(Q30665744)

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Prediction of isoprene diepoxide levels in vivo in mouse, rat and man using enzyme kinetic data in vitro and physiologically-based pharmacokinetic modelling

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 June 2017

Prediction of isoprene diepoxide levels in vivo in mouse, rat and man using enzyme kinetic data in vitro and physiologically-based pharmacokinetic modelling (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Bogaards JJ

1

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Freidig AP

2

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

van Bladeren PJ

3

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

publication date

1 December 2001

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Europe PubMed Central

PubMed publication ID

26 June 2017

Chemico-biological Interactions

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Europe PubMed Central

PubMed publication ID

26 June 2017

138

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Europe PubMed Central

PubMed publication ID

26 June 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

247-265

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Isoprene metabolism by liver microsomal mono-oxygenases.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

Hepatic microsomal metabolism of isoprene in various rodents

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

Stereoselectivity of in vitro isoprene metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

The biotransformation of isoprene and the two isoprene monoepoxides by human cytochrome P450 enzymes, compared to mouse and rat liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

Metabolism and molecular toxicology of isoprene

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

Metabolism and mutagenicity of isoprene

1 reference

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7 January 2021

Conjugation of isoprene monoepoxides with glutathione, catalyzed by alpha, mu, pi and theta-class glutathione S-transferases of rat and man

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

Physiologically based pharmacokinetic modeling of 1,3-butadiene, 1,2- epoxy-3-butene, and 1,2:3,4-diepoxybutane toxicokinetics in mice and rats

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats and mice

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

The role of hydrolysis in the detoxification of 1,2:3,4-diepoxybutane by human, rat, and mouse liver and lung in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

In vivo metabolism of butadiene by mice and rats: a comparison of physiological model predictions and experimental data

1 reference

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7 January 2021

Glutathione conjugation of 1,2:3,4- diepoxybutane in human liver and rat and mouse liver and lung in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans.

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

Physiologically based pharmacokinetics and the risk assessment process for methylene chloride.

1 reference

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7 January 2021

Physiological parameters in laboratory animals and humans

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

Prediction of interindividual variation in drug plasma levels in vivo from individual enzyme kinetic data and physiologically based pharmacokinetic modeling

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

Human hepatic microsomal epoxide hydrolase: comparative analysis of polymorphic expression

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

Isoenzyme(s) of glutathione transferase (class Mu) as a marker for the susceptibility to lung cancer: a follow up study

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

The human glutathione S-transferase supergene family, its polymorphism, and its effects on susceptibility to lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

Disposition of inhaled isoprene in B6C3F1 mice

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900276-9

7 January 2021

PBPK model for butadiene metabolism to epoxides: quantitative species differences in metabolism

1 reference

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7 January 2021

Identifiers

10.1016/S0009-2797(01)00276-9

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

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