(Q31049371)

28 June 2017

Glyoxalase II of African trypanosomes is trypanothione-dependent (English)

1 reference

28 June 2017

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Thorsten Irsch

1

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PubMed ID

14976196

28 June 2017

R Luise Krauth-Siegel

series ordinal

2

1 reference

PubMed ID

14976196

28 June 2017

language of work or name

English

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publication date

19 February 2004

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Journal of Biological Chemistry

28 June 2017

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28 June 2017

279

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28 June 2017

22209-22217

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28 June 2017

21

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Glutathione-dependent detoxification of alpha-oxoaldehydes by the glyoxalase system: involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors.

28 June 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Metabolism and functions of trypanothione in the Kinetoplastida

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Thiol-based redox metabolism of protozoan parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Cloning, sequencing, overproduction and purification of trypanothione reductase from Trypanosoma cruzi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

21 January 2018

Tissue sulfhydryl groups

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Molecular cloning, heterologous expression, and characterization of human glyoxalase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Preparation and assay of glutathione thiol esters. Survey of human liver glutathione thiol esterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

A sensitive equilibrium-based assay for D-lactate using D-lactate dehydrogenase: application to penicillin-binding protein/DD-carboxypeptidase activity assays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Molecular cloning and characterization of the thiolesterase glyoxalase II from Arabidopsis thaliana

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Stereospecificity of substrate usage by glyoxalase 1: nuclear magnetic resonance studies of kinetics and hemithioacetal substrate conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Crystal structure of human glyoxalase I--evidence for gene duplication and 3D domain swapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Caution: the glycylmethyl and glycylethyl esters of glutathione are substrates for glyoxalase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Purification and characterization of S-2-hydroxyacylglutathione hydrolase (glyoxalase II) from human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Diffusion-dependent rates for the hydrolysis reaction catalyzed by glyoxalase II from rat erythrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Accumulation of a GPI-anchored protein at the cell surface requires sorting at multiple intracellular levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Purification, morphometric analysis, and characterization of the glycosomes (microbodies) of the protozoan hemoflagellate Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

The Parasite-Specific Trypanothione Metabolism of Trypanosoma and Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

A second class of peroxidases linked to the trypanothione metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Methylglyoxal production in bacteria: suicide or survival?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

In situ kinetic analysis of glyoxalase I and glyoxalase II in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Isolation of glyoxalase II from two different compartments of rat liver mitochondria. Kinetic and immunochemical characterization of the enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Flexible metal binding of the metallo-beta-lactamase domain: glyoxalase II incorporates iron, manganese, and zinc in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

D-lactate production by Leishmania braziliensis through the glyoxalase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Products of Leishmania braziliensis glucose catabolism: release of D-lactate and, under anaerobic conditions, glycerol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

D-Lactate transport and metabolism in rat liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Functional and physicochemical characterization of the thioredoxin system in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Oxidative damage of DNA induced by methylglyoxal in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Anti-glycation defences in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Heterologous expression, purification, and kinetic comparison of the cytoplasmic and mitochondrial glyoxalase II enzymes, Glo2p and Glo4p, from Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Molecular characterization of glyoxalase II from Arabidopsis thaliana.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Metabolic compartmentation in African trypanosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Increased formation of methylglyoxal and protein glycation, oxidation and nitrosation in triosephosphate isomerase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

Antimalarial activity in vitro of the glyoxalase I inhibitor diester, S-p-bromobenzylglutathione diethyl ester.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401240200

21 January 2018

Identifiers

DOI

10.1074/JBC.M401240200

1 reference

28 June 2017

1 reference

PubMed ID

14976196