(Q31004131)

28 June 2017

title

High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans (English)

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28 June 2017

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Andrew M Goetze

1

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28 June 2017

Y Diana Liu

2

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28 June 2017

Zhongqi Zhang

3

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28 June 2017

Bhavana Shah

4

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28 June 2017

Edward Lee

5

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28 June 2017

Pavel V Bondarenko

6

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28 June 2017

Gregory C Flynn

7

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28 June 2017

publication date

18 March 2011

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28 June 2017

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28 June 2017

volume

21

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28 June 2017

issue

7

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28 June 2017

page(s)

949-959

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From pattern recognition receptor to regulator of homeostasis: the double-faced macrophage mannose receptor

28 June 2017

cites work

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

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The effect of Fc glycan forms on human IgG2 antibody clearance in humans

21 January 2018

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Naturally occurring glycan forms of human immunoglobulins G1 and G2.

21 January 2018

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Assessing monoclonal antibody product quality attribute criticality through clinical studies

21 January 2018

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Direct identification and quantification of aspartyl succinimide in an IgG2 mAb by RapiGest assisted digestion

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

Glycosylation of recombinant antibody therapeutics

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

Selective clearance of glycoforms of a complex glycoprotein pharmaceutical caused by terminal N-acetylglucosamine is similar in humans and cynomolgus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

Capillary electrophoresis with laser-induced fluorescence detection for detailed studies on N-linked oligosaccharide profile of therapeutic recombinant monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

Clearance mechanism of a mannosylated antibody-enzyme fusion protein used in experimental cancer therapy

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

Mannose receptor-mediated regulation of serum glycoprotein homeostasis

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

Human IgG2 antibody disulfide rearrangement in vivo

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

The influence of glycosylation on the thermal stability and effector function expression of human IgG1-Fc: properties of a series of truncated glycoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

Fc receptors and their interactions with immunoglobulins

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

Reversed-phase liquid chromatography/mass spectrometry analysis of reduced monoclonal antibodies in pharmaceutics

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

FcRn: the neonatal Fc receptor comes of age.

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

Downstream processing of monoclonal antibodies--application of platform approaches

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

The mannose receptor and other macrophage lectins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

Effect of altered CH2-associated carbohydrate structure on the functional properties and in vivo fate of chimeric mouse-human immunoglobulin G1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

Enzyme-friendly, mass spectrometry-compatible surfactant for in-solution enzymatic digestion of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

Large-scale identification and quantification of covalent modifications in therapeutic proteins

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWR027

21 January 2018

Identifiers

DOI

10.1093/GLYCOB/CWR027

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28 June 2017

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