(Q30980343)

27 June 2017

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title

Dose-response modeling of in vivo genotoxicity data for use in risk assessment: some approaches illustrated by an analysis of acrylamide (English)

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27 June 2017

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Bruce Allen

1

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27 June 2017

Errol Zeiger

2

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27 June 2017

Greg Lawrence

3

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27 June 2017

Marvin Friedman

4

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27 June 2017

Annette Shipp

5

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27 June 2017

language of work or name

English

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publication date

8 December 2004

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Regulatory Toxicology and Pharmacology

27 June 2017

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27 June 2017

41

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27 June 2017

1

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27 June 2017

6-27

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Clastogenic effects of acrylamide in mouse bone marrow cells.

27 June 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Dose-response assessment for developmental toxicity. II. Comparison of generic benchmark dose estimates with no observed adverse effect levels.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Mutagenicity test schemes and guidelines: U.S. EPA Office of Pollution Prevention and Toxics and Office of Pesticide Programs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

The effects of acrylamide on mouse germ-line and somatic cell chromosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Cytogenetic effects of acrylamide in the bone marrow of mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Activity of acrylamide in single-, double-, and triple-dose mouse bone marrow micronucleus assays

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Acrylamide: a review of its genotoxicity and an assessment of heritable genetic risk.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

A Lifetime Oncogenicity Study in Rats with Acrylamide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Chronic toxicity and oncogenicity study on acrylamide incorporated in the drinking water of Fischer 344 rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Mutagenic activity of acrylamide in eukaryotic systems but not in bacteria.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

The impact of litter effects on dose-response modeling in teratology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Rat two-generation reproduction and dominant lethal study of acrylamide in drinking water

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

394: The Analysis of Binary Responses from Toxicological Experiments Involving Reproduction and Teratogenicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

The dose-response relationship at very low doses of acrylamide is linear in the flow cytometer-based mouse micronucleus assay

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Dose response for heritable translocations induced by acrylamide in spermatids of mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

1-Aminobenzotriazole inhibits acrylamide-induced dominant lethal effects in spermatids of male mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Flow cytometric detection of micronuclei induced by chemicals in poly- and normochromatic erythrocytes of mouse peripheral blood

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Kinetochore-staining of spermatid micronuclei: studies of mice treated with X-radiation or acrylamide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Induction of micronuclei in bone marrow and sperm head abnormalities after combined exposure of mice to low doses of X-rays and acrylamide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Induction of dominant lethal mutations by combined X-ray-acrylamide treatment in male mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Acrylamide: Dermal exposure produces genetic damage in male mouse germ cells*1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Reevaluation of the induction of specific-locus mutations in spermatogonia of the mouse by acrylamide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Induction of hypoploidy and cell cycle delay by acrylamide in somatic and germinal cells of male mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Acrylamide causes preimplantation abnormalities in embryos and induces chromatin-adducts in male germ cells of mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Detection of chemical mutagens using Muta Mouse: a transgenic mouse model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Cytogenetic studies of ethyl acrylate using C57BL/6 mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Somatic and germ cell mutagenesis in lambda lacZ transgenic mice treated with acrylamide or ethylnitrosourea.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Concurrent analysis of cytogenetic damage in vivo: A multiple endpoint‐multiple tissue approach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

The spirmatid micronucleus test with the dissection technique detects the germ cell mutagenicity of acrylamide in rat meiotic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Induction of chromosomal aberrations in mouse zygotes by acrylamide treatment of male germ cells and their correlation with dominant lethality and heritable translocations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Mutagenic and teratogenic effects of acrylamide in the mammalian spot test

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Acrylamide-induced chromosomal damage in male mouse germ cells detected by cytogenetic analysis of one-cell zygotes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Hemoglobin adducts and micronucleus frequencies in mouse and rat after acrylamide or N-methylolacrylamide treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Induction of specific-locus mutations in male germ cells of the mouse by acrylamide monomer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Weak genotoxicity of acrylamide on premeiotic and somatic cells on the mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Detection of aneuploidy by multicolor FISH in mouse sperm after in vivo treatment with acrylamide, colchicine, diazepam or thiabendazole.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Dominant lethal effects of acrylamide in male mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Acrylamide: induction of heritable translocation in male mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Dominant lethal effects of subchronic acrylamide administration in the male Long-Evans rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Factors associated with reduced fertility and implantation rates in females mated to acrylamide-treated rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Relationship between acrylamide reproductive and neurotoxicity in male rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Comparison of the dominant lethal effects of acrylonitrile and acrylamide in male Fischer 344 rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

Increased frequencies of micronuclei in early spermatids of rats following exposure of young primary spermatocytes to acrylamide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2004.09.006

10.1016/J.YRTPH.2004.09.006

7 January 2021

Identifiers

DOI

1 reference

27 June 2017

1 reference