(Q30631650)

25 June 2017

title

Replication protein A (RPA) binding to duplex cisplatin-damaged DNA is mediated through the generation of single-stranded DNA. (English)

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25 June 2017

Patrick SM

1

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25 June 2017

Turchi JJ

series ordinal

2

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25 June 2017

language of work or name

English

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publication date

1 May 1999

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Journal of Biological Chemistry

25 June 2017

published in

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25 June 2017

volume

274

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25 June 2017

issue

21

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25 June 2017

page(s)

14972-14978

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Cisplatin and DNA repair in cancer chemotherapy

25 June 2017

cites work

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The major adduct of the antitumor drug cis-diamminedichloroplatinum(II) with DNA bends the duplex by approximately equal to 40 degrees toward the major groove

21 January 2018

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DNA unwinding produced by site-specific intrastrand cross-links of the antitumor drug cis-diamminedichloroplatinum(II).

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Specific binding of chromosomal protein HMG1 to DNA damaged by the anticancer drug cisplatin

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Differential human nucleotide excision repair of paired and mispaired cisplatin-DNA adducts

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Complementation of the xeroderma pigmentosum DNA repair defect in cell-free extracts.

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Mammalian DNA nucleotide excision repair reconstituted with purified protein components.

21 January 2018

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Reconstitution of human DNA repair excision nuclease in a highly defined system

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DNA repair protein XPA binds replication protein A (RPA).

21 January 2018

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An interaction between the DNA repair factor XPA and replication protein A appears essential for nucleotide excision repair

21 January 2018

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Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA.

21 January 2018

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An affinity of human replication protein A for ultraviolet-damaged DNA.

21 January 2018

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RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

21 January 2018

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Functional analysis of human replication protein A in nucleotide excision repair

21 January 2018

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Replication protein A confers structure-specific endonuclease activities to the XPF-ERCC1 and XPG subunits of human DNA repair excision nuclease

21 January 2018

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Reconstitution of human excision nuclease with recombinant XPF-ERCC1 complex

21 January 2018

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Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein

21 January 2018

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DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair

21 January 2018

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Human replication protein A preferentially binds cisplatin-damaged duplex DNA in vitro

21 January 2018

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Cisplatin-DNA binding specificity of calf high-mobility group 1 protein

21 January 2018

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High-mobility group 1 protein inhibits helicase catalyzed displacement of cisplatin-damaged DNA.

21 January 2018

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High-mobility-group 1 protein mediates DNA bending as determined by ring closures

21 January 2018

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DNA unwinding activity of replication protein A

21 January 2018

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Replication protein A induces the unwinding of long double-stranded DNA regions

21 January 2018

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Denaturation of the simian virus 40 origin of replication mediated by human replication protein A.

21 January 2018

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Winding of the DNA helix by divalent metal ions

21 January 2018

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Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin

21 January 2018

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Distortions induced in double-stranded oligonucleotides by the binding of cis- or trans-diammine-dichloroplatinum(II) to the d(GTG) sequence

21 January 2018

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The solution structure of a DNA duplex containing the cis-Pt(NH3)2[d(-GTG-)-N7(G),N7(G)] adduct, as determined with high-field NMR and molecular mechanics/dynamics

21 January 2018

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Recognition of DNA adducts by human nucleotide excision repair. Evidence for a thermodynamic probing mechanism

21 January 2018

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Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism

21 January 2018

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Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA

21 January 2018

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Mechanisms of resistance to cisplatin

21 January 2018

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Recognition of DNA interstrand cross-links of cis-diamminedichloroplatinum(II) and its trans isomer by DNA-binding proteins

21 January 2018

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Mechanism of DNA-dependent protein kinase inhibition by cis-diamminedichloroplatinum(II)-damaged DNA

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.21.14972

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25 June 2017

1 reference