(Q30734343)

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Negative allosteric modulation of AMPA-preferring receptors by the selective isomer GYKI 53784 (LY303070), a specific non-competitive AMPA antagonist.

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12353057%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

1 reference

Europe PubMed Central

Negative allosteric modulation of AMPA-preferring receptors by the selective isomer GYKI 53784 (LY303070), a specific non-competitive AMPA antagonist (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12353057%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

author name string

Jérôme Ruel

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12353057%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Matthieu J Guitton

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12353057%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Jean-Luc Puell

3

1 reference

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13 December 2019

publication date

1 January 2002

1 reference

Europe PubMed Central

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13 December 2019

CNS Neuroscience & Therapeutics

1 reference

Europe PubMed Central

PMC publication ID

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13 December 2019

8

1 reference

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13 December 2019

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12353057%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

235-254

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12353057%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

The glutamate receptor ion channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of kainate-induced responses by pentobarbitone and GYKI-53784 in rat abducens motoneurons in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitatory amino acids and synaptic transmission in embryonic rat brainstem motoneurons in organotypic culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective neuroprotection by novel 2,3-benzodiazepine non-competitive AMPA antagonist against non-NMDA receptor-mediated excitotoxicity in primary rat hippocampal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of excitotoxicity in neurodegenerative disease: implications for therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPA-preferring glutamate receptors in cochlear physiology of adult guinea-pig.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of AMPA-mediated current after traumatic injury in cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subunit- and site-specific pharmacology of the NMDA receptor channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carbamazepine inhibits L-type Ca2+ channels in cultured rat hippocampal neurons stimulated with glutamate receptor agonists.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuroprotective and hypothermic effect of GYKI-52466, a non-competitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-antagonist on histological and behavioural variables in the gerbil global ischemia model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intermediate zone cells express calcium-permeable AMPA receptors and establish close contact with growing axons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two populations of kainate receptors with separate signaling mechanisms in hippocampal interneurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The contributions of GluR2 to allosteric modulation of AMPA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic 2,3-benzodiazepines, their specific binding to the basal ganglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative allosteric modulators of AMPA-preferring receptors inhibit [(3)H]GABA release in rat striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential modulation of the GYKI 53784-induced inhibition of AMPA currents by various AMPA-positive modulators in cerebellar Purkinje cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of desensitization of AMPA receptors on the neuronal viability and on the [Ca2+]ichanges in cultured rat hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The selective AMPA receptor antagonist GYKI 53784 blocks action potential generation and excitotoxicity in the guinea pig cochlea

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPA receptor antagonists, GYKI 52466 and NBQX, do not block the induction of long-term potentiation at therapeutically relevant concentrations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromatographic separation of 2,3-benzodiazepines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of learning processes by ionotropic glutamate receptor ligands.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2,3-benzodiazepine AMPA antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postischemic blockade of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NMDA receptor, NMDA antagonists and epilepsy therapy. A status report

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and desensitization of glutamate-activated channels mediating fast excitatory synaptic currents in the visual cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aniracetam reduces glutamate receptor desensitization and slows the decay of fast excitatory synaptic currents in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine-depleted rats and MPTP-treated monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic analysis of interactions between kainate and AMPA: Evidence for activation of a single receptor in mouse hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of the time course of fast EPSCs and glutamate channel kinetics by aniracetam

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of excitatory synaptic transmission by drugs that reduce desensitization at AMPA/kainate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist-activated cobalt uptake identifies divalent cation-permeable kainate receptors on neurons and glial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

9. Excitotoxicity and epileptic brain damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GYKI 52466 antagonizes glutamate responses but not NMDA and kainate responses in rat abducens motoneurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The epileptiform activity induced by 4-aminopyridine in rat amygdala slices: antagonism by non-N-methyl-D-aspartate receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitatory amino acid receptors in epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitatory amino acid neurotoxicity and neurodegenerative disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-NMDA receptor-mediated neurotoxicity in cortical culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate neurotoxicity in cortical cell culture is calcium dependent

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate and the pathophysiology of hypoxic--ischemic brain damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophysiological studies with a 2,3-benzodiazepine muscle relaxant: GYKI 52466.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate neurotoxicity and diseases of the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interaction between barbiturate anaesthetics and excitatory amino acid responses on cat spinal neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions among GYKI-52466, cyclothiazide, and aniracetam at recombinant AMPA and kainate receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional kainate-selective glutamate receptors in cultured hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavalin A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and cellular mechanisms of general anaesthesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-N-methyl-D-aspartate receptor antagonism by 3-N-substituted 2,3-benzodiazepines: relationship to anticonvulsant activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclothiazide acts at a site on the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor complex that does not recognize competitive or noncompetitive AMPA receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclothiazide reverses AMPA receptor antagonism of the 2,3-benzodiazepine, GYKI 53655

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential modulation by cyclothiazide and concanavalin A of desensitization at native alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid- and kainate-preferring glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential antagonism of alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid-preferring and kainate-preferring receptors by 2,3-benzodiazepines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective antagonism of AMPA receptors unmasks kainate receptor-mediated responses in hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The main pharmacological characteristics of Grandaxin (tofizopam, EGYT-341)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of AMPA receptors in trigeminal post-synaptic potentials recorded in rat abducens motoneurons in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical experience with excitatory amino acid antagonist drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged presence of glutamate during excitatory synaptic transmission to cerebellar Purkinje cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of fast excitatory synaptic transmission by cyclothiazide and GYKI 52466 in the rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of kinetic properties of AMPA receptor channels by nuclear RNA editing

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPA receptor antagonists and local cerebral glucose utilization in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synaptic model of memory: long-term potentiation in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A benzodiazepine recognition site associated with the non-NMDA glutamate receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-activity relationships in a series of 2(1H)-quinolones bearing different acidic function in the 3-position: 6,7-dichloro-2(1H)-oxoquinoline-3-phosphonic acid, a new potent and selective AMPA/kainate antagonist with neuroprotective properti

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of cyclothiazide on binding properties of AMPA-type glutamate receptors: lack of competition between cyclothiazide and GYKI 52466.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative allosteric modulation of wild-type and mutant AMPA receptors by GYKI 53655

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antagonist pharmacology of kainate- and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-preferring receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anesthetics produce subunit-selective actions on glutamate receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical synaptic transmission in the cochlea

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of 2,3-benzodiazepines and cyclothiazide at AMPA receptors: patch clamp recordings in cultured neurones and area CA1 in hippocampal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro: stereospecificity and selectivity profiles

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular targets for the rational design of antiepileptic drugs and related neuroprotective agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium in ischemic cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developing rat brainstem motoneurones in organotypic culture express calcium permeable AMPA-gated receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A tetrameric subunit stoichiometry for a glutamate receptor-channel complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tetrameric structure of a glutamate receptor channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPA receptor mediated excitotoxicity in neocortical neurons is developmentally regulated and dependent upon receptor desensitization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allosteric regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptors by thiocyanate and cyclothiazide at a common modulatory site distinct from that of 2,3-benzodiazepines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of GYKI 52466 and NBQX with cyclothiazide at AMPA receptors: experiments with outside-out patches and EPSCs in hippocampal neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/12353057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1527-3458.2002.TB00227.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12353057%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12353057%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12353057%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

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