(Q30936130)

27 June 2017

title

Discovering novel ligands for macromolecules using X-ray crystallographic screening (English)

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27 June 2017

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Nienaber VL

1

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27 June 2017

Richardson PL

2

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27 June 2017

Klighofer V

3

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27 June 2017

Bouska JJ

4

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27 June 2017

Giranda VL

5

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Greer J

6

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27 June 2017

publication date

1 October 2000

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27 June 2017

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27 June 2017

volume

18

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27 June 2017

issue

10

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27 June 2017

page(s)

1105-1108

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High-throughput and ultra-high-throughput screening: solution- and cell-based approaches

27 June 2017

cites work

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Structure-based drug design: progress, results and challenges

21 January 2018

1 reference

Serendipity meets precision: the integration of structure-based drug design and combinatorial chemistry for efficient drug discovery

21 January 2018

1 reference

Structure-based strategies for drug design and discovery

21 January 2018

1 reference

Discovering high-affinity ligands for proteins: SAR by NMR

21 January 2018

1 reference

The SHAPES strategy: an NMR-based approach for lead generation in drug discovery.

21 January 2018

1 reference

A computational procedure for determining energetically favorable binding sites on biologically important macromolecules

21 January 2018

1 reference

In search of new lead compounds for trypanosomiasis drug design: a protein structure-based linked-fragment approach.

21 January 2018

1 reference

Automated crystal mounting and data collection for protein crystallography

21 January 2018

1 reference

Re-engineering of human urokinase provides a system for structure-based drug design at high resolution and reveals a novel structural subsite

21 January 2018

1 reference

Structure-directed discovery of potent non-peptidic inhibitors of human urokinase that access a novel binding subsite.

21 January 2018

1 reference

Protein engineering as a tool for crystallography.

21 January 2018

1 reference

21 January 2018

The Protein Data Bank

1 reference

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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Using Electrospray Ionization FTICR Mass Spectrometry To Study Competitive Binding of Inhibitors to Carbonic Anhydrase

21 January 2018

1 reference

Physiological consequences of loss of plasminogen activator gene function in mice

21 January 2018

1 reference

Multiple copy simultaneous search and construction of ligands in binding sites: application to inhibitors of HIV-1 aspartic proteinase

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/80319

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27 June 2017

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