatial information in the rat.

1 reference

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20 June 2018

Rapid encoding of new information alters the profile of plasticity-related mRNA transcripts in the hippocampal CA3 region

1 reference

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20 June 2018

Selective effect of Apo e4 on CA3 and dentate in normal aging and Alzheimer's disease using high resolution MRI at 4 T.

1 reference

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20 June 2018

Cognitive and neuroinflammatory consequences of mild repeated stress are exacerbated in aged mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

11beta-HSD1, inflammation, metabolic disease and age-related cognitive (dys)function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Chronic glucocorticoids increase hippocampal vulnerability to neurotoxicity under conditions that produce CA3 dendritic retraction but fail to impair spatial recognition memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 as a promising therapeutic target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Physiology and neurobiology of stress and adaptation: central role of the brain

1 reference

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20 June 2018

Liver-selective transgene rescue of hypothalamic-pituitary-adrenal axis dysfunction in 11beta-hydroxysteroid dehydrogenase type 1-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

The role of 11beta-hydroxysteroid dehydrogenases in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

11Beta-hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Obese Zucker rats have reduced mineralocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type 1 expression in hippocampus-implications for dysregulation of the hypothalamic-pituitary-adrenal axis in obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Impaired retention of spatial memory after transection of longitudinally oriented axons of hippocampal CA3 pyramidal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Aging causes a preferential loss of cholinergic innervation of characterized neocortical pyramidal neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

A transgenic model of visceral obesity and the metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

The consolidation of new but not reactivated memory requires hippocampal C/EBPbeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Lack of tissue glucocorticoid reactivation in 11beta -hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Intracellular regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase (11beta-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis: analysis of 11beta-HSD-1-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Understanding the role of glucocorticoids in obesity: tissue-specific alterations of corticosterone metabolism in obese Zucker rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Corticosteroids, the Aging Brain and Cognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Cortisol levels during human aging predict hippocampal atrophy and memory deficits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Chronic stress impairs rat spatial memory on the Y maze, and this effect is blocked by tianeptine pretreatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Repeated stress causes reversible impairments of spatial memory performance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Individual differences in hypothalamic-pituitary-adrenal activity in later life and hippocampal aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Brain Aging Correlates: Retardation by Hormonal-Pharmacological Treatments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

20 June 2018

Enhanced hippocampal long-term potentiation and spatial learning in aged 11beta-hydroxysteroid dehydrogenase type 1 knock-out mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

26 November 2018

The mother or the fetus? 11beta-hydroxysteroid dehydrogenase type 2 null mice provide evidence for direct fetal programming of behavior by endogenous glucocorticoids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

26 November 2018

Dysregulation of memory-related proteins in the hippocampus of aged rats and their relation with cognitive impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

26 November 2018

Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

26 November 2018

Chronic treatment with the antidepressant amitriptyline prevents impairments in water maze learning in aging rats.

1 reference

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26 November 2018

Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

26 November 2018

Restraint stress-induced alterations in the levels of biogenic amines, amino acids, and AChE activity in the hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885438

26 November 2018

Discovery and biological evaluation of adamantyl amide 11β-HSD1 inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

11 beta-Hydroxysteroid dehydrogenase in cultured hippocampal cells reactivates inert 11-dehydrocorticosterone, potentiating neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cortisol metabolism in human obesity: impaired cortisone-->cortisol conversion in subjects with central adiposity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20484633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0731-10.2010

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

26 September 2017

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