(Q31442619)

English

Tyrosine 220 in the 5th transmembrane domain of the neuromedin B receptor is critical for the high selectivity of the peptoid antagonist PD168368.

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

Tyrosine 220 in the 5th transmembrane domain of the neuromedin B receptor is critical for the high selectivity of the peptoid antagonist PD168368. (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

transmembrane protein

0 references

author name string

Tokita K

1

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

Hocart SJ

2

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

Katsuno T

3

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

Mantey SA

4

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

Coy DH

5

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

Jensen RT

6

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

language of work or name

0 references

publication date

1 January 2001

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

276

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

495-504

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

The 'peptoid' approach to the design of non-peptide, small molecule agonists and antagonists of neuropeptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Second generation "peptoid" CCK-B receptor antagonists: identification and development of N-(adamantyloxycarbonyl)-alpha-methyl-(R)-tryptophan derivative (CI-1015) with an improved pharmacokinetic profile

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Peptoid CCK receptor antagonists: pharmacological evaluation of CCKA, CCKB and mixed CCKA/B receptor antagonists

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Cholecystokinin dipeptoid antagonists: design, synthesis, and anxiolytic profile of some novel CCK-A and CCK-B selective and mixed CCK-A/CCK-B antagonists

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Design, synthesis, and biological activities of potent and selective somatostatin analogues incorporating novel peptoid residues.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Use of a dipeptide chemical library in the development of non-peptide tachykinin NK3 receptor selective antagonists

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

A single amino acid of the cholecystokinin-B/gastrin receptor determines specificity for non-peptide antagonists

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Arginine 336 and asparagine 333 of the human cholecystokinin-A receptor binding site interact with the penultimate aspartic acid and the C-terminal amide of cholecystokinin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Separable Binding Sites for the Natural Agonist Endothelin-1 and the Non-Peptide Antagonist Bosentan on Human Endothelin-A Receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

G protein-coupled receptors. I. Diversity of receptor-ligand interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Mammalian bombesin receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Bombesin: central nervous system actions to affect the autonomic nervous system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Bombesin: potential integrative peptide for feeding and satiety

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Interaction of bombesin and related peptides with receptors on pancreatic acinar cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Role of neuromedin B in the control of the release of thyrotropin in the rat.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Bombesin, neuromedin C and neuromedin B given intrathecally facilitate the tail flick reflex in the rat

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

An immunomodulator used to protect young in the pouch of the Tammar wallaby, Macropus eugenii

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Characterization of bombesin receptors in peripheral contractile organs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Progress in the development of potent bombesin receptor antagonists

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

PD 176252--the first high affinity non-peptide gastrin-releasing peptide (BB2) receptor antagonist

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Discovery of a high affinity radioligand for the human orphan receptor, bombesin receptor subtype 3, which demonstrates that it has a unique pharmacology compared with other mammalian bombesin receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

A new model for calculating atomic charges in molecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Homology modeling, model and software evaluation: three related resources

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

WHAT IF: a molecular modeling and drug design program

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Pharmacologic and therapeutic applications of alpha 2-adrenoceptor subtypes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Mutational analysis of muscarinic acetylcholine receptors: structural basis of ligand/receptor/G protein interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Delineation of a region in the B2 bradykinin receptor that is essential for high-affinity agonist binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Role of the extracellular domains of the cholecystokinin receptor in agonist binding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Mutation of aspartate residues in the third extracellular loop of the rat B2 bradykinin receptor decreases affinity for bradykinin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Modeling the G-protein-coupled neuropeptide Y Y1 receptor agonist and antagonist binding sites.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Studies on mu and delta opioid receptor selectivity utilizing chimeric and site-mutagenized receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Different binding epitopes on the NK1 receptor for substance P and non-peptide antagonist.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Cation-pi interactions in aromatics of biological and medicinal interest: electrostatic potential surfaces as a useful qualitative guide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Critical Role of a Conserved Intramembrane Tyrosine Residue in Angiotensin II Receptor Activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Rational design of high affinity tachykinin NK2 receptor antagonists

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

In vivo and in vitro pharmacology of SR 48,968, a non-peptide tachykinin NK2 receptor antagonist

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Lysine 182 of endothelin B receptor modulates agonist selectivity and antagonist affinity: evidence for the overlap of peptide and non-peptide ligand binding sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Bombesin: action on gut hormones and calcium in man

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Stimulation of natural killer and antibody-dependent cellular cytotoxicity activities in mouse leukocytes by bombesin, gastrin-releasing peptide and neuromedin C: involvement of cyclic AMP, inositol 1,4,5-trisphosphate and protein kinase C

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Anti-bombesin monoclonal antibodies modulate fetal mouse lung growth and maturation in utero and in organ cultures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Bombesin and bradykinin increase inositol phosphates and cytosolic free Ca2+, and stimulate DNA synthesis in human endometrial stromal cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Distinct receptors mediate gastrin-releasing peptide and neuromedin beta-induced delay of gastric of liquids in rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Different types of bombesin receptors on neurons in the dorsal raphe nucleus and the rostral hypothalamus in rat brain slices in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

A new approach to docking in the beta 2-adrenergic receptor that exploits the domain structure of G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Identification of a key region of kinin B(1) receptor for high affinity binding of peptide antagonists

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

The role of the Val353 residue in antagonist binding to rat CCK-B receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Site-directed mutagenesis on the m2 muscarinic acetylcholine receptor: the significance of Tyr403 in the binding of agonists and functional coupling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Identification of Domains Conferring Ligand Binding Specificity to the Prostanoid Receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

The role of the cholecystokinin-B/gastrin receptor transmembrane domains in determining affinity for subtype-selective ligands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Relationships between apparent binding energies measured in site-directed mutagenesis experiments and energetics of binding and catalysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006059200

21 January 2018

Identifiers

10.1074/JBC.M006059200

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 July 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q31442619&oldid=1607174242"