(Q30883432)

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Stepwise manipulation of DNA specificity in Flp recombinase: progressively adapting Flp to individual and combinatorial mutations in its target site

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scholarly article

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Europe PubMed Central

27 June 2017

Stepwise manipulation of DNA specificity in Flp recombinase: progressively adapting Flp to individual and combinatorial mutations in its target site (English)

1 reference

Europe PubMed Central

27 June 2017

author name string

Yuri Voziyanov

1

1 reference

Europe PubMed Central

27 June 2017

Jay H Konieczka

2

1 reference

Europe PubMed Central

27 June 2017

A Francis Stewart

3

1 reference

Europe PubMed Central

27 June 2017

Makkuni Jayaram

4

1 reference

Europe PubMed Central

27 June 2017

language of work or name

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publication date

1 February 2003

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Europe PubMed Central

27 June 2017

Journal of Molecular Biology

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Europe PubMed Central

27 June 2017

326

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Europe PubMed Central

27 June 2017

65-76

1 reference

Europe PubMed Central

27 June 2017

1

1 reference

Europe PubMed Central

27 June 2017

Flexibility in DNA recombination: structure of the lambda integrase catalytic core

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Molecular organization in site-specific recombination: the catalytic domain of bacteriophage HP1 integrase at 2.7 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Crystal structure of the site-specific recombinase, XerD.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Crystal structure of a Flp recombinase-Holliday junction complex: assembly of an active oligomer by helix swapping

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

The integrase family of tyrosine recombinases: evolution of a conserved active site domain

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Similarities and differences among 105 members of the Int family of site-specific recombinases

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Site-specific recombinases: tools for genome engineering.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

From mouse to man: generating megabase chromosome rearrangements

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Alteration of Cre recombinase site specificity by substrate-linked protein evolution.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Directed evolution of the site specificity of Cre recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Non-contact positions impose site selectivity on Cre recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

A dual reporter screening system identifies the amino acid at position 82 in Flp site-specific recombinase as a determinant for target specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

DNA recognition by the FLP recombinase of the yeast 2 mu plasmid. A mutational analysis of the FLP binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Improved properties of FLP recombinase evolved by cycling mutagenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Chimeras of the Flp and Cre recombinases: tests of the mode of cleavage by Flp and Cre

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Identifying determinants of recombination specificity: construction and characterization of mutant bacteriophage integrases

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Role of arginine-43 and arginine-69 of the Hin recombinase catalytic domain in the binding of Hin to the hix DNA recombination sites.

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Structure and function of type II restriction endonucleases

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Site-directed mutagenesis studies with EcoRV restriction endonuclease to identify regions involved in recognition and catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

EcoRV restriction endonuclease: communication between DNA recognition and catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Mg2+ binding to the active site of EcoRV endonuclease: a crystallographic study of complexes with substrate and product DNA at 2 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Protein-DNA recognition complexes: conservation of structure and binding energy in the transition state

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Understanding the immutability of restriction enzymes: crystal structure of BglII and its DNA substrate at 1.5 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Functional roles of individual recombinase monomers in strand breakage and strand union during site-specific DNA recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Geometry of site alignment during int family recombination: antiparallel synapsis by the Flp recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

Protein modelling for all

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901364-5

7 January 2021

WHAT IF: a molecular modeling and drug design program

1 reference

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7 January 2021

Identifiers

10.1016/S0022-2836(02)01364-5

1 reference

Europe PubMed Central

27 June 2017

release_7vmu7uraszbqtevwlkktk6qt7y

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24 November 2022

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Europe PubMed Central

27 June 2017

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