(Q31153995)

21 August 2017

BEX1 promotes imatinib-induced apoptosis by binding to and antagonizing BCL-2 (English)

1 reference

21 August 2017

Qian Xiao

1

1 reference

21 August 2017

Yeting Hu

2

1 reference

21 August 2017

Yue Liu

3

1 reference

21 August 2017

Zhanhuai Wang

4

1 reference

21 August 2017

Haitao Geng

5

1 reference

21 August 2017

Lifeng Hu

6

1 reference

21 August 2017

Dengyong Xu

7

1 reference

21 August 2017

Ke Wang

8

1 reference

21 August 2017

Lei Zheng

9

1 reference

21 August 2017

Shu Zheng

10

1 reference

21 August 2017

Kefeng Ding

11

1 reference

21 August 2017

language of work or name

English

0 references

publication date

13 March 2014

1 reference

21 August 2017

1 reference

21 August 2017

9

1 reference

21 August 2017

3

1 reference

21 August 2017

e91782

1 reference

Creative Commons Attribution 4.0 International

21 August 2017

start time

13 March 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3953594/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Glucocorticoid resistance in chronic lymphocytic leukaemia is associated with a failure of upregulated Bim/Bcl-2 complexes to activate Bax and Bak.

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Tyrosine kinase inhibitors in acute and chronic leukemias

21 June 2018

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Is there something other than imatinib mesilate in therapeutic options for GIST?

21 June 2018

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Mechanisms and novel approaches in overriding tyrosine kinase inhibitor resistance in chronic myeloid leukemia

21 June 2018

1 reference

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The role of protein phosphorylation in therapy resistance and disease progression in chronic myelogenous leukemia.

21 June 2018

1 reference

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Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis

21 June 2018

1 reference

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The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy

21 June 2018

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Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX

21 June 2018

1 reference

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cIAP1 cooperatively inhibits procaspase-3 activation by the caspase-9 apoptosome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

BEX2 has a functional interplay with c-Jun/JNK and p65/RelA in breast cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

Role for the proapoptotic factor BIM in mediating imatinib-induced apoptosis in a c-KIT-dependent gastrointestinal stromal tumor cell line

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

BEX2 regulates mitochondrial apoptosis and G1 cell cycle in breast cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

Inhibition of apoptosis by downregulation of hBex1, a novel mechanism, contributes to the chemoresistance of Bcr/Abl+ leukemic cells

21 June 2018

1 reference

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Overcoming kinase resistance in chronic myeloid leukemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

BEX2 is overexpressed in a subset of primary breast cancers and mediates nerve growth factor/nuclear factor-kappaB inhibition of apoptosis in breast cancer cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

Loss of p53 impedes the antileukemic response to BCR-ABL inhibition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

BCL2 family of apoptosis-related genes: functions and clinical implications in cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

Characterization of the Bex gene family in humans, mice, and rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

Identification of members of the Bex gene family as olfactory marker protein (OMP) binding partners

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

Cloning and expression pattern of a spermatogenesis-related gene, BEX1, mapped to chromosome Xq22.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

21 June 2018

1 reference

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Role of Bcl-2 and its post-transcriptional modification in response to antitumor therapy.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3953594

Mechanisms of Resistance to Imatinib and Second-Generation Tyrosine Inhibitors in Chronic Myeloid Leukemia.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0091782

Compensatory PI3-kinase/Akt/mTor activation regulates imatinib resistance development

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0091782

Genetic analysis of chemoresistance in primary murine lymphomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0091782

Adaptive secretion of granulocyte-macrophage colony-stimulating factor (GM-CSF) mediates imatinib and nilotinib resistance in BCR/ABL+ progenitors via JAK-2/STAT-5 pathway activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0091782

Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24626299

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0091782

1 reference

21 August 2017

0 references

1 reference

21 August 2017

PubMed publication ID

24626299

1 reference