(Q30597676)

25 June 2017

title

Advantages and application of label-free detection assays in drug screening (English)

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25 June 2017

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Brian T Cunningham

1

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25 June 2017

Lance G Laing

series ordinal

2

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25 June 2017

language of work or name

English

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publication date

1 August 2008

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Expert Opinion on Drug Discovery

25 June 2017

published in

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25 June 2017

volume

3

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25 June 2017

issue

8

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25 June 2017

page(s)

891-901

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Optical probes and transducers

25 June 2017

cites work

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https://api.crossref.org/works/10.1517%2F17460441.3.8.891

Evaluation of cellular dielectric spectroscopy, a whole-cell, label-free technology for drug discovery on Gi-coupled GPCRs.

21 January 2018

1 reference

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Label-free assays on the BIND system.

21 January 2018

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A label-free optical technique for detecting small molecule interactions

21 January 2018

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Refractive index of proteins in organic solvents

21 January 2018

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Review: nuclear events in apoptosis

21 January 2018

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High throughput screening for protein kinase inhibitors

21 January 2018

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Small-molecule inhibition of TNF-alpha

21 January 2018

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Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry

21 January 2018

1 reference

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Small-Molecule Inhibitors of HIV-1 Protease Dimerization Derived from Cross-Linked Interfacial Peptides This work was supported by NIH (GM52739) and NSF (9457372-CHE).

21 January 2018

1 reference

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 January 2018

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Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer

21 January 2018

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

1 reference

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Solution‐Phase Combinatorial Libraries: Modulating Cellular Signaling by Targeting Protein–Protein or Protein–DNA Interactions

21 January 2018

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

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A label-free photonic crystal biosensor imaging method for detection of cancer cell cytotoxicity and proliferation

21 January 2018

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A flow cytometric method using Hoechst 33342 and propidium iodide for simultaneous cell cycle analysis and apoptosis determination in unfixed cells

21 January 2018

1 reference

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Bacteria detection using disposable optical leaky waveguide sensors

21 January 2018

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A randomised phase II study of two different schedules of pegylated liposomal doxorubicin in metastatic breast cancer (EORTC-10993).

21 January 2018

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Doxorubicin induces cell senescence preferentially over apoptosis in the FU-SY-1 synovial sarcoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.891

Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H(2)O(2)- and p53-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.891

Morphological changes in human spermatozoa as examined under scanning electron microscope after in vitro exposure to saponins isolated from Sapindus mukorossi

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.891

Effects of Bcl-2 modulation with G3139 antisense oligonucleotide on human breast cancer cells are independent of inherent Bcl-2 protein expression.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1517/17460441.3.8.891

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25 June 2017

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