(Q31395542)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854442%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854442%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

author name string

M J Peck

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854442%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

B J Van Keulen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854442%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

A Jorritsma

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854442%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

P R Clapham

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854442%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

T J Williams

7

1 reference

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7 November 2019

J E Pease

8

1 reference

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7 November 2019

language of work or name

English

0 references

publication date

1 August 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854442%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

7 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854442%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

volume

275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854442%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

page(s)

25985-25992

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854442%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

issue

34

1 reference

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Eosinophilic Inflammation in Asthma

7 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Chemokines--chemotactic cytokines that mediate inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Eotaxin: cloning of an eosinophil chemoattractant cytokine and increased mRNA expression in allergen-challenged guinea-pig lungs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Conserved structure and tissue expression of rat eotaxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Kinetics of eotaxin generation and its relationship to eosinophil accumulation in allergic airways disease: analysis in a guinea pig model in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Eotaxin protein and gene expression in guinea-pig lungs: constitutive expression and upregulation after allergen challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Mechanisms of acute eosinophil mobilization from the bone marrow stimulated by interleukin 5: the role of specific adhesion molecules and phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

T cell-dependent regulation of eotaxin in antigen-induced pulmonary eosinophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Interleukin-13: central mediator of allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Cloning and functional expression of a human eosinophil CC chemokine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Identification of a mouse eosinophil receptor for the CC chemokine eotaxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

The N-terminal extracellular segments of the chemokine receptors CCR1 and CCR3 are determinants for MIP-1alpha and eotaxin binding, respectively, but a second domain is essential for efficient receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Establishment of a new system for determination of coreceptor usages of HIV based on the human glioma NP-2 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Chemoattractant receptor cross-desensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Determinants of HIV-1 coreceptor function on CC chemokine receptor 3. Importance of both extracellular and transmembrane/cytoplasmic regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Dynamical Instabilities and the Formation of Extrasolar Planetary Systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Identification and characterization of small molecule functional antagonists of the CCR1 chemokine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Chemokine receptor CCR3 function is highly dependent on local pH and ionic strength

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Differential activation of CC chemokine receptors by AOP-RANTES

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

CCR5 HIV-1 coreceptor activity. Role of cooperativity between residues in N-terminal extracellular and intracellular domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

The amino-terminal extracellular domain of the MCP-1 receptor, but not the RANTES/MIP-1alpha receptor, confers chemokine selectivity. Evidence for a two-step mechanism for MCP-1 receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

Two-site binding of C5a by its receptor: an alternative binding paradigm for G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

C5a receptor activation. Genetic identification of critical residues in four transmembrane helices

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M908864199

21 January 2018

Identifiers

DOI

10.1074/JBC.M908864199

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10854442%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference