(Q30579223)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

Neural peptidase endothelin-converting enzyme 1 regulates endothelin 1-induced pruritus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

6

1 reference

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17 March 2020

Martin Steinhoff

19

1 reference

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17 March 2020

author name string

Makiko Kido-Nakahara

1

1 reference

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17 March 2020

Jörg Buddenkotte

2

1 reference

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17 March 2020

Cordula Kempkes

3

1 reference

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17 March 2020

Akihiko Ikoma

4

1 reference

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17 March 2020

Ferda Cevikbas

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Frank Nunes

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Stephan Seeliger

8

1 reference

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17 March 2020

Burcu Hasdemir

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Christian Mess

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Timo Buhl

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Mathias Sulk

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Frank-Ulrich Müller

13

1 reference

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17 March 2020

Dieter Metze

14

1 reference

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17 March 2020

Nigel W Bunnett

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Aditi Bhargava

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Earl Carstens

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Masutaka Furue

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

language of work or name

English

0 references

publication date

8 May 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

17 March 2020

published in

1 reference

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17 March 2020

volume

124

1 reference

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17 March 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

page(s)

2683-2695

1 reference

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describes a project that uses

17 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4038561/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Neural processing of itch

14 July 2018

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Endothelin-converting enzyme-1 regulates trafficking and signalling of the neurokinin 1 receptor in endosomes of myenteric neurones

14 July 2018

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14 July 2018

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TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch

14 July 2018

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Molecular signaling of pruritus induced by endothelin-1 in mice

14 July 2018

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Pathophysiology and therapy of pruritus in allergic and atopic diseases

14 July 2018

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Endosomes: a legitimate platform for the signaling train

14 July 2018

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TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms

14 July 2018

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Endosomal endothelin-converting enzyme-1: a regulator of beta-arrestin-dependent ERK signaling.

14 July 2018

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Endothelin-converting enzyme 1 promotes re-sensitization of neurokinin 1 receptor-dependent neurogenic inflammation

14 July 2018

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Intracellular degradation of somatostatin-14 following somatostatin-receptor3-mediated endocytosis in rat insulinoma cells

14 July 2018

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Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice.

14 July 2018

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Endothelin-converting enzyme-1 degrades internalized somatostatin-14.

14 July 2018

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Endothelin-1-induced pain and hyperalgesia: a review of pathophysiology, clinical manifestations and future therapeutic options

14 July 2018

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Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and beta-arrestins

14 July 2018

1 reference

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Endothelin potentiates TRPV1 via ETA receptor-mediated activation of protein kinase C.

14 July 2018

1 reference

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Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges

14 July 2018

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Endothelin-converting enzyme 1 degrades neuropeptides in endosomes to control receptor recycling

14 July 2018

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Endothelin-1 activates ETA receptors to cause reflex scratching in BALB/c mice

14 July 2018

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14 July 2018

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Neurophysiological, neuroimmunological, and neuroendocrine basis of pruritus

14 July 2018

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14 July 2018

The neurobiology of itch

1 reference

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Frontiers in pruritus research: scratching the brain for more effective itch therapy

14 July 2018

1 reference

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Mast cells and endothelin-1: a life-saving biological liaison?

14 July 2018

1 reference

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Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response.

14 July 2018

1 reference

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Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Imaging of central itch modulation in the human brain using positron emission tomography

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons

14 July 2018

1 reference

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Classical and alternative pathways of mast cell activation.

14 July 2018

1 reference

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Endothelin system: the double-edged sword in health and disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

The neurogenic vasodilator response to endothelin-1: a study in human skin in vivo

14 July 2018

1 reference

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Spinothalamic lamina I neurons selectively sensitive to histamine: a central neural pathway for itch

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Behavioral signs of acute pain produced by application of endothelin-1 to rat sciatic nerve.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Endothelin-1 induces vasodilation in human skin by nociceptor fibres and release of nitric oxide

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Specific C-receptors for itch in human skin.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

ECE-1: a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Endothelin 1, an endothelium-derived peptide, is expressed in neurons of the human spinal cord and dorsal root ganglia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Endothelin in brain: receptors, mitogenesis, and biosynthesis in glial cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Endothelins belong to the assortment of mast cell-derived and mast cell-bound cytokines

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Evaluation and management of a patient with chronic pruritus

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Role of transient receptor potential ankyrin subfamily member 1 in pruritus induced by endothelin-1.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Endothelin evokes distinct calcium transients in neuronal and non-neuronal cells of rat olfactory mucosa primary cultures

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

TLR2 and TLR4 agonists induce production of the vasoactive peptide endothelin-1 by human dendritic cells.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Behavioral differentiation between itch and pain in mouse

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Reduced endothelin converting enzyme-1 and endothelin-3 mRNA in the developing bowel of male mice may increase expressivity and penetrance of Hirschsprung disease-like distal intestinal aganglionosis.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Phospholipase Cbeta 3 mediates the scratching response activated by the histamine H1 receptor on C-fiber nociceptive neurons

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Neurotological and neuroanatomical changes in the connexin-26-related HID/KID syndrome.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Function and survival of dendritic cells depend on endothelin-1 and endothelin receptor autocrine loops.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Central activation by histamine-induced itch: analogies to pain processing: a correlational analysis of O-15 H2O positron emission tomography studies

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Neutral endopeptidase terminates substance P-induced inflammation in allergic contact dermatitis

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Responses of rat spinal dorsal horn neurons to intracutaneous microinjection of histamine, capsaicin, and other irritants

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038561

Endothelin-1 induces itch and pain in the mouse cheek model

26 November 2018

1 reference

12 December 2020

Regulation and intracellular trafficking pathways of the endothelin receptors

1 reference

12 December 2020

Internalization of type-A endothelin receptor

1 reference

12 December 2020

Regional haemodynamic effects of endothelin-1 in rat and man: unexpected adverse reaction

1 reference

12 December 2020

Discharge patterns of human C-fibers induced by itching and burning stimuli

1 reference

12 December 2020

Endothelin-1 induces release of histamine and leukotriene C4 from mouse bone marrow-derived mast cells

1 reference

12 December 2020

Autoregulation of endothelin-1 secretion by cultured human keratinocytes via the endothelin B receptor

1 reference

12 December 2020

Endothelin-1, one of the most potent histamine releasers in mouse peritoneal mast cells

1 reference

12 December 2020

Endothelin-induced nociception in mice: mediation by ETA and ETB receptors

1 reference

12 December 2020

Characterization of endothelin-induced nociception in mice: evidence for a mechanistically distinct analgesic model

1 reference

12 December 2020

Endothelin-1 causes pruritus in mice

1 reference

12 December 2020

Bradykinin is a potent pruritogen in atopic dermatitis: A switch from pain to itch

1 reference

12 December 2020

TRPV1 mediates histamine-induced itching via the activation of phospholipase A2 and 12-lipoxygenase

1 reference

12 December 2020

Local injection of endothelin-1 produces pain-like behavior and excitation of nociceptors in rats

1 reference

12 December 2020

Endothelin-1 participation in overt and inflammatory pain

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI67323

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24812665%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference