(Q30638019)

15 August 2017

Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kappaB activation in mouse colonocytes (English)

1 reference

15 August 2017

G C Kaiser

1

1 reference

15 August 2017

F Yan

series ordinal

2

1 reference

15 August 2017

D B Polk

series ordinal

3

1 reference

15 August 2017

language of work or name

English

0 references

publication date

1 March 1999

1 reference

15 August 2017

1 reference

15 August 2017

116

1 reference

15 August 2017

3

1 reference

15 August 2017

602-609

1 reference

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Limb and skin abnormalities in mice lacking IKKalpha

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Mitogen-activated protein kinase kinase 2 activation is essential for progression through the G2/M checkpoint arrest in cells exposed to ionizing radiation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Role of NF-kappaB in immune and inflammatory responses in the gut.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Activation of nuclear factor kappa B inflammatory bowel disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Tumor necrosis factor alpha regulates proliferation in a mouse intestinal cell line

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Current concepts of the etiology and pathogenesis of ulcerative colitis and Crohn's disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Cellular localization of tumor necrosis factor (TNF)-alpha transcripts in normal bowel and in necrotizing enterocolitis. TNF gene expression by Paneth cells, intestinal eosinophils, and macrophages.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Inhibition of NF-kappa B by sodium salicylate and aspirin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

zeta PKC induces phosphorylation and inactivation of I kappa B-alpha in vitro.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

NF-kappa B: a lesson in family values

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Sulfasalazine in the rheumatic disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Sulfasalazine inhibits the binding of TNF alpha to its receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

An experiment to determine the active therapeutic moiety of sulphasalazine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Recombinant IkappaB kinases alpha and beta are direct kinases of Ikappa Balpha

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Tumor necrosis factor alpha gene expression and the response to interferon in chronic hepatitis C.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Nonsteroidal antiinflammatory agents inhibit stimulated neutrophil adhesion to endothelium: adenosine dependent and independent mechanisms

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Intraluminal colonic release of immunoreactive tumour necrosis factor in chronic ulcerative colitis

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Tumor necrosis factor receptor-mediated signaling pathways

25 November 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Tumour-necrosis-factor antibody treatment in Crohn's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Tumor necrosis factor microsatellites define a Crohn's disease-associated haplotype on chromosome 6.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Sustained activation of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is required for megakaryocytic differentiation of K562 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Catalysis by a multiprotein IkappaB kinase complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Cytokine gene transcription of human colonic intraepithelial lymphocytes costimulated with epithelial cells bearing HLA-DR and its inhibition by 5-aminosalicylic acid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Inhibition of tumor necrosis factor-induced p42/p44 mitogen-activated protein kinase activation by sodium salicylate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Cell density-dependent regulation of PLC gamma 1 tyrosine phosphorylation and catalytic activity in an intestinal cell line (IEC-6).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Nuclear Translocation of fibroblast growth factor (FGF) receptors in response to FGF-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Sphingolipid metabolites differentially regulate extracellular signal-regulated kinase and stress-activated protein kinase cascades

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Sphingomyelin-derived lipids differentially regulate the extracellular signal-regulated kinase 2 (ERK-2) and c-Jun N-terminal kinase (JNK) signal cascades in airway smooth muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Sulfasalazine. Multiplicity of action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Homeostatic regulation of intestinal epithelia by intraepithelial gamma delta T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Systemic effects of cytokines released by gene-transduced tumor cells: marked hyperplasia induced in small bowel by gamma-interferon transfectants through host lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Dependence of epithelial growth of the small intestine on T-cell activation during weaning in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Mice lacking transforming growth factor alpha have an increased susceptibility to dextran sulfate-induced colitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Protective effect of epidermal growth factor in an experimental model of colitis in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Controlled trial of 4-ASA in ulcerative colitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Ceramide: a signal for apoptosis or mitogenesis?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Kinase suppressor of Ras is ceramide-activated protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

The NF-kappa B and I kappa B proteins: new discoveries and insights

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Effects of steroid treatment on activation of nuclear factor kappaB in patients with inflammatory bowel disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970182-4

Distribution studies of salicylazosulfapyridine and its metabolites

7 January 2021

1 reference

12 December 2020

Possible mode of action of 5-aminosalicylic acid

1 reference

12 December 2020

Elevated tumour necrosis factor-alpha (TNF-alpha) biological activity in psoriatic skin lesions

1 reference

12 December 2020

Protein kinase C-dependent activation of NF-kappaB in enterocytes is independent of IkappaB degradation

1 reference

12 December 2020

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

1 reference

12 December 2020

10.1016/S0016-5085(99)70182-4

Identifiers

DOI

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

10029619

1 reference