(Q30868891)

27 June 2017

1 reference

title

Regulation and manipulation of the gene clusters encoding type-I PKSs (English)

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27 June 2017

Lal R

1

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27 June 2017

Kumari R

2

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27 June 2017

Kaur H

3

1 reference

27 June 2017

Khanna R

4

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27 June 2017

Dhingra N

5

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27 June 2017

Tuteja D

6

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27 June 2017

publication date

1 June 2000

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27 June 2017

published in

Trends in Biotechnology

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27 June 2017

volume

18

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27 June 2017

issue

6

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27 June 2017

page(s)

264-274

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Harnessing the biosynthetic code: combinations, permutations, and mutations

27 June 2017

cites work

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7 January 2021

Generation of polyketide libraries via combinatorial biosynthesis

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7 January 2021

Biosynthetic Studies of Daunorubicin and Tetracenomycin C

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7 January 2021

Harnessing the Biosynthetic Potential of Modular Polyketide Synthases

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7 January 2021

Combinatorial biosynthesis of erythromycin and complex polyketides

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7 January 2021

Engineering of modular polyketide synthases to produce novel polyketides

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7 January 2021

Nurturing nature: engineering new antibiotics

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7 January 2021

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

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7 January 2021

Modular organization of genes required for complex polyketide biosynthesis

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7 January 2021

Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products.

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7 January 2021

Origin of starter units for erythromycin biosynthesis.

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7 January 2021

Spontaneous priming of a downstream module in 6-deoxyerythronolide B synthase leads to polyketide biosynthesis

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7 January 2021

The loading domain of the erythromycin polyketide synthase is not essential for erythromycin biosynthesis in Saccharopolyspora erythraea

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7 January 2021

Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units

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7 January 2021

Mechanism and specificity of the terminal thioesterase domain from the erythromycin polyketide synthase

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7 January 2021

Organization of the enzymatic domains in the multifunctional polyketide synthase involved in erythromycin formation in Saccharopolyspora erythraea

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7 January 2021

Molecular basis of celmer's rules: the role of two ketoreductase domains in the control of chirality by the erythromycin modular polyketide synthase

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7 January 2021

Sonication-dependent electroporation of the erythromycin-producing bacterium Saccharopolyspora erythraea

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7 January 2021

An erythromycin analog produced by reprogramming of polyketide synthesis

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7 January 2021

Acyltransferase domain substitutions in erythromycin polyketide synthase yield novel erythromycin derivatives

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7 January 2021

Engineering broader specificity into an antibiotic-producing polyketide synthase.

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7 January 2021

Engineered biosynthesis of novel polyketides

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7 January 2021

Engineered biosynthesis of a complete macrolactone in a heterologous host

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7 January 2021

Evidence for two catalytically independent clusters of active sites in a functional modular polyketide synthase

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7 January 2021

A functional chimeric modular polyketide synthase generated via domain replacement

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7 January 2021

Construction of new vectors for high-level expression in actinomycetes.

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7 January 2021

The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin

1 reference

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7 January 2021

Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase

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7 January 2021

Rifamycins: strain improvement program

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7 January 2021

Engineering antibiotic producers to overcome the limitations of classical strain improvement programs

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7 January 2021

Development of an improved cloning vector and transformation system in Amycolatopsis mediterranei (Nocardia mediterranei)

1 reference

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7 January 2021

Selection of suitable marker genes for the development of cloning vectors and electroporation in different strains of Amycolatopsis mediterranei.

1 reference

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7 January 2021

The importance of homologous recombination in the generation of large deletions in hybrid plasmids in Amycolatopsis mediterranei

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7 January 2021

Recent trends in rifamycin research

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7 January 2021

Isolation and characterization of an extrachromosomal element from Nocardia mediterranei

1 reference

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7 January 2021

Efficient transformation of Amycolatopsis orientalis (Nocardia orientalis) protoplasts by Streptomyces plasmids

1 reference

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7 January 2021

A host-vector system for analysis and manipulation of rifamycin polyketide biosynthesis in Amycolatopsis mediterranei

1 reference

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7 January 2021

Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2800%2901443-8

7 January 2021

Cloning and sequence analysis of the putative rifamycin polyketide synthase gene cluster from Amycolatopsis mediterranei

1 reference

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7 January 2021

Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei

1 reference

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7 January 2021

Intermediates of rifamycin polyketide synthase produced by an Amycolatopsis mediterranei mutant with inactivated rifF gene

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7 January 2021

Biosynthesis of 3-Amino-5-hydroxybenzoic Acid, the Precursor of mC7N Units in Ansamycin Antibiotics†

1 reference

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7 January 2021

3-Amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.

1 reference

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7 January 2021

Crystal structure of 3-amino-5-hydroxybenzoic acid (AHBA) synthase

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7 January 2021

Direct evidence that the rifamycin polyketide synthase assembles polyketide chains processively.

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7 January 2021

Lessons from the rifamycin biosynthetic gene cluster

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7 January 2021

Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage

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7 January 2021

Manipulation of Modular Polyketide Synthases.

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7 January 2021

Biosynthesis of Erythromycin and Rapamycin.

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7 January 2021

Purification and characterization of bimodular and trimodular derivatives of the erythromycin polyketide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2800%2901443-8

7 January 2021

Molecular genetics of polyketides and its comparison to fatty acid biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2800%2901443-8

7 January 2021

Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2800%2901443-8

7 January 2021

A hybrid modular polyketide synthase obtained by domain swapping

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2800%2901443-8

7 January 2021

Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2800%2901443-8

7 January 2021

Functional orientation of the acyltransferase domain in a module of the erythromycin polyketide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2800%2901443-8

7 January 2021

A multiplasmid approach to preparing large libraries of polyketides

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2800%2901443-8

7 January 2021

Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analogues.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2800%2901443-8

7 January 2021

Dissecting and exploiting intermodular communication in polyketide synthases

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2800%2901443-8

7 January 2021

10.1016/S0167-7799(00)01443-8

Identifiers

DOI

1 reference

27 June 2017

1 reference