(Q30890428)

27 June 2017

title

Internalizing antibodies and targeted cancer therapy: direct selection from phage display libraries (English)

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27 June 2017

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Nielsen UB

1

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27 June 2017

Marks JD

series ordinal

2

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27 June 2017

language of work or name

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1 August 2000

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Pharmaceutical science & technology today

27 June 2017

published in

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27 June 2017

volume

3

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27 June 2017

issue

8

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27 June 2017

page(s)

282-291

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Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains

27 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

By-passing immunization. Human antibodies from V-gene libraries displayed on phage

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Phage libraries--a new route to clinically useful antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Making antibodies by phage display technology

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Recombinant immunotoxin containing a disulfide-stabilized Fv directed at erbB2 that does not require proteolytic activation

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Prolonged in vivo tumour retention of a human diabody targeting the extracellular domain of human HER2/neu

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Multivalent Fvs: characterization of single-chain Fv oligomers and preparation of a bispecific Fv

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Charge-modified single chain antibody constructs of monoclonal antibody CC49: generation, characterization, pharmacokinetics, and biodistribution analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

First MAb approved for treatment of metastatic breast cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Growth inhibition of CD20-positive B lymphoma cell lines by IDEC-C2B8 anti-CD20 monoclonal antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Homodimerization of tumor-reactive monoclonal antibodies markedly increases their ability to induce growth arrest or apoptosis of tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Humanization of an anti-p185HER2 antibody for human cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Development of anti-p185HER2 immunoliposomes for cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

The performance of e23(Fv)PEs, recombinant toxins targeting the erbB-2 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

A subclass of tumor-inhibitory monoclonal antibodies to ErbB-2/HER2 blocks crosstalk with growth factor receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Two EGF molecules contribute additively to stabilization of the EGFR dimer

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Fc receptor isoforms exhibit distinct abilities for coated pit localization as a result of cytoplasmic domain heterogeneity.

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

1 reference

7 January 2021

pH and the recycling of transferrin during receptor-mediated endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Antitumour activity of an immunoconjugate composed of anti-human astrocytoma monoclonal antibody and neocarzinostatin

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Receptor-mediated and enzyme-dependent targeting of cytotoxic anticancer drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Target cell-specific DNA transfer mediated by a chimeric multidomain protein. Novel non-viral gene delivery system

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer.

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: results of a multicenter phase II trial

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Targeting of stealth liposomes to erbB-2 (Her/2) receptor: in vitro and in vivo studies

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

CD4 and CD7 molecules as targets for drug delivery from antibody bearing liposomes

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Cellular Trafficking and Cytotoxicity of Anti-Cd19-Targeted Liposomal Doxorubicin in B Lymphoma Cells

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Anti-HER2 immunoliposomes for targeted therapy of human tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Recombinant Fv immunotoxins and Fv fragments as novel agents for cancer therapy and diagnosis

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Cytotoxicity of gelonin and its conjugates with antibodies is determined by the extent of their endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Processing of antibody-radioisotope conjugates after binding to the surface of tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Immunoscintigraphy of small-cell lung cancer xenografts with anti neural cell adhesion molecule monoclonal antibody, 123C3: improvement of tumour uptake by internalisation

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Therapeutic efficacy and dose-limiting toxicity of Auger-electron vs. beta emitters in radioimmunotherapy with internalizing antibodies: evaluation of 125I- vs. 131I-labeled CO17-1A in a human colorectal cancer model

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Selection of monoclonal antibodies which induce internalization and phosphorylation of p185HER2 and growth inhibition of cells with HER2/NEU gene amplification.

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Modulation of transferrin receptor expression and function by anti-transferrin receptor antibodies and antibody fragments

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Comparison of the biological properties of two anti-mucin-1 antibodies prepared for imaging and therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Targeting behavior of rat monoclonal IgG antibodies in vivo: role of antibody isotype, specificity and the target cell antigen density

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Antigen density on target cells determines the immunosuppressive potential of rat IgG2b monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Antibody-targeted drugs for the therapy of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Evaluation of four CD22 antibodies as ricin A chain-containing immunotoxins for the in vivo therapy of human B-cell leukemias and lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Monoclonal antibodies against receptor for epidermal growth factor induce early and delayed effects of epidermal growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Monoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Agonistic antibodies stimulate the kinase encoded by the neu protooncogene in living cells but the oncogenic mutant is constitutively active

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Antibody-induced activation of p185HER2 in the human lung adenocarcinoma cell line Calu-3 requires bivalency

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Differential immunofluorescent staining of polymorphonuclear leucocytes for discriminating between surface bound and internalised immunoglobulin

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Cell membrane antigen-antibody complex dissociation by the widely used glycine-HCL method: an unreliable procedure for studying antibody internalization

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

A recombinant antibody with the antigen-specific, major histocompatibility complex-restricted specificity of T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Toward cell-targeting gene therapy vectors: selection of cell-binding peptides from random peptide-presenting phage libraries

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Anti-melanoma antibodies from melanoma patients immunized with genetically modified autologous tumor cells: selection of specific antibodies from single-chain Fv fusion phage libraries

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Selection-dominant and nonaccessible epitopes on cell-surface receptors revealed by cell-panning with a large phage antibody library

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Toward selection of internalizing antibodies from phage libraries

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

In vitro and in vivo characterization of a human anti-c-erbB-2 single-chain Fv isolated from a filamentous phage antibody library

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Selection of tumor-specific internalizing human antibodies from phage libraries

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1461-5347%2800%2900280-7

7 January 2021

10.1016/S1461-5347(00)00280-7

Identifiers

DOI

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27 June 2017

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