(Q31473336)

2 July 2017

Ligand-independent dimerization and activation of the oncogenic Xmrk receptor by two mutations in the extracellular domain (English)

1 reference

2 July 2017

A Gómez

1

1 reference

2 July 2017

C Wellbrock

2

1 reference

2 July 2017

H Gutbrod

3

1 reference

2 July 2017

N Dimitrijevic

4

1 reference

2 July 2017

M Schartl

5

1 reference

2 July 2017

language of work or name

English

0 references

publication date

18 October 2000

1 reference

Journal of Biological Chemistry

2 July 2017

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2 July 2017

276

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2 July 2017

5

1 reference

2 July 2017

3333-3340

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Signal transduction by receptors with tyrosine kinase activity

2 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Growth factors and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Oncogenic activation of tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Platyfish and swordtails: a genetic system for the analysis of molecular mechanisms in tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Signalling by the oncogenic receptor tyrosine kinase Xmrk leads to activation of STAT5 in Xiphophorus melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

High-efficiency transformation of mammalian cells by plasmid DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Receptor tyrosine kinase Xmrk mediates proliferation in Xiphophorus melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Ligand-independent activation of fibroblast growth factor receptors by point mutations in the extracellular, transmembrane, and kinase domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

A point mutation in the extracellular domain of the human CSF-1 receptor (c-fms proto-oncogene product) activates its transforming potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Expression of wild-type and mutant forms of influenza hemagglutinin: the role of folding in intracellular transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Ligand stimulation of a Ret chimeric receptor carrying the activating mutation responsible for the multiple endocrine neoplasia type 2B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Multiple binding sites in the growth factor receptor Xmrk mediate binding to p59fyn, GRB2 and Shc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Oncogenic mutation in the Kit receptor tyrosine kinase alters substrate specificity and induces degradation of the protein tyrosine phosphatase SHP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

The multiple endocrine neoplasia type 2B point mutation alters long-term regulation and enhances the transforming capacity of the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Ligand-independent activation of fibroblast growth factor receptor-2 by carboxyl terminal alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Disulfide bond structure of human epidermal growth factor receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Dual effect on the RET receptor of MEN 2 mutations affecting specific extracytoplasmic cysteines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

The Glu632-Leu633 deletion in cysteine rich domain of Ret induces constitutive dimerization and alters the processing of the receptor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

FGFR activation in skeletal disorders: too much of a good thing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

A splicing variant of the RON transcript induces constitutive tyrosine kinase activity and an invasive phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Homodimerization and constitutive activation of the erythropoietin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Mutations affecting conserved cysteine residues within the extracellular domain of Neu promote receptor dimerization and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

A point mutation in the extracellular domain activates LET-23, the Caenorhabditis elegans epidermal growth factor receptor homolog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

RTK mutations and human syndromeswhen good receptors turn bad.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Activation of Neu (ErbB-2) mediated by disulfide bond-induced dimerization reveals a receptor tyrosine kinase dimer interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Activating mutations in the extracellular domain of the fibroblast growth factor receptor 2 function by disruption of the disulfide bond in the third immunoglobulin-like domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

A novel case of multiple endocrine neoplasia type 2A associated with two de novo mutations of the RET protooncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Molecular cloning and expression of an additional epidermal growth factor receptor-related gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Expression of the epidermal growth factor receptor gene is regulated in mouse blastocysts during delayed implantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

All autophosphorylation sites of epidermal growth factor (EGF) receptor and HER2/neu are located in their carboxyl-terminal tails. Identification of a novel site in EGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

The Drosophila EGF receptor gene homolog: conservation of both hormone binding and kinase domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Exposed Thiols Confer Localization in the Endoplasmic Reticulum by Retention Rather than Retrieval

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Activation of the Xmrk proto-oncogene of Xiphophorus by overexpression and mutational alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

Amplification of a long terminal repeat-like element on the Y chromosome of the platyfish, Xiphophorus maculatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006574200

21 January 2018

Identifiers

DOI

10.1074/JBC.M006574200

1 reference

2 July 2017

1 reference