(Q30657899)

26 June 2017

title

Synthesis and characterization of HPMA copolymer-aminopropylgeldanamycin conjugates (English)

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26 June 2017

Y Kasuya

1

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26 June 2017

Z R Lu

2

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26 June 2017

P Kopecková

3

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26 June 2017

T Minko

4

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26 June 2017

S E Tabibi

5

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26 June 2017

J Kopecek

6

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26 June 2017

language of work or name

English

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publication date

1 July 2001

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Journal of Controlled Release

26 June 2017

published in

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26 June 2017

volume

74

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26 June 2017

issue

1-3

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26 June 2017

page(s)

203-211

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Geldanamycin. I. Structure assignment

26 June 2017

cites work

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7 January 2021

Geldanamycin, a new antibiotic

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Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

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7 January 2021

Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association

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7 January 2021

Inhibition of the oncogene product p185erbB-2 in vitro and in vivo by geldanamycin and dihydrogeldanamycin derivatives

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7 January 2021

erbB-2 oncogene inhibition by geldanamycin derivatives: synthesis, mechanism of action, and structure-activity relationships

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7 January 2021

The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin

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7 January 2021

DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90

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7 January 2021

The Hsp90 complex--a super-chaperone machine as a novel drug target

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7 January 2021

HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action

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7 January 2021

Early phase tumor accumulation of macromolecules: a great difference in clearance rate between tumor and normal tissues.

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7 January 2021

Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues

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7 January 2021

Antibody-directed affinity therapy applied to the immune system: in vivo effectiveness and limited toxicity of daunomycin conjugated to HPMA copolymers and targeting antibody

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7 January 2021

HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. 1. influence of the method of synthesis on the binding affinity to OVCAR-3 ovarian carcinoma cells in vitro

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7 January 2021

HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. II. Processing in epithelial ovarian carcinoma cells in vitro

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7 January 2021

Polymerizable Fab' antibody fragments for targeting of anticancer drugs

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7 January 2021

Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl) methacrylamide copolymers

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7 January 2021

Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate.

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7 January 2021

HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell line

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7 January 2021

Efficacy of the chemotherapeutic action of HPMA copolymer-bound doxorubicin in a solid tumor model of ovarian carcinoma.

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7 January 2021

Comparison of the anticancer effect of free and HPMA copolymer-bound adriamycin in human ovarian carcinoma cells.

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7 January 2021

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

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7 January 2021

Synthesis and evaluation of antiproliferative activity of a geldanamycin-Herceptin immunoconjugate

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7 January 2021

Effect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats.

1 reference

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7 January 2021

New types of synthetic infusion solutions. III. Elimination and retention of poly-[N-(2-hydroxypropyl)methacrylamide] in a test organism

1 reference

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7 January 2021

10.1016/S0168-3659(01)00318-2

Identifiers

DOI

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26 June 2017

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