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The biological functions of the methyl-CpG-binding protein MeCP2 and its implication in Rett syndrome.
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Europe PubMed Central
PubMed ID
11738839
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11738839%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
review article
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Europe PubMed Central
title
The biological functions of the methyl-CpG-binding protein MeCP2 and its implication in Rett syndrome
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11738839
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11738839%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
main subject
Rett syndrome
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author
Xinsheng Nan
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11738839
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11738839%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
Adrian Peter Bird
series ordinal
2
1 reference
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Europe PubMed Central
PubMed ID
11738839
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11738839%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
author name string
Nan X
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1
1 reference
stated in
Europe PubMed Central
PubMed ID
11738839
retrieved
26 June 2017
Bird A
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2
1 reference
stated in
Europe PubMed Central
PubMed ID
11738839
retrieved
26 June 2017
publication date
1 December 2001
1 reference
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Europe PubMed Central
PubMed ID
11738839
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11738839%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
published in
Brain and Development
1 reference
stated in
Europe PubMed Central
PubMed ID
11738839
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11738839%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
volume
23 Suppl 1
1 reference
stated in
Europe PubMed Central
PubMed ID
11738839
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11738839%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
page(s)
S32-7
1 reference
stated in
Europe PubMed Central
PubMed ID
11738839
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11738839%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
cites work
A progressive syndrome of autism, dementia, ataxia, and loss of purposeful hand use in girls: Rett's syndrome: report of 35 cases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rett syndrome: confirmation of X-linked dominant inheritance, and localization of the gene to Xq28.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Linkage analysis in Rett syndrome families suggests that there may be a critical region at Xq28
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromosome mapping of Rett syndrome: a likely candidate region on the telomere of Xq
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rett syndrome: a surprising result of mutation in MECP2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
X Inactivation in the Mouse Embryo Deficient for Dnmt1: Distinct Effect of Hypomethylation on Imprinted and Random X Inactivation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation-induced repression--belts, braces, and chromatin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active repression of methylated genes by the chromosomal protein MBD1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation specifies chromosomal localization of MeCP2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The solution structure of the domain from MeCP2 that binds to methylated DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of a family of mammalian methyl-CpG binding proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methyl-CpG-binding protein MeCP2 represses Sp1-activated transcription of the human leukosialin gene when the promoter is methylated
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The methyl-CpG binding transcriptional repressor MeCP2 stably associates with nucleosomal DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CpG methylation, chromatin structure and gene silencing-a three-way connection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of chromatin containing extensively acetylated H3 and H4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Butyrate suppression of histone deacetylation leads to accumulation of multiacetylated forms of histones H3 and H4 and increased DNase I sensitivity of the associated DNA sequences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Histone deacetylase: a regulator of transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The many HATs of transcription coactivators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
What's up and down with histone deacetylation and transcription?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acetylation: a regulatory modification to rival phosphorylation?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MeCP2 driven transcriptional repression in vitro: selectivity for methylated DNA, action at a distance and contacts with the basal transcription machinery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Histone deacetylase-independent transcriptional repression by methyl-CpG-binding protein 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of transcriptional regulation by methyl-CpG binding protein MBD1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The minimal repression domain of MBD2b overlaps with the methyl-CpG-binding domain and binds directly to Sin3A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rett syndrome: analysis of MECP2 and clinical characterization of 31 patients.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of the MECP2 gene in Japanese patients with Rett syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long-read sequence analysis of the MECP2 gene in Rett syndrome patients: correlation of disease severity with mutation type and location.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MECP2 mutation in male patients with non-specific X-linked mental retardation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of Rett syndrome mutations of the methyl-CpG binding domain of the transcriptional repressor MeCP2 on selectivity for association with methylated DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA recognition by the methyl-CpG binding domain of MeCP2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Treatment of Wilson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of expression of the FMR-1 gene in fragile X syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Large-scale chromatin unfolding and remodeling induced by VP16 acidic activation domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Applications of peptide nucleic acids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Triplex-directed modification of genes and gene activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-like double helix formed by peptide nucleic acid
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extended DNA-recognition repertoire of peptide nucleic acid (PNA): PNA-dsDNA triplex formed with cytosine-rich homopyrimidine PNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PNA-dependent gene chemistry: stable coupling of peptides and oligonucleotides to plasmid DNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0387-7604%2801%2900333-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0387-7604(01)00333-3
1 reference
stated in
Europe PubMed Central
PubMed ID
11738839
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11738839%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
PubMed ID
11738839
1 reference
stated in
Europe PubMed Central
PubMed ID
11738839
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11738839%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
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