(Q30836220)

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Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

27 June 2017

Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 June 2017

author name string

Backes BJ

1

1 reference

Europe PubMed Central

PubMed publication ID

27 June 2017

Harris JL

2

1 reference

Europe PubMed Central

PubMed publication ID

27 June 2017

Leonetti F

3

1 reference

Europe PubMed Central

PubMed publication ID

27 June 2017

Craik CS

4

1 reference

Europe PubMed Central

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27 June 2017

Ellman JA

5

1 reference

Europe PubMed Central

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27 June 2017

publication date

1 February 2000

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Europe PubMed Central

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27 June 2017

Nature Biotechnology

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Europe PubMed Central

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27 June 2017

18

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Europe PubMed Central

PubMed publication ID

27 June 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

27 June 2017

187-193

1 reference

Europe PubMed Central

PubMed publication ID

27 June 2017

Substrate phage: selection of protease substrates by monovalent phage display

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Origins of the specificity of tissue-type plasminogen activator

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Determination of enzyme specificity in a complex mixture of peptide substrates by N-terminal sequence analysis

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Mapping the S' subsites of serine proteases using acyl transfer to mixtures of peptide nucleophiles

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Portion-mixing peptide libraries of quenched fluorogenic substrates for complete subsite mapping of endoprotease specificity

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Inhibition of cruzipain visualized in a fluorescence quenched solid-phase inhibitor library assay. D-amino acid inhibitors for cruzipain, cathepsin B and cathepsin L.

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Fluorescence-quenched solid phase combinatorial libraries in the characterization of cysteine protease substrate specificity

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On the size of the active site in proteases. I. Papain

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Peptide libraries: determination of relative reaction rates of protected amino acids in competitive couplings

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Crystal structure of the catalytic domain of human plasmin complexed with streptokinase

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Electronic distributions within protein phenylalanine aromatic rings are reflected by the three-dimensional oxygen atom environments

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Amino-aromatic interactions in proteins

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Structural determinants of specificity in the cysteine protease cruzain

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Molecular structural studies of human factor VIII

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Plasmin-mediated proteolysis of osteocalcin

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The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

1 reference

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Site-specific dissection of substrate recognition by thrombin

1 reference

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21 January 2018

Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes

1 reference

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21 January 2018

Domains specifying thrombin–receptor interaction

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Posttranslational sulfation of factor V is required for efficient thrombin cleavage and activation and for full procoagulant activity

1 reference

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Thrombin-catalyzed activation of recombinant human factor V.

1 reference

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A model for the specificity of fibrinogen cleavage by thrombin.

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Rapid chromatographic technique for preparative separations with moderate resolution

1 reference

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30 Human plasmin

1 reference

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Determination of the operational molarity of solutions of bovine α-chymotrypsin, trypsin, thrombin and factor Xa by spectrofluorimetric titration

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The Protein Data Bank: a computer-based archival file for macromolecular structures

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Plasmin Desensitization of the PAR1 Thrombin Receptor: Kinetics, Sites of Truncation, and Implications for Thrombolytic Therapy†

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Characterization of the substrate specificity of the major cysteine protease (cruzipain) from Trypanosoma cruzi using a portion-mixing combinatorial library and fluorogenic peptides.

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Plasmin converts factor X from coagulation zymogen to fibrinolysis cofactor

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Limited plasmin proteolysis of vitronectin. Characterization of the adhesion protein as morpho-regulatory and angiostatin-binding factor

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Plasmin cleavage of vitronectin Identification of the site and consequent attenuation in binding plasminogen activator inhibitor-1

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Study of the Specificity of Thrombin with Tripeptidyl-p-nitroanilide Substrates

1 reference

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7 January 2021

based on heuristic

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Characterization of the P2' and P3' specificities of thrombin using fluorescence-quenched substrates and mapping of the subsites by mutagenesis

1 reference

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The action of thrombin on peptide p-nitroanilide substrates. Substrate selectivity and examination of hydrolysis under different reaction conditions

1 reference

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Highly sensitive peptide-4-methylcoumaryl-7-amide substrates for blood-clotting proteases and trypsin

1 reference

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Recombinant human protein C derivatives: altered response to calcium resulting in enhanced activation by thrombin

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Sensitive assays for trypsin, elastase, and chymotrypsin using new fluorogenic substrates

1 reference

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Identifiers

1 reference

Europe PubMed Central

PubMed publication ID

27 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 June 2017

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