(Q30593472)

English

Interactions with actin monomers, actin filaments, and Arp2/3 complex define the roles of WASP family proteins and cortactin in coordinately regulating branched actin networks

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scholarly article

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Europe PubMed Central

PMC publication ID

18 October 2017

Interactions with actin monomers, actin filaments, and Arp2/3 complex define the roles of WASP family proteins and cortactin in coordinately regulating branched actin networks (English)

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

1 reference

based on heuristic

inferred from title

author name string

Luke A Helgeson

1

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Julianna G Prendergast

2

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Andrew R Wagner

3

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Max Rodnick-Smith

4

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Brad J Nolen

5

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

language of work or name

0 references

publication date

26 August 2014

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

number of pages

14

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

289

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

42

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

28856-28869

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4200246/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Structural analysis of the transitional state of Arp2/3 complex activation by two actin-bound WCAs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Inhibitory signalling to the Arp2/3 complex steers cell migration

1 reference

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20 June 2018

Dip1 defines a class of Arp2/3 complex activators that function without preformed actin filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Mechanism of synergistic activation of Arp2/3 complex by cortactin and N-WASP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change

1 reference

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20 June 2018

Stabilization of actin bundles by a dynamin 1/cortactin ring complex is necessary for growth cone filopodia.

1 reference

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20 June 2018

Activation of nucleation promoting factors for directional actin filament elongation: allosteric regulation and multimerization on the membrane

1 reference

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20 June 2018

Insertions within the actin core of actin-related protein 3 (Arp3) modulate branching nucleation by Arp2/3 complex

1 reference

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20 June 2018

Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex

1 reference

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20 June 2018

Phase transitions in the assembly of multivalent signalling proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Three-dimensional reconstructions of Arp2/3 complex with bound nucleation promoting factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Structural organization of the actin cytoskeleton at sites of clathrin-mediated endocytosis

1 reference

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20 June 2018

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Arp2/3 complex is bound and activated by two WASP proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Structural and biochemical characterization of two binding sites for nucleation-promoting factor WASp-VCA on Arp2/3 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Actin filament bundling by fimbrin is important for endocytosis, cytokinesis, and polarization in fission yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Characterization of dip1p reveals a switch in Arp2/3-dependent actin assembly for fission yeast endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Mechanism of a concentration-dependent switch between activation and inhibition of Arp2/3 complex by coronin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

A high precision survey of the molecular dynamics of mammalian clathrin-mediated endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Nucleating actin for invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

WAVE forms hetero- and homo-oligomeric complexes at integrin junctions in Drosophila visualized by bimolecular fluorescence complementation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Computer control of microscopes using µManager

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Quantitative analysis of the mechanism of endocytic actin patch assembly and disassembly in fission yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Actin, a central player in cell shape and movement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Dynamin2 GTPase and cortactin remodel actin filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

N-WASP and cortactin are involved in invadopodium-dependent chemotaxis to EGF in breast tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

The actin-binding domain of cortactin is dynamic and unstructured and affects lateral and longitudinal contacts in F-actin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Hierarchical regulation of WASP/WAVE proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Capping protein increases the rate of actin-based motility by promoting filament nucleation by the Arp2/3 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

X-ray scattering study of activated Arp2/3 complex with bound actin-WCA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Cortactin adopts a globular conformation and bundles actin into sheets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Inhibition of Arp2/3-mediated actin polymerization by PICK1 regulates neuronal morphology and AMPA receptor endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Multiple regulatory inputs converge on cortactin to control invadopodia biogenesis and extracellular matrix degradation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Distinct roles for Arp2/3 regulators in actin assembly and endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Mechanism of actin network attachment to moving membranes: barbed end capture by N-WASP WH2 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

The WASP-WAVE protein network: connecting the membrane to the cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

The ARP2/3 complex: an actin nucleator comes of age

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Harnessing actin dynamics for clathrin-mediated endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Cortactin has an essential and specific role in osteoclast actin assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Interactions of WASp, myosin-I, and verprolin with Arp2/3 complex during actin patch assembly in fission yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Cortactin promotes cell motility by enhancing lamellipodial persistence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Real-time measurements of actin filament polymerization by total internal reflection fluorescence microscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Critical conformational changes in the Arp2/3 complex are induced by nucleotide and nucleation promoting factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Regulation of actin dynamics by WASP and WAVE family proteins.

1 reference

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20 June 2018

Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Molecular requirements for actin-based lamella formation in Drosophila S2 cells

1 reference

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20 June 2018

Sequential interaction of actin-related proteins 2 and 3 (Arp2/3) complex with neural Wiscott-Aldrich syndrome protein (N-WASP) and cortactin during branched actin filament network formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Cortactin is a component of clathrin-coated pits and participates in receptor-mediated endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Essential role of neural Wiskott-Aldrich syndrome protein in podosome formation and degradation of extracellular matrix in src-transformed fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Activation of Arp2/3 complex-mediated actin polymerization by cortactin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Association of cortactin with dynamic actin in lamellipodia and on endosomal vesicles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Two tandem verprolin homology domains are necessary for a strong activation of Arp2/3 complex-induced actin polymerization and induction of microspike formation by N-WASP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia

1 reference

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20 June 2018

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Down-regulation of the filamentous actin cross-linking activity of cortactin by Src-mediated tyrosine phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4200246

20 June 2018

Interactions of ADF/cofilin, Arp2/3 complex, capping protein and profilin in remodeling of branched actin filament networks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.587527

21 January 2018

Cortactin releases the brakes in actin- based motility by enhancing WASP-VCA detachment from Arp2/3 branches.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.587527

21 January 2018

Interaction of cortactin and N-WASp with Arp2/3 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.587527

21 January 2018

An exact mathematical expression for describing competitive binding of two different ligands to a protein molecule.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.587527

21 January 2018

The verprolin-like central (vc) region of Wiskott-Aldrich syndrome protein induces Arp2/3 complex-dependent actin nucleation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.587527

21 January 2018

A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.587527

21 January 2018

Arg/Abl2 modulates the affinity and stoichiometry of binding of cortactin to F-actin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.587527

21 January 2018

Filamentous actin binding ability of cortactin isoforms is responsible for their cell-cell junctional localization in epithelial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.587527

21 January 2018

Effect of capping protein, CapZ, on the length of actin filaments and mechanical properties of actin filament networks

1 reference

https://pubmed.ncbi.nlm.nih.gov/25160634

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An invasion-related complex of cortactin, paxillin and PKCmu associates with invadopodia at sites of extracellular matrix degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25160634

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M114.587527

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

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