(Q30497679)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Tomosyn inhibits synaptotagmin-1-mediated step of Ca2+-dependent neurotransmitter release through its N-terminal WD40 repeats (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

3

1 reference

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14 January 2020

Kohei Fujikura

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

author name string

Yasunori Yamamoto

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Sumiko Mochida

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Katsuhisa Kawai

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Takao Kurooka

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Kenji Iwasaki

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Toshiaki Sakisaka

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

language of work or name

English

0 references

publication date

26 October 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

14 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

volume

285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

issue

52

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

page(s)

40943-40955

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

The tail domain of tomosyn controls membrane fusion through tomosyn displacement by VAMP2.

14 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Synaptotagmin-mediated bending of the target membrane is a critical step in Ca(2+)-regulated fusion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Friends and foes in synaptic transmission: the role of tomosyn in vesicle priming

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Reciprocal intramolecular interactions of tomosyn control its inhibitory activity on SNARE complex formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

The Janus-faced nature of the C(2)B domain is fundamental for synaptotagmin-1 function.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

20 June 2018

Synaptic vesicle fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

How does synaptotagmin trigger neurotransmitter release?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

How synaptotagmin promotes membrane fusion.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Molecular anatomy of a trafficking organelle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

SNAREs--engines for membrane fusion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

PKA-catalyzed phosphorylation of tomosyn and its implication in Ca2+-dependent exocytosis of neurotransmitter

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

20 June 2018

Synaptic vesicle pools

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Structural basis for the inhibitory role of tomosyn in exocytosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

The synaptic vesicle cycle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Subtype-selective reconstitution of synaptic transmission in sympathetic ganglion neurons by expression of exogenous calcium channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Sr2+ binding to the Ca2+ binding site of the synaptotagmin 1 C2B domain triggers fast exocytosis without stimulating SNARE interactions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Estimation of quantal parameters at the calyx of Held synapse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Visualizing recycling synaptic vesicles in hippocampal neurons by FM 1-43 photoconversion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Limited numbers of recycling vesicles in small CNS nerve terminals: implications for neural signaling and vesicular cycling.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

How does calcium trigger neurotransmitter release?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Synaptotagmin I functions as a calcium regulator of release probability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

The synaptic vesicle cycle revisited

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

SNAREpins: minimal machinery for membrane fusion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Evidence for cholinergic synapses between dissociated rat sympathetic neurons in cell culture

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Morphological and cytochemical studies of synapses formed in culture between isolated rat superior cervical ganglion neurons.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Localization and subcellular distribution of cellular ras gene products in rat brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Postnatal rat sympathetic neurons in culture. II. Synaptic transmission by postnatal neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Studies on rat sympathetic neurons developing in cell culture. III. Cholinergic transmission

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Synaptic transmission between rat superior cervical ganglion neurons in dissociated cell cultures

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Synaptic transmission between rat spinal cord explants and dissociated superior cervical ganglion neurons in tissue culture

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Synaptic vesicle cytochemistry changes when cultured sympathetic neurones develop cholinergic interactions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Morphological correlates of functionally defined synaptic vesicle populations

20 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.156893

The structural organization of the readily releasable pool of synaptic vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.156893

Synaptotagmin I functions as a calcium sensor to synchronize neurotransmitter release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.156893

Dual roles of the C2B domain of synaptotagmin I in synchronizing Ca2+-dependent neurotransmitter release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.156893

Antagonistic regulation of synaptic vesicle priming by Tomosyn and UNC-13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.156893

Multiple functional domains are involved in tomosyn regulation of exocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.156893

A cholinergic model synapse to elucidate protein function at presynaptic terminals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.156893

The R-SNARE Motif of Tomosyn Forms SNARE Core Complexes with Syntaxin 1 and SNAP-25 and Down-regulates Exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.156893

Two modes of vesicle recycling in the rat calyx of Held.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003394

Analysis of the mechanism for acetylcholine release at the synapse formed between rat sympathetic neurons in culture

26 November 2018

1 reference

12 December 2020

Role of myosin in neurotransmitter release: functional studies at synapses formed in culture

1 reference

12 December 2020

Inhibition of neurotransmission by peptides containing the synaptic protein interaction site of N-type Ca2+ channels

1 reference

12 December 2020

Synaptotagmin has an essential function in synaptic vesicle positioning for synchronous release in addition to its role as a calcium sensor

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.156893

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978127%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

20978127

1 reference