(Q31390340)

1 July 2017

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title

Role of DNA repair in carcinogen-induced ras mutation (English)

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1 July 2017

Engelbergs J

1

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1 July 2017

Thomale J

series ordinal

2

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1 July 2017

Rajewsky MF

series ordinal

3

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1 July 2017

language of work or name

English

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publication date

1 May 2000

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1 July 2017

15

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published in

Mutation Research

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1 July 2017

450

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1 July 2017

1-2

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1 July 2017

139-153

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Cancer-susceptibility genes. Gatekeepers and caretakers

1 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Apurinic sites as mutagenic intermediates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

DNA-replication fidelity, mismatch repair and genome instability in cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Mutagenic and epigenetic effects of DNA methylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Biochemistry of Oxidative Stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Nitrosated peptides and polyamines as endogenous mutagens in O6-alkylguanine-DNA alkyltransferase deficient cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Excision repair invades the territory of mismatch repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Involvement of nucleotide-excision repair in msh2 pms1-independent mismatch repair.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Preferential and strand-specific DNA repair of (6-4) photoproducts detected by a photochemical method in the hamster DHFR gene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

BRCA1 required for transcription-coupled repair of oxidative DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Transcription-coupled repair of psoralen cross-links but not monoadducts in Chinese hamster ovary cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Site-specific rates of excision repair of benzo[a]pyrene diol epoxide adducts in the hypoxanthine phosphoribosyltransferase gene of human fibroblasts: correlation with mutation spectra

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Functional nucleotide excision repair is required for the preferential removal of N-ethylpurines from the transcribed strand of the dihydrofolate reductase gene of Chinese hamster ovary cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Increased gene-specific repair of cisplatin interstrand cross-links in cisplatin-resistant human ovarian cancer cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Human nucleotide excision repair syndromes: molecular clues to unexpected intricacies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Sunlight and skin cancer: another link revealed

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Xeroderma pigmentosum and the role of UV-induced DNA damage in skin cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Eukaryotic mismatch repair: an update

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Molecular and cellular mechanisms associated with pulse-carcinogenesis in the rat nerbous system by ethyinitrosourea: ethylation of nucleic acids and elimination rates of ethylated bases from the DNA of different tissues.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Oxygens in DNA are main targets for ethylnitrosourea in normal and xeroderma pigmentosum fibroblasts and fetal rat brain cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Regulation and expression of the adaptive response to alkylating agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Enzymatic elimination of O6-ethylguanine and stability of O4-ethylthymine in the DNA of malignant neural cell lines exposed to N-ethyl-N-nitrosourea in culture.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Enzymatic elimination of O6-ethylguanine from the DNA of ethylnitrosourea-exposed normal and malignant rat brain cells grown under cell cultureversus in vivo conditions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Persistence of O 6-Ethylguanine in Rat-Brain DNA: Correlation with Nervous System-Specific Carcinogenesis by Ethylnitrosourea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Alkylation of deoxyribonucleic acid in vivo in various organs of C57BL mice by the carcinogens N-methyl-N-nitrosourea, N-ethyl-N-nitrosourea and ethyl methanesulphonate in relation to induction of thymic lymphoma. Some applications of high-pressure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

DNA methyl-adduct dosimetry and O6-alkylguanine-DNA alkyl transferase activity determinations in rat mammary carcinogenesis by procarbazine and N-methylnitrosourea.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Repair of O6-ethylguanine in DNA protects rat 208F cells from tumorigenic conversion by N-ethyl-N-nitrosourea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

The prevention of thymic lymphomas in transgenic mice by human O6-alkylguanine-DNA alkyltransferase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

The immature thymocyte is protected from N-methylnitrosourea-induced lymphoma by the human MGMT-CD2 transgene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Mice over-expressing human O6 alkylguanine-DNA alkyltransferase selectively reduce O6 methylguanine mediated carcinogenic mutations to threshold levels after N-methyl-N-nitrosourea.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Reduced lung tumorigenesis in human methylguanine DNA--methyltransferase transgenic mice achieved by expression of transgene within the target cell.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Fast repair of O6-ethylguanine, but not O6-methylguanine, in transcribed genes prevents mutation of H-ras in rat mammary tumorigenesis induced by ethylnitrosourea in place of methylnitrosourea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Effect of carcinogen dose and age at administration on induction of mammary carcinogenesis by 1-methyl-1-nitrosourea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Activation of ras oncogenes preceding the onset of neoplasia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Apoptosis: Ras to the rescue in the fly eye.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Immuno-slot-blot: a highly sensitive immunoassay for the quantitation of carcinogen-modified nucleosides in DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Monoclonal antibody-based, selective isolation of DNA fragments containing an alkylated base to be quantified in defined gene sequences

