(Q30502330)

English

A novel microtubule-modulating noscapinoid triggers apoptosis by inducing spindle multipolarity via centrosome amplification and declustering

scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

A novel microtubule-modulating noscapinoid triggers apoptosis by inducing spindle multipolarity via centrosome amplification and declustering (English)

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

8

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

author name string

P Karna

1

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

P C G Rida

2

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

V Pannu

3

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

K K Gupta

4

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

W B Dalton

5

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

H Joshi

6

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

V W Yang

7

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

R Aneja

9

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

publication date

5 November 2010

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Cell Death & Differentiation

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

18

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

4

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

632-644

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

A novel microtubule-modulating agent induces mitochondrially driven caspase-dependent apoptosis via mitotic checkpoint activation in human prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

EM011 activates a survivin-dependent apoptotic program in human non-small cell lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Aurora A, centrosome structure, and the centrosome cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Non-toxic melanoma therapy by a novel tubulin-binding agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

9-bromonoscapine-induced mitotic arrest of cigarette smoke condensate-transformed breast epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Antiangiogenic vinflunine affects EB1 localization and microtubule targeting to adhesion sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Centrosome amplification can initiate tumorigenesis in flies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Multidrug resistance-associated protein-overexpressing teniposide-resistant human lymphomas undergo apoptosis by a tubulin-binding agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Centriole overduplication through the concurrent formation of multiple daughter centrioles at single maternal templates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Synthesis of microtubule-interfering halogenated noscapine analogs that perturb mitosis in cancer cells followed by cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Rational design of the microtubule-targeting anti-breast cancer drug EM015.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

CLIP-170 facilitates the formation of kinetochore-microtubule attachments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Drug-resistant T-lymphoid tumors undergo apoptosis selectively in response to an antimicrotubule agent, EM011.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

The Polo kinase Plk4 functions in centriole duplication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

On the road to cancer: aneuploidy and the mitotic checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Centrosome amplification induced by hydroxyurea leads to aneuploidy in pRB deficient human and mouse fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Spindle multipolarity is prevented by centrosomal clustering.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Centrosomes split in the presence of impaired DNA integrity during mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Centrosome aberrations: cause or consequence of cancer progression?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Centrosome composition and microtubule anchoring mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Managing the centrosome numbers game: from chaos to stability in cancer cell division

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Noscapine inhibits tumor growth with little toxicity to normal tissues or inhibition of immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Vinblastine suppresses dynamics of individual microtubules in living interphase cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Neurotoxicity secondary to antineoplastic drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Centriole distribution during tripolar mitosis in Chinese hamster ovary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Tumor heterogeneity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

14 July 2018

Brominated derivatives of noscapine are potent microtubule-interfering agents that perturb mitosis and inhibit cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.133

21 January 2018

Development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and T-cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.133

21 January 2018

Treatment of hormone-refractory breast cancer: apoptosis and regression of human tumors implanted in mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.133

21 January 2018

Low rates of aneuploidy promote tumorigenesis while high rates of aneuploidy cause cell death and tumor suppression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131906

26 November 2018

Centriolar changes induced by vinblastine sulphate in the seminiferous epithelium of the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of pericentriolar material in multipolar spindles induced by colcemid treatment in Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21052096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/CDD.2010.133

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

ResearchGate publication ID

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