(Q30881821)

27 June 2017

1 reference

title

Use of transgenic animals for carcinogenicity testing: considerations and implications for risk assessment (English)

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27 June 2017

D Gulezian

1

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27 June 2017

D Jacobson-Kram

2

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27 June 2017

C B McCullough

3

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27 June 2017

H Olson

4

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27 June 2017

L Recio

5

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27 June 2017

D Robinson

6

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27 June 2017

R Storer

7

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27 June 2017

R Tennant

8

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27 June 2017

J M Ward

9

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27 June 2017

D A Neumann

10

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27 June 2017

language of work or name

English

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publication date

1 May 2000

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27 June 2017

published in

Toxicologic Pathology

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27 June 2017

volume

28

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27 June 2017

issue

3

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27 June 2017

page(s)

482-499

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Transgenic models of tumor development.

27 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Stable long-term germ-line transmission of transgene integration sites in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

A critical appraisal of the value of the mouse cancer bioassay in safety assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Complementation tagging of cooperating oncogenes in knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Myc-Max-Mad: a transcription factor network controlling cell cycle progression, differentiation and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Dermal carcinogenicity in transgenic mice: relative responsiveness of male and female hemizygous and homozygous Tg.AC mice to 12-O-tetradecanoylphorbol 13-acetate (TPA) and benzene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Rodent carcinogenicity bioassay: past, present, and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Knockouts. Targeting the mouse genome: a compendium of knockouts (Part I)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Targeting the mouse genome: a compendium of knockouts (part II)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Kinetics of wound-induced v-Ha-ras transgene expression and papilloma development in transgenic Tg.AC mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Induction of transgene expression in Tg.AC(v-Ha-ras) transgenic mice concomitant with DNA hypomethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Defective Repair Replication of DNA in Xeroderma Pigmentosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Xeroderma pigmentosum: a human disease in which an initial stage of DNA repair is defective

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

The rodent carcinogenicity bioassay produces a similar frequency of tumor increases and decreases: implications for risk assessment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant C3H mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Induction of DNA adducts and mutations in spleen, liver and lung of XPA-deficient/lacZ transgenic mice after oral treatment with benzo[a]pyrene: correlation with tumour development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

The p53-deficient mouse: a model for basic and applied cancer studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Genetic control of hepatocarcinogenesis in C57BL/6J and C3H/HeJ inbred mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Modeling tumor onset and multiplicity using transition models with latent variables.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Carcinogenic responses of transgenic heterozygous p53 knockout mice to inhaled 239PuO2 or metallic beryllium

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

The morphology, immunohistochemistry, and incidence of hematopoietic neoplasms in mice and rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Transgenic mice as probes into complex systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Data analysis: statistical analysis and use of historical control data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Point mutations of the c-H-ras gene in spontaneous liver tumors of transgenic mice carrying the human c-H-ras gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Characterization of p53 mutations in methylene chloride-induced lung tumors from B6C3F1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

p53 mutations in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

'Cold SSCP': a simple, rapid and non-radioactive method for optimized single-strand conformation polymorphism analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Calorie restriction delays spontaneous tumorigenesis in p53-knockout transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Tumor spectrum analysis in p53-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

p53 mutations are absent from carcinogen-induced mouse liver tumors but occur in cell lines established from these tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

The role of DNA methylation in cancer genetic and epigenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

DNA damage, oncogenesis and the p53 tumour-suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Stochastic modelling of tumorigenesis in p53 deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

The contribution of the mouse in hazard identification studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Carcinogenic properties of pharmaceutical agents evaluated in the IARC Monographs programme

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Transgenic animal models for measuring mutations in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Pathological features of spontaneous and induced tumors in transgenic mice carrying a human prototype c-Ha-ras gene used for six-month carcinogenicity studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Mutation and cancer: a model for human carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Two-event model for carcinogenesis: biological, mathematical, and statistical considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Cell proliferation and carcinogenesis models: general principles with illustrations from the rodent liver system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Two genes abrogate the inhibition of murine hepatocarcinogenesis by ovarian hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Xeroderma pigmentosum. An inherited diseases with sun sensitivity, multiple cutaneous neoplasms, and abnormal DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Analysis of the Ha-ras oncogene in C3H/He mouse liver tumours derived spontaneously or induced with diethylintrosamine or phenobarbitone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Phenobarbital does not promote hepatic tumorigenesis in a twenty-six-week bioassay in p53 heterozygous mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Chemically induced skin carcinogenesis in a transgenic mouse line (TG.AC) carrying a v-Ha-ras gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Bioassay design and MTD setting: old methods and new approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

FVB/N: an inbred mouse strain preferable for transgenic analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

An evaluation of the hemizygous transgenic Tg.AC mouse for carcinogenicity testing of pharmaceuticals. II. A genotypic marker that predicts tumorigenic responsiveness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Cloning and characterization of the mouse XPAC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Use of DNA repair-deficient XPA transgenic mice in short-term carcinogenicity testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Cancer susceptibility genes and molecular carcinogenesis. American Association for Cancer Research Special Conference: Cancer Susceptibility Genes and Molecular Carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Validation of transgenic mice carrying the human prototype c-Ha-ras gene as a bioassay model for rapid carcinogenicity testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Strain dependency of B and T lymphoma development in immunoglobulin heavy chain enhancer (E mu)-myc transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

Strain-dependent epithelial defects in mice lacking the EGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800320

10.1177/019262330002800320

21 January 2018

Identifiers

DOI

1 reference

27 June 2017

1 reference