(Q30725106)

26 June 2017

Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein (English)

1 reference

26 June 2017

1 reference

P L Opresko

1

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26 June 2017

J P Laine

2

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26 June 2017

R M Brosh

3

1 reference

26 June 2017

M M Seidman

4

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26 June 2017

V A Bohr

5

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26 June 2017

language of work or name

English

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publication date

25 September 2001

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Journal of Biological Chemistry

26 June 2017

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26 June 2017

276

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26 June 2017

44677-44687

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26 June 2017

48

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Genetic analysis of ageing: role of oxidative damage and environmental stresses.

26 June 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Positional cloning of the Werner's syndrome gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

The Werner syndrome protein is a DNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Enzymatic and DNA binding properties of purified WRN protein: high affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Molecular genetics of Bloom's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

The Werner syndrome protein: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Mutator phenotype of Werner syndrome is characterized by extensive deletions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Werner syndrome protein: biochemical properties and functional interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

DNA damage and repair in telomeres: relation to aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Functional and physical interaction between WRN helicase and human replication protein A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Characterization of the human and mouse WRN 3'-->5' exonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Ku, a DNA repair protein with multiple cellular functions?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Selective blockage of the 3'-->5' exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Mechanisms of helicase-catalyzed DNA unwinding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

DNA helicases: 'inching forward'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Binding and melting of D-loops by the Bloom syndrome helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Ku binds telomeric DNA in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Mammalian telomeres end in a large duplex loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Characterization of genetic interactions with RFA1: the role of RPA in DNA replication and telomere maintenance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Werner syndrome protein. II. Characterization of the integral 3' --> 5' DNA exonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Chromosome instability in lymphocytes from a patient with Werner's syndrome is not associated with DNA repair defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Unwinding of a DNA triple helix by the Werner and Bloom syndrome helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

21 January 2018

Identifiers

DOI

10.1074/JBC.M107548200

1 reference

26 June 2017

1 reference