(Q30573867)

12 October 2017

Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein (English)

1 reference

12 October 2017

6

0 references

author name string

Manuel Wolters

1

1 reference

12 October 2017

Erin C Boyle

2

1 reference

12 October 2017

Kerstin Lardong

3

1 reference

12 October 2017

Konrad Trülzsch

4

1 reference

12 October 2017

Anika Steffen

5

1 reference

12 October 2017

Klaus Ruckdeschel

7

1 reference

12 October 2017

Martin Aepfelbacher

8

1 reference

12 October 2017

language of work or name

English

0 references

publication date

26 June 2013

1 reference

Journal of Biological Chemistry

12 October 2017

11

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

12 October 2017

288

1 reference

12 October 2017

32

1 reference

12 October 2017

23543-23553

1 reference

describes a project that uses

12 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3949328/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Salmonella virulence effector SopE and Host GEF ARNO cooperate to recruit and activate WAVE to trigger bacterial invasion.

28 July 2018

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WAVE regulatory complex activation by cooperating GTPases Arf and Rac1

28 July 2018

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28 July 2018

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RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts

28 July 2018

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Yersinia enterocolitica outer protein T (YopT).

28 July 2018

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Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs

28 July 2018

1 reference

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YopK regulates the Yersinia pestis type III secretion system from within host cells

28 July 2018

1 reference

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Destabilization of YopE by the ubiquitin-proteasome pathway fine-tunes Yop delivery into host cells and facilitates systemic spread of Yersinia enterocolitica in host lymphoid tissue

28 July 2018

1 reference

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Yersinia virulence factor YopM induces sustained RSK activation by interfering with dephosphorylation

28 July 2018

1 reference

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Cdc42 and vesicle trafficking in polarized cells.

28 July 2018

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Delineation of regions of the Yersinia YopM protein required for interaction with the RSK1 and PRK2 host kinases and their requirement for interleukin-10 production and virulence

28 July 2018

1 reference

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A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system

28 July 2018

1 reference

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The C-terminal tail of Yersinia pseudotuberculosis YopM is critical for interacting with RSK1 and for virulence

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Sequestering of Rac by the Yersinia effector YopO blocks Fcgamma receptor-mediated phagocytosis

28 July 2018

1 reference

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Mammalian Rho GTPases: new insights into their functions from in vivo studies

28 July 2018

1 reference

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In vitro signaling by MAPK and NFkappaB pathways inhibited by Yersinia YopJ.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Real-time analysis of effector translocation by the type III secretion system of enteropathogenic Escherichia coli

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Yersinia controls type III effector delivery into host cells by modulating Rho activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Invasion and dissemination of Yersinia enterocolitica in the mouse infection model

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Regulation of Yersinia Yop-effector delivery by translocated YopE.

28 July 2018

1 reference

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Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Yersinia virulence depends on mimicry of host Rho-family nucleotide dissociation inhibitors.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Rac1 is crucial for hair follicle integrity but is not essential for maintenance of the epidermis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Comparison of YopE and YopT activities in counteracting host signalling responses to Yersinia pseudotuberculosis infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Ubiquitin-mediated proteasomal degradation of Rho proteins by the CNF1 toxin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Yersinia's stratagem: targeting innate and adaptive immune defense.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Yersinia pseudotuberculosis spatially controls activation and misregulation of host cell Rac1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Rho GTPases: biochemistry and biology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Functions of the Yersinia effector proteins in inhibiting host immune responses

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Contribution of the major secreted yops of Yersinia enterocolitica O:8 to pathogenicity in the mouse infection model

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Identification of the secretion and translocation domain of the enteropathogenic and enterohemorrhagic Escherichia coli effector Cif, using TEM-1 beta-lactamase as a new fluorescence-based reporter

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Targeting Rac1 by the Yersinia effector protein YopE inhibits caspase-1-mediated maturation and release of interleukin-1beta

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Lck Dephosphorylation at Tyr-394 and Inhibition of T Cell Antigen Receptor Signaling by Yersinia Phosphatase YopH

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Cytotoxic necrotizing factor 1 of Escherichia coli stimulates Rho/Rho-kinase-dependent myosin light-chain phosphorylation without inactivating myosin light-chain phosphatase in endothelial cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Characterization of YopT effects on Rho GTPases in Yersinia enterocolitica-infected cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

The yersinia virulence factor YopM forms a novel protein complex with two cellular kinases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

The Yersinia Ysc-Yop 'type III' weaponry

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Proteasomal degradation of cytotoxic necrotizing factor 1-activated rac.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Yersinia pseudotuberculosis produces a cytotoxic necrotizing factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: a leucine-rich repeat protein with the shortest repeating unit

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

YopE of Yersinia, a GAP for Rho GTPases, selectively modulates Rac-dependent actin structures in endothelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

YopB of Yersinia enterocolitica is essential for YopE translocation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

A distinctive role for the Yersinia protein kinase: actin binding, kinase activation, and cytoskeleton disruption.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Suppression of T and B lymphocyte activation by a Yersinia pseudotuberculosis virulence factor, yopH

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

The cytotoxin YopT of Yersinia enterocolitica induces modification and cellular redistribution of the small GTP-binding protein RhoA

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Identification of p130Cas as a substrate of Yersinia YopH (Yop51), a bacterial protein tyrosine phosphatase that translocates into mammalian cells and targets focal adhesions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

YopK of Yersinia pseudotuberculosis controls translocation of Yop effectors across the eukaryotic cell membrane

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

The Yersinia Yop virulon: a bacterial system for subverting eukaryotic cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

YopK, a novel virulence determinant of Yersinia pseudotuberculosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Modulation of virulence factor expression by pathogen target cell contact

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Construction of a mobilizable Yersinia enterocolitica virulence plasmid.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Presence of a virulence-associated plasmid in Yersinia pseudotuberculosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Yersinia protein kinase YopO is activated by a novel G-actin binding process

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.448662

Functional analysis of the YopE GTPase-activating protein (GAP) activity of Yersinia pseudotuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.448662

A bacterial type III secretion system inhibits actin polymerization to prevent pore formation in host cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.448662

Yersinia enterocolitica targets cells of the innate and adaptive immune system by injection of Yops in a mouse infection model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.448662

A new turn in Rho GTPase activation by Escherichia coli cytotoxic necrotizing factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.448662

Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.448662

The Yersinia pseudotuberculosis cytotoxic necrotizing factor (CNFY) selectively activates RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.448662

21 January 2018

2 references

https://api.crossref.org/works/10.1074%2FJBC.M112.448662

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Temperature-inducible outer membrane protein of Yersinia pseudotuberculosis and Yersinia enterocolitica is associated with the virulence plasmid.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3949328

Effector functions of pathogenic Yersinia species

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23803609

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.448662

1 reference

12 October 2017

1 reference

12 October 2017

PubMed publication ID

23803609

1 reference