(Q30773148)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10487529%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

title

Role of codon 160 in the sensitivity of human O6-alkylguanine-DNA alkyltransferase to O6-benzylguanine (English)

1 reference

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31 October 2019

2

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31 October 2019

author name string

M Xu-Welliver

1

1 reference

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31 October 2019

S Kanugula

3

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31 October 2019

W J Meehan

4

1 reference

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31 October 2019

A E Pegg

5

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31 October 2019

language of work or name

English

0 references

publication date

1 October 1999

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31 October 2019

published in

Biochemical Pharmacology

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31 October 2019

volume

58

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31 October 2019

issue

8

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31 October 2019

page(s)

1279-1285

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Mechanism of inactivation of human O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine

31 October 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

Modulation of O6-alkylguanine alkyltransferase-directed DNA repair in metastatic colon cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

O6-benzylguanine in humans: metabolic, pharmacokinetic, and pharmacodynamic findings

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

Simultaneous determination of O6-benzylguanine and 8-oxo-O6-benzylguanine in human plasma by reversed-phase high-performance liquid chromatography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

Phase I trial of O6-benzylguanine for patients undergoing surgery for malignant glioma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

Repair of O6-benzylguanine by the Escherichia coli Ada and Ogt and the human O6-alkylguanine-DNA alkyltransferases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

A polymorphism at codon 160 of human O6 methylguanine-DNA methyltransferase gene in young patients with adult type cancers and functional assay

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

The potential role of glycine-160 of human O6-alkylguanine-DNA alkyltransferase in reaction with O6-benzylguanine as determined by site-directed mutagenesis and molecular modelling comparisons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

Activation of human O6-alkylguanine-DNA alkyltransferase by DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

Investigation of the role of tyrosine-114 in the activity of human O6-alkylguanine-DNA alkyltranferase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

Effect of DNA on the inactivation of O6-alkylguanine-DNA alkyltransferase by 9-substituted O6-benzylguanine derivatives

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

Kinetic and DNA-binding properties of recombinant human O6-methylguanine-DNA methyltransferase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

Recombinant human O6-alkylguanine-DNA alkyltransferase induces conformational change in bound DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

Probing of conformational changes in human O6-alkylguanine-DNA alkyl transferase protein in its alkylated and DNA-bound states by limited proteolysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

Protection of CHO cells by mutant forms of O6-alkylguanine-DNA alkyltransferase from killing by 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) plus O6-benzylguanine or O6-benzyl-8-oxoguanine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900216-6

10.1016/S0006-2952(99)00216-6

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10487529%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference