(Q30537821)

English

Hepatic sinusoidal endothelium avidly binds platelets in an integrin-dependent manner, leading to platelet and endothelial activation and leukocyte recruitment.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23257923%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Hepatic sinusoidal endothelium avidly binds platelets in an integrin-dependent manner, leading to platelet and endothelial activation and leukocyte recruitment (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23257923%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

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21 February 2020

4

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21 February 2020

author name string

John Herbert

2

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21 February 2020

Roy Bicknell

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21 February 2020

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20 December 2012

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21 February 2020

American Journal of Physiology - Gastrointestinal and Liver Physiology

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Europe PubMed Central

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21 February 2020

304

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23257923%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

5

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23257923%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

G469-78

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23257923%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3602682/fullTextXML

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The use of spinning-disk confocal microscopy for the intravital analysis of platelet dynamics in response to systemic and local inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Role of fibrinogen and protease-activated receptors in acute xenobiotic-induced cholestatic liver injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Protective and damaging effects of platelets in acute cholestatic liver injury revealed by depletion and inhibition strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Endothelium-platelet interactions in inflammatory lung disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Platelets contribute to the reduction of liver fibrosis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Liver regeneration: a spotlight on the novel role of platelets and serotonin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Platelets in liver transplantation: friend or foe?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

A novel method of differential gene expression analysis using multiple cDNA libraries applied to the identification of tumour endothelial genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Trafficking of recirculating lymphocytes in the rat liver: rapid transmigration into the portal area and then to the hepatic lymph.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Platelets, neutrophils, and neutrophil extracellular traps (NETs) in sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Histological assessment of non-alcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Human hepatic sinusoidal endothelial cells can be distinguished by expression of phenotypic markers related to their specialised functions in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Platelet-derived serotonin mediates liver regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Lymphoid neogenesis in chronic inflammatory diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Increased deposition of von Willebrand factor in the rat heart after local ionizing irradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Capillarization of Hepatic Sinusoid by Liver Endothelial Cell-Reactive Autoantibodies in Patients with Cirrhosis and Chronic Hepatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Platelets in hemostasis and thrombosis: role of integrins and their ligands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Vascular adhesion protein-1 mediates adhesion and transmigration of lymphocytes on human hepatic endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Using the transcriptome to annotate the genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Three-dimensional observations of the human hepatic artery (Arterial system in the liver).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Who gets alcoholic liver disease: nature or nurture?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Lymphocyte homing to allografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Activated platelets adherent to an intact endothelial cell monolayer bind flowing neutrophils and enable them to transfer to the endothelial surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

SAGEmap: a public gene expression resource

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Old concepts and new developments in the study of platelet aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Pathophysiology of ischaemia-reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Platelets induce sinusoidal endothelial cell apoptosis upon reperfusion of the cold ischemic rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

A public database for gene expression in human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Expression of P-selectin on hepatic endothelia and platelets promoting neutrophil removal by liver macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Circulating activated platelets reconstitute lymphocyte homing and immunity in L-selectin-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphaIIbbeta3 and stimulated by platelet-activating factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Human endothelial cells in culture and in vivo express on their surface all four components of the glycoprotein Ib/IX/V complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Adhesion of activated platelets to venous endothelial cells is mediated via GPIIb/IIIa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Morphologic investigation of sinusoidal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Pathology of alcoholic liver disease. VA Cooperative Study Group 119.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

von Willebrand factor mediates platelet adhesion to virally infected endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

The cell adhesion molecules of hepatic sinusoidal endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Role of the donor liver in the origin of platelet disorders and hyperfibrinolysis in liver transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Serial analysis of gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Characterization of the unique mechanism mediating the shear-dependent binding of soluble von Willebrand factor to platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Lymphocyte homing into lymph nodes: in vitro demonstration of the selective affinity of recirculating lymphocytes for high-endothelial venules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602682

20 June 2018

Agonist-activated alphavbeta3 on platelets and lymphocytes binds to the matrix protein osteopontin.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00407.2012

21 January 2018

Adhesion of activated platelets to endothelial cells: evidence for a GPIIbIIIa-dependent bridging mechanism and novel roles for endothelial intercellular adhesion molecule 1 (ICAM-1), alphavbeta3 integrin, and GPIbalpha

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00407.2012

21 January 2018

Neutrophil margination and extravasation in sinusoids and venules of liver during endotoxin-induced injury.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00407.2012

21 January 2018

Effectiveness of antiplatelet drugs against experimental non-alcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00407.2012

21 January 2018

Large-scale isolation of sinusoidal endothelial cells from pig and human liver.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00407.2012

21 January 2018

Identifying homing interactions in T-cell traffic in human disease.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00407.2012

21 January 2018

The Rho-kinase inhibitor Y-27632 inhibits cholestasis-induced platelet interactions in the hepatic microcirculation

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00407.2012

21 January 2018

Platelet adhesion in the sinusoid caused hepatic injury by neutrophils after hepatic ischemia reperfusion

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00407.2012

21 January 2018

Non-alcoholic hepatic steatosis and its relation to increased plasma biomarkers of inflammation and endothelial dysfunction in non-diabetic men. Role of visceral adipose tissue

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00407.2012

21 January 2018

Adhesive protein expression on thrombin-stimulated platelets: time-dependent modulation of anti-fibrinogen, -fibronectin, and -von Willebrand factor antibody binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/23257923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of the outcome of transplantation in man by platelet adherence in donor liver allografts. Evidence of the importance of prepreservation injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/23257923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion of flowing leucocytes to immobilized platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/23257923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of E-selectin and E-selectin ligands in human liver inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23257923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine treatment of endothelial cells increases glycoprotein Ib alpha-dependent adhesion to von Willebrand factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23257923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitronectin receptor (alpha(v)beta3) mediates platelet adhesion to the luminal aspect of endothelial cells: implications for reperfusion in acute myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/23257923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-Selectin mediates reperfusion injury through neutrophil and platelet sequestration in the warm ischemic mouse liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/23257923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated levels of von Willebrand Factor in cirrhosis support platelet adhesion despite reduced functional capacity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23257923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of vascular adhesion protein-1 on liver endothelium results in an NF-kappaB-dependent increase in lymphocyte adhesion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23257923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibrinogen deposition at the postischemic vessel wall promotes platelet adhesion during ischemia-reperfusion in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23257923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c7E3 Fab inhibits low shear flow modulated platelet adhesion to endothelium and surface-absorbed fibrinogen by blocking platelet GP IIb/IIIa as well as endothelial vitronectin receptor--results from patients with acute myocardial infarction and heal

1 reference

https://pubmed.ncbi.nlm.nih.gov/23257923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergism between platelets and leukocytes in inducing endothelial cell apoptosis in the cold ischemic rat liver: a Kupffer cell-mediated injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/23257923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPGI.00407.2012

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23257923%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23257923%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23257923%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

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