(Q30784416)

26 June 2017

title

The R116C mutation in alpha A-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis (English)

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26 June 2017

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Usha P Andley

1

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26 June 2017

Harendra C Patel

series ordinal

2

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26 June 2017

Jing-Hua Xi

series ordinal

3

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26 June 2017

language of work or name

English

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publication date

27 December 2001

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Journal of Biological Chemistry

26 June 2017

published in

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26 June 2017

volume

277

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26 June 2017

issue

12

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26 June 2017

page(s)

10178-10186

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The function of alpha-crystallin in vision

26 June 2017

cites work

1 reference

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alpha B subunit of lens-specific protein alpha-crystallin is present in other ocular and non-ocular tissues

21 January 2018

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Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin

21 January 2018

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The molecular chaperone alphaA-crystallin enhances lens epithelial cell growth and resistance to UVA stress

21 January 2018

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Tumor necrosis factor-alpha induces changes in the phosphorylation, cellular localization, and oligomerization of human hsp27, a stress protein that confers cellular resistance to this cytokine.

21 January 2018

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Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1- and staurosporine-induced cell death.

21 January 2018

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Differential protective activity of alpha A- and alphaB-crystallin in lens epithelial cells.

21 January 2018

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The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Identification of 1,1'-bi(4-anilino)naphthalene-5,5'-disulfonic acid binding sequences in alpha-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Intermolecular exchange and stabilization of recombinant human alphaA- and alphaB-crystallin

21 January 2018

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Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA

21 January 2018

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A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy

21 January 2018

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Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

21 January 2018

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Lens differentiation. Crystallin synthesis in isolated epithelia from calf lenses

21 January 2018

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Linking genome and proteome by mass spectrometry: large-scale identification of yeast proteins from two dimensional gels

21 January 2018

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Routine identification of proteins from sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) gels or polyvinyl difluoride membranes using matrix assisted laser desorption/ionization-time of flight-mass spectrometry (MALDI-TOF-MS).

21 January 2018

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Comparative response to UV irradiation of cytoskeletal elements in rabbit and skate lens epithelial cells.

21 January 2018

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Ultrastructural localization of alpha A-crystallin to the bovine lens fiber cell cytoskeleton

21 January 2018

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Sense and antisense modification of glial alpha B-crystallin production results in alterations of stress fiber formation and thermoresistance

21 January 2018

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alphaB-crystallin interacts with cytoplasmic intermediate filament bundles during mitosis

21 January 2018

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Molecular chaperones: small heat shock proteins in the limelight

21 January 2018

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Small heat shock proteins, the cytoskeleton, and inclusion body formation

21 January 2018

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Small heat-shock proteins and their potential role in human disease

21 January 2018

1 reference

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Alpha B-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Signaling to chromatin through histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Megabase chromatin domains involved in DNA double-strand breaks in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Alpha-crystallin/small heat shock protein has autokinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

UV-induced changes in cell cycle and gene expression within rabbit lens epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Protein kinase A-catalyzed phosphorylation of heat shock protein 60 chaperone regulates its attachment to histone 2B in the T lymphocyte plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Functional characterization of human nucleosome assembly protein-2 (NAP1L4) suggests a role as a histone chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

In vivo observation of polypeptide flux through the bacterial chaperonin system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Identification of in vivo substrates of the chaperonin GroEL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Lens epithelial cells derived from alphaB-crystallin knockout mice demonstrate hyperproliferation and genomic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Cardiac alpha-crystallin. III. Involvement during heart ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Insight into the secondary structure of non-native proteins bound to a molecular chaperone alpha-crystallin. An isotope-edited infrared spectroscopic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

The mode of chaperoning of dithiothreitol-denatured alpha-lactalbumin by alpha-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Synthesis and characterization of a peptide identified as a functional element in alphaA-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Structural and functional consequences of the mutation of a conserved arginine residue in alphaA and alphaB crystallins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Mutation of R116C results in highly oligomerized alpha A-crystallin with modified structure and defective chaperone-like function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Binding of actin to lens alpha crystallins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Association of alpha-crystallin with actin in cultured lens cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

alpha-crystallin stabilizes actin filaments and prevents cytochalasin-induced depolymerization in a phosphorylation-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

Histone H2B phosphorylation in mammalian apoptotic cells. An association with DNA fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109211200

21 January 2018

Identifiers

DOI

10.1074/JBC.M109211200

1 reference

26 June 2017

1 reference