(Q30885862)

27 June 2017

title

Identification of new Cdc25 dual specificity phosphatase inhibitors in a targeted small molecule array (English)

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27 June 2017

Ducruet AP

1

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27 June 2017

Rice RL

2

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27 June 2017

Tamura K

3

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27 June 2017

Yokokawa F

4

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27 June 2017

Yokokawa S

5

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27 June 2017

Wipf P

6

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27 June 2017

Lazo JS

7

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27 June 2017

language of work or name

English

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publication date

1 June 2000

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Bioorganic & Medicinal Chemistry

27 June 2017

published in

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27 June 2017

volume

8

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27 June 2017

issue

6

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27 June 2017

page(s)

1451-1466

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A targeted library of small-molecule, tyrosine, and dual-specificity phosphatase inhibitors derived from a rational core design and random side chain variation

27 June 2017

cites work

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Potent and highly selective inhibitors of the protein tyrosine phosphatase 1B

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Form and function in protein dephosphorylation

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Protein tyrosine phosphatase 1B interacts with the activated insulin receptor

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Direct binding of the proline-rich region of protein tyrosine phosphatase 1B to the Src homology 3 domain of p130(Cas)

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7 January 2021

Extracellular regulated kinases (ERK) 1 and ERK2 are authentic substrates for the dual-specificity protein-tyrosine phosphatase VHR. A novel role in down-regulating the ERK pathway

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Crystal structure of the dual specificity protein phosphatase VHR

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Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A

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Alternative splicing of the human CDC25B tyrosine phosphatase. Possible implications for growth control?

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Hyperphosphorylation of the N-terminal domain of Cdc25 regulates activity toward cyclin B1/Cdc2 but not cyclin A/Cdk2

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Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate

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7 January 2021

Combinatorial synthesis and biological evaluation of library of small-molecule Ser/Thr-protein phosphatase inhibitors

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7 January 2021

Generation of an Ugi library of phosphate mimic-containing compounds and identification of novel dual specific phosphatase inhibitors

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7 January 2021

Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design

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7 January 2021

Dual G1 and G2/M phase inhibition by SC-alpha alpha delta 9, a combinatorially derived Cdc25 phosphatase inhibitor

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7 January 2021

Dysidiolide: A Novel Protein Phosphatase Inhibitor from the Caribbean SpongeDysidea etheriade Laubenfels

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7 January 2021

Dysidiolide and related gamma-hydroxy butenolide compounds as inhibitors of the protein tyrosine phosphatase, CDC25

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7 January 2021

Novel CDC25A phosphatase inhibitors from pyrolysis of 3-alpha-azido-B-homo-6-oxa-4-cholesten-7-one on silica gel

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The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product

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7 January 2021

10.1016/S0968-0896(00)00069-9

Identifiers

DOI

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27 June 2017

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