(Q30846616)

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A comprehensive alanine scanning mutagenesis of the Escherichia coli transcriptional activator SoxS: identifying amino acids important for DNA binding and transcription activation

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Europe PubMed Central

27 June 2017

A comprehensive alanine scanning mutagenesis of the Escherichia coli transcriptional activator SoxS: identifying amino acids important for DNA binding and transcription activation (English)

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Europe PubMed Central

27 June 2017

1 reference

based on heuristic

inferred from title

Escherichia coli

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based on heuristic

inferred from title

author name string

Kevin L Griffith

1

1 reference

Europe PubMed Central

27 June 2017

Richard E Wolf

2

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Europe PubMed Central

27 June 2017

language of work or name

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publication date

1 September 2002

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Europe PubMed Central

27 June 2017

Journal of Molecular Biology

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Europe PubMed Central

27 June 2017

322

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Europe PubMed Central

27 June 2017

2

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Europe PubMed Central

27 June 2017

237-257

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Europe PubMed Central

27 June 2017

Redox signaling and gene control in the Escherichia coli soxRS oxidative stress regulon--a review

1 reference

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Two-stage control of an oxidative stress regulon: the Escherichia coli SoxR protein triggers redox-inducible expression of the soxS regulatory gene

1 reference

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Two-stage induction of the soxRS (superoxide response) regulon of Escherichia coli

1 reference

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7 January 2021

Binuclear [2Fe-2S] clusters in the Escherichia coli SoxR protein and role of the metal centers in transcription

1 reference

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7 January 2021

The redox-regulated SoxR protein acts from a single DNA site as a repressor and an allosteric activator

1 reference

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7 January 2021

The redox state of the [2Fe-2S] clusters in SoxR protein regulates its activity as a transcription factor.

1 reference

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SoxR, a [2Fe-2S] transcription factor, is active only in its oxidized form

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Regulation of the soxRS oxidative stress regulon. Reversible oxidation of the Fe-S centers of SoxR in vivo

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Genome-wide transcriptional profiling of the Escherichia coli responses to superoxide stress and sodium salicylate

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Genomics of the marA/soxS/rob regulon of Escherichia coli: identification of directly activated promoters by application of molecular genetics and informatics to microarray data

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Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon.

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The mar regulon: multiple resistance to antibiotics and other toxic chemicals

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Repressor mutations in the marRAB operon that activate oxidative stress genes and multiple antibiotic resistance in Escherichia coli

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Activation of oxidative stress genes by mutations at the soxQ/cfxB/marA locus of Escherichia coli

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7 January 2021

Promoter discrimination by the related transcriptional activators MarA and SoxS: differential regulation by differential binding.

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7 January 2021

Differential expression of over 60 chromosomal genes in Escherichia coli by constitutive expression of MarA.

1 reference

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7 January 2021

marA, a regulated locus which controls expression of chromosomal multiple antibiotic resistance in Escherichia coli

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Overexpression of the MarA positive regulator is sufficient to confer multiple antibiotic resistance in Escherichia coli

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7 January 2021

Genetic and functional analysis of the multiple antibiotic resistance (mar) locus in Escherichia coli

1 reference

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Salicylate induction of antibiotic resistance in Escherichia coli: activation of the mar operon and a mar-independent pathway

1 reference

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7 January 2021

Binding of purified multiple antibiotic-resistance repressor protein (MarR) to mar operator sequences

1 reference

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7 January 2021

Activation of multiple antibiotic resistance and binding of stress-inducible promoters by Escherichia coli Rob protein

1 reference

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7 January 2021

An Escherichia coli curved DNA-binding protein whose expression is affected by the stationary phase-specific sigma factor sigma S.

1 reference

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Twelve species of the nucleoid-associated protein from Escherichia coli. Sequence recognition specificity and DNA binding affinity

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Two types of localization of the DNA-binding proteins within the Escherichia coli nucleoid

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Posttranscriptional activation of the transcriptional activator Rob by dipyridyl in Escherichia coli

1 reference

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7 January 2021

Crystal structure of the Escherichia coli Rob transcription factor in complex with DNA

1 reference

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7 January 2021

Molecular characterization of the soxRS genes of Escherichia coli: two genes control a superoxide stress regulon

1 reference

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7 January 2021

Two divergently transcribed genes, soxR and soxS, control a superoxide response regulon of Escherichia coli

1 reference

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Purification of a MalE-SoxS fusion protein and identification of the control sites of Escherichia coli superoxide-inducible genes

1 reference

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7 January 2021

Transcriptional activation of promoters of the superoxide and multiple antibiotic resistance regulons by Rob, a binding protein of the Escherichia coli origin of chromosomal replication

1 reference

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7 January 2021

Sequence specificity for DNA binding by Escherichia coli SoxS and Rob proteins

1 reference

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7 January 2021

Structural requirements for marbox function in transcriptional activation of mar/sox/rob regulon promoters in Escherichia coli: sequence, orientation and spatial relationship to the core promoter

1 reference

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7 January 2021

Interdependence of the position and orientation of SoxS binding sites in the transcriptional activation of the class I subset of Escherichia coli superoxide-inducible promoters

1 reference

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Systematic mutagenesis of the DNA binding sites for SoxS in the Escherichia coli zwf and fpr promoters: identifying nucleotides required for DNA binding and transcription activation

1 reference

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7 January 2021

Ambidextrous transcriptional activation by SoxS: requirement for the C-terminal domain of the RNA polymerase alpha subunit in a subset of Escherichia coli superoxide-inducible genes.

1 reference

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Autoactivation of the marRAB multiple antibiotic resistance operon by the MarA transcriptional activator in Escherichia coli

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Transcription activation by a variety of AraC/XylS family activators does not depend on the class II-specific activation determinant in the N-terminal domain of the RNA polymerase alpha subunit.

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Transcription activation at class II CAP-dependent promoters: two interactions between CAP and RNA polymerase

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A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator

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Probing the Escherichia coli transcriptional activator MarA using alanine-scanning mutagenesis: residues important for DNA binding and activation

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Measuring beta-galactosidase activity in bacteria: cell growth, permeabilization, and enzyme assays in 96-well arrays

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The role of internal packing interactions in determining the structure and stability of a protein

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Alternative packing arrangements in the hydrophobic core of λrepresser

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Complex formation between activator and RNA polymerase as the basis for transcriptional activation by MarA and SoxS in Escherichia coli.

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Evidence for "pre-recruitment" as a new mechanism of transcription activation in Escherichia coli: the large excess of SoxS binding sites per cell relative to the number of SoxS molecules per cell

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A global response induced in Escherichia coli by redox-cycling agents overlaps with that induced by peroxide stress.

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Positive control of a global antioxidant defense regulon activated by superoxide-generating agents in Escherichia coli

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Identification of amino acid-base pair contacts by genetic methods.

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Genetic evidence that transcription activation by RhaS involves specific amino acid contacts with sigma 70.

1 reference

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Hemiplegic mutations in AraC protein

1 reference

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Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter

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Overexpression of the robA gene increases organic solvent tolerance and multiple antibiotic and heavy metal ion resistance in Escherichia coli.

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based on heuristic

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Positive Control of Enzyme Synthesis by Gene C in the l -Arabinose System

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DNA bending by AraC: a negative mutant.

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based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0022-2836(02)00782-9

1 reference

Europe PubMed Central

27 June 2017

1 reference

Europe PubMed Central

27 June 2017

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