(Q30805567)

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Prediction of in vivo tissue distribution from in vitro data. 3. Correlation between in vitro and in vivo tissue distribution of a homologous series of nine 5-n-alkyl-5-ethyl barbituric acids

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Europe PubMed Central

PubMed publication ID

26 June 2017

Prediction of in vivo tissue distribution from in vitro data. 3. Correlation between in vitro and in vivo tissue distribution of a homologous series of nine 5-n-alkyl-5-ethyl barbituric acids (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

author name string

Peter Ballard

1

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

David E Leahy

2

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Malcolm Rowland

3

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

publication date

1 June 2003

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Europe PubMed Central

PubMed publication ID

26 June 2017

Pharmaceutical Research

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Europe PubMed Central

PubMed publication ID

26 June 2017

20

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Europe PubMed Central

PubMed publication ID

26 June 2017

6

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Europe PubMed Central

PubMed publication ID

26 June 2017

864-872

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Quantitative structure-pharmacokinetics relationships: I. Development of a whole-body physiologically based model to characterize changes in pharmacokinetics across a homologous series of barbiturates in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

12 December 2020

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Characterization of drug distribution and binding competition by two-chamber and multi-chamber distribution dialysis

1 reference

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Prediction of in vivo tissue distribution from in vitro data. 2. Influence of albumin diffusion from tissue pieces during an in vitro incubation on estimated tissue-to-unbound plasma partition coefficients (Kpu).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

12 December 2020

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Effects of biosolubility on pulmonary uptake and disposition of gases and vapors of lipophilic chemicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

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Prediction of drug distribution in vivo on the basis of in vitro binding data

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

12 December 2020

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Use of the tissue slice technique for evaluation of renal transport processes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

12 December 2020

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Prediction of pharmacokinetics prior to in vivo studies. II. Generic physiologically based pharmacokinetic models of drug disposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

12 December 2020

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Physiologic modeling of cyclosporin kinetics in rat and man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

12 December 2020

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Quantitative structure-pharmacokinetics relationships: II. A mechanistically based model to evaluate the relationship between tissue distribution parameters and compound lipophilicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

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Transport and binding of lidocaine by lung slices and perfused lung of rats.

1 reference

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Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution.

1 reference

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A physiologically based pharmacokinetic model for theophylline disposition in the pregnant and nonpregnant rat.

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Comparison between in-vivo and in-vitro tissue-to-plasma unbound concentration ratios (Kp,f) of quinidine in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

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Binding of organic compounds to rat liver and lung

1 reference

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Parabolic dependence of drug action upon lipophilic character as revealed by a study of hypnotics

1 reference

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Kinetics of distribution and adipose tissue storage as a function of lipophilicity and chemical structure. I. Barbiturates

1 reference

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Comparative physiologically based pharmacokinetics of hexobarbital, phenobarbital and thiopental in the rat.

1 reference

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Effect of a specific 5HT uptake inhibitor (citalopram) on drug accumulation by rat lung slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

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Estimation of tissue-to-plasma partition coefficients used in physiological pharmacokinetic models

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

12 December 2020

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Prediction of in vivo tissue distribution from in vitro data 1. Experiments with markers of aqueous spaces

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

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Preliminary Model for Methotrexate Pharmacokinetics

1 reference

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Relationship between lipophilicity and hepatic dispersion and distribution for a homologous series of barbiturates in the isolated perfused in situ rat liver.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

12 December 2020

based on heuristic

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Structure-pharmacokinetic relationships among the barbiturates in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

12 December 2020

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A physiologically based pharmacokinetic and pharmacodynamic model to describe the oral dosing of rats with ethyl acrylate and its implications for risk assessment

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

12 December 2020

based on heuristic

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In vitro and in vivo evaluation of the tissue-to-blood partition coefficient for physiological pharmacokinetic models

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ks values of some homologous series of barbiturates and the relationship with the lipophilicity and metabolic clearance

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of basic and acidic drugs to rat tissue subcellular fractions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

12 December 2020

based on heuristic

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Uptake of lipophilic model compounds into the isolated perfused rat epididymal adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/12817889

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based on heuristic

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Identifiers

10.1023/A:1023912318133

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

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