(Q30699677)

26 June 2017

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title

Custom DNA-binding proteins come of age: polydactyl zinc-finger proteins (English)

1 reference

26 June 2017

Segal DJ

1

1 reference

PubMed ID

11849947

26 June 2017

Barbas CF 3rd

series ordinal

2

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26 June 2017

1 December 2001

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Current Opinion in Biotechnology

26 June 2017

1 reference

26 June 2017

12

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26 June 2017

6

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26 June 2017

632-637

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1997 Albert Lasker Award for Basic Medical Research. Control of gene transcription: an outline.

26 June 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Krüppel-associated boxes are potent transcriptional repression domains

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

GAL4-VP16 is an unusually potent transcriptional activator

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Design of novel sequence-specific DNA-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Initial sequencing and analysis of the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Expressing the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

The Sequence of the Human Genome

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Engineering polydactyl zinc-finger transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

From catalytic asymmetric synthesis to the transcriptional regulation of genes: in vivo and in vitro evolution of proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Building zinc fingers by selection: toward a therapeutic application

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Toward a code for the interactions of zinc fingers with DNA: selection of randomized fingers displayed on phage

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Selection of DNA binding sites for zinc fingers using rationally randomized DNA reveals coded interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Positive and negative regulation of endogenous genes by designed transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Synergy between adjacent zinc fingers in sequence-specific DNA recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Beyond the "recognition code": structures of two Cys2His2 zinc finger/TATA box complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Analysis of zinc fingers optimized via phage display: evaluating the utility of a recognition code

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Selection of zinc fingers that bind single-stranded telomeric DNA in the G-quadruplex conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

The new biology. Genomics fosters a "systems approach" and collaborations between academic, government, and industry scientists

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Transcriptional repression by zinc finger peptides. Exploring the potential for applications in gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Zinc finger proteins as designer transcription factors.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Significant effect of linker sequence on DNA recognition by multi-zinc finger protein

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Finger-positional change in three zinc finger protein Sp1: influence of terminal finger in DNA recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Multiconnection of identical zinc finger: implication for DNA binding affinity and unit modulation of the three zinc finger domain

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

DNA-bending finger: artificial design of 6-zinc finger peptides with polyglycine linker and induction of DNA bending

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Design of polyzinc finger peptides with structured linkers

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Improved DNA binding specificity from polyzinc finger peptides by using strings of two-finger units

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Selected peptide extension contacts hydrophobic patch on neighboring zinc finger and mediates dimerization on DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Chemically regulated zinc finger transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

A versatile framework for the design of ligand-dependent, transgene-specific transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

Zif268 protein-DNA complex refined at 1.6 A: a model system for understanding zinc finger-DNA interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2801%2900272-5

7 January 2021

10.1016/S0958-1669(01)00272-5

Identifiers

DOI

1 reference

26 June 2017

1 reference

PubMed ID

11849947