(Q30847239)

27 June 2017

1 reference

title

In silico predictions of drug solubility and permeability: two rate-limiting barriers to oral drug absorption (English)

1 reference

27 June 2017

1 reference

Christel A S Bergström

series ordinal

1

1 reference

27 June 2017

1 March 2005

1 reference

Basic and Clinical Pharmacology and Toxicology

27 June 2017

1 reference

27 June 2017

96

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27 June 2017

3

1 reference

27 June 2017

156-161

1 reference

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

27 June 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Prediction of aqueous solubility of a diverse set of compounds using quantitative structure-property relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 1. Prediction of intestinal absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Neural network modeling for estimation of the aqueous solubility of structurally related drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Molecular properties of WHO essential drugs and provisional biopharmaceutical classification

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Can the pharmaceutical industry reduce attrition rates?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Development of quantitative structure-property relationship models for early ADME evaluation in drug discovery. 2. Blood-brain barrier penetration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Evaluation of dynamic polar molecular surface area as predictor of drug absorption: comparison with other computational and experimental predictors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Polar molecular surface properties predict the intestinal absorption of drugs in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Prediction of intestinal absorption: comparative assessment of GASTROPLUS and IDEA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Enhancing the hit-to-lead properties of lead optimization libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Experimental and computational screening models for the prediction of intestinal drug absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

HT29-MTX/Caco-2 cocultures as an in vitro model for the intestinal epithelium: in vitro-in vivo correlation with permeability data from rats and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

ADMET in silico modelling: towards prediction paradise?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Molecular properties that influence the oral bioavailability of drug candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

A fuzzy ARTMAP based on quantitative structure-property relationships (QSPRs) for predicting aqueous solubility of organic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Experimental and computational screening models for prediction of aqueous drug solubility

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

Global and Local Computational Models for Aqueous Solubility Prediction of Drug-Like Molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-7843.2005.PTO960303.X

10.1111/J.1742-7843.2005.PTO960303.X

21 January 2018

Identifiers

DOI

1 reference

27 June 2017

1 reference

PubMed ID

15733209