(Q30912463)

27 June 2017

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title

Anchoring notch genetics and biochemistry; structural analysis of the ankyrin domain sheds light on existing data (English)

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27 June 2017

Olga Y Lubman

1

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27 June 2017

Sergey V Korolev

series ordinal

2

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27 June 2017

Raphael Kopan

series ordinal

3

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27 June 2017

publication date

1 March 2004

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27 June 2017

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27 June 2017

volume

13

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27 June 2017

issue

5

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27 June 2017

page(s)

619-626

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Notch signaling: cell fate control and signal integration in development

27 June 2017

cites work

1 reference

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7 January 2021

The origin of the ankyrin repeat region in Notch intracellular domains is critical for regulation of HES promoter activity

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7 January 2021

Hundreds of ankyrin-like repeats in functionally diverse proteins: mobile modules that cross phyla horizontally?

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7 January 2021

Limits of cooperativity in a structurally modular protein: response of the Notch ankyrin domain to analogous alanine substitutions in each repeat

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7 January 2021

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

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7 January 2021

SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans

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7 January 2021

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

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7 January 2021

Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways

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7 January 2021

Glycogen synthase kinase-3beta modulates notch signaling and stability

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7 January 2021

Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling

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7 January 2021

Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex

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7 January 2021

Structure/function studies of lin-12/Notch proteins.

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Notch signaling and inherited disease syndromes

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7 January 2021

Topological characteristics of helical repeat proteins

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7 January 2021

Phosphorylation of Ser2078 modulates the Notch2 function in 32D cell differentiation

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7 January 2021

Signalling downstream of activated mammalian Notch

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7 January 2021

Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line

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7 January 2021

A histone deacetylase corepressor complex regulates the Notch signal transduction pathway

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7 January 2021

Molecular basis of loss-of-function mutations in the glp-1 gene of Caenorhabditis elegans

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7 January 2021

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7 January 2021

Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region

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7 January 2021

Further evidence for function of the Drosophila Notch protein as a transmembrane receptor

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7 January 2021

Notch and cancer: best to avoid the ups and downs.

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7 January 2021

Notch signaling: from the outside in

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7 January 2021

Notch signaling as a therapeutic target

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7 January 2021

Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex

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7 January 2021

Notch1 functions as a tumor suppressor in mouse skin

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7 January 2021

p300 acts as a transcriptional coactivator for mammalian Notch-1

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7 January 2021

LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway

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7 January 2021

The structure of a Ca2+-binding epidermal growth factor-like domain: Its role in protein-protein interactions

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7 January 2021

The ankyrin repeat: a diversity of interactions on a common structural framework

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7 January 2021

Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)

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7 January 2021

Stability and folding of the tumour suppressor protein p16

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7 January 2021

Sequential unfolding of ankyrin repeats in tumor suppressor p16

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7 January 2021

The N- and C-terminal regions of RBP-J interact with the ankyrin repeats of Notch1 RAMIC to activate transcription

1 reference

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7 January 2021

Tumor suppressor p16INK4A: structural characterization of wild-type and mutant proteins by NMR and circular dichroism

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7 January 2021

Nuclear magnetic resonance structure of a prototype Lin12-Notch repeat module from human Notch1

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7 January 2021

p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro

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7 January 2021

Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats

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7 January 2021

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

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7 January 2021

Structural consequences of tumor-derived mutations in p16INK4a probed by limited proteolysis

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7 January 2021

Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex

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7 January 2021

SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function

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7 January 2021

Studies of the ankyrin repeats of the Drosophila melanogaster Notch receptor. 1. Solution conformational and hydrodynamic properties

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7 January 2021

Studies of the ankyrin repeats of the Drosophila melanogaster Notch receptor. 2. Solution stability and cooperativity of unfolding

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7 January 2021

Structure and stability of the ankyrin domain of the Drosophila Notch receptor

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7 January 2021

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Identifiers

DOI

1 reference

27 June 2017

1 reference