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Implication of localization of human DNA repair enzyme O6-methylguanine-DNA methyltransferase at active transcription sites in transcription-repair coupling of the mutagenic O6-methylguanine lesion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Mechanism of inactivation of human O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Nucleotide excision repair modulates the cytotoxic and mutagenic effects of N-n-butyl-N-nitrosourea in cultured mammalian cells as well as in mouse splenocytes in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Site-specific mutagenesis by O6-alkylguanines located in the chromosomes of mammalian cells: influence of the mammalian O6-alkylguanine-DNA alkyltransferase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Induction of the Escherichia coli lactose operon selectively increases repair of its transcribed DNA strand

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Action of DNA repair endonuclease ERCC1/XPF in living cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Alkylation damage, DNA repair and mutagenesis in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage: version 3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Both O4-methylthymine and O4-ethylthymine preferentially form alkyl T.G pairs that do not block in vitro replication in a defined sequence.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Mutagenesis by apurinic/apyrimidinic sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Coding properties of a unique apurinic/apyrimidinic site replicated in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

In vitroDNA replication implicates O2-ethyldeoxythymidine in transversion mutagenesis by ethylating agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

O4-ethyldeoxythymidine, but not O6-ethyldeoxyguanosine, accumulates in hepatocyte DNA of rats exposed continuously to diethylnitrosamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

O2- and O4-ethylthymine and the ethylphosphotriester dTp(Et)dT are highly persistent DNA modifications in slowly dividing tissues of the ethylnitrosourea-treated rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Specific patterns of oncogene activation in transplacentally induced tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

N-methylnitrosourea-induced Ki-ras codon 12 mutations: early events in mouse thymic lymphomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

K-ras codon 12 and 61 point mutations in bromodeoxyuridine- and N-nitrosomethylurea-induced rat renal mesenchymal tumors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Ki-ras mutations in spontaneous and chemically induced renal tumors of the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Activated neu oncogene sequences in primary tumors of the peripheral nervous system induced in rats by transplacental exposure to ethylnitrosourea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Early mutation of the neu (erbB-2) gene during ethylnitrosourea-induced oncogenesis in the rat Schwann cell lineage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Mutagenesis of the K-ras protooncogene in mouse lung tumors induced by N-ethyl-N-nitrosourea or N-nitrosodiethylamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Detection of activated proto-oncogenes in N-nitrosodiethylamine-induced liver tumors: a comparison between B6C3F1 mice and Fischer 344 rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Polycyclic aromatic hydrocarbons: correlations between DNA adducts and ras oncogene mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Comparison of O6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

N-Ethyl-N-nitrosourea induces mammary cancers in the pituitary-isografted mouse which are histologically and genotypically distinct from those induced by N-methyl-N-nitrosourea.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

A prospective study of reproductive factors and breast cancer. I. Parity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Prevention of mammary carcinogenesis in rats by pregnancy: effect of full-term and interrupted pregnancy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

O(6)-methyldeoxyguanosine in oesophageal DNA among individuals at high risk of oesophageal cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

O6-methylguanine in blood leucocyte DNA: an association with the geographic prevalence of gastric cancer and with low levels of serum pepsinogen A, a marker of severe chronic atrophic gastritis. The EUROGAST Study Group

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Deficient DNA repair capacity, a predisposing factor in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

DNA repair proficiency: potential susceptiblity factor for breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Environment and cancer: who are susceptible?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

DNA repair: enzymatic mechanisms and relevance to drug response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Repair of O6-alkylguanines in the nuclear DNA of human lymphocytes and leukaemic cells: analysis at the single-cell level

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

Intragenomic heterogeneity of DNA damage formation and repair: a review of cellular responses to covalent drug DNA interaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2800%2900021-X

10.1016/S0027-5107(00)00021-X

7 January 2021

Identifiers

DOI

1 reference

1 July 2017

1 reference