(Q31655353)

3 July 2017

Repression of human reduced folate carrier gene expression by wild type p53. (English)

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3 July 2017

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B C Ding

1

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3 July 2017

J R Whetstine

2

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3 July 2017

T L Witt

3

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3 July 2017

J D Schuetz

4

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3 July 2017

L H Matherly

5

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3 July 2017

language of work or name

English

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publication date

5 December 2000

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Journal of Biological Chemistry

3 July 2017

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3 July 2017

276

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3 July 2017

12

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3 July 2017

8713-8719

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3 July 2017

p53: puzzle and paradigm

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p53, the cellular gatekeeper for growth and division

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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WAF1, a potential mediator of p53 tumor suppression

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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Induction of the growth inhibitor IGF-binding protein 3 by p53

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Identification of p53 as a sequence-specific DNA-binding protein

21 January 2018

1 reference

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Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element

21 January 2018

1 reference

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p53 regulates the minimal promoter of the human topoisomerase IIalpha gene

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Inhibition of DNA topoisomerase II alpha gene expression by the p53 tumor suppressor

21 January 2018

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Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

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p53-dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents

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Inhibition of mouse thymidylate synthase promoter activity by the wild-type p53 tumor suppressor protein

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Wild-type p53 binds to the TATA-binding protein and represses transcription

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1 reference

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Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

21 January 2018

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Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction.

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The cellular pharmacology of methotrexate

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Transcript heterogeneity of the human reduced folate carrier results from the use of multiple promoters and variable splicing of alternative upstream exons

21 January 2018

1 reference

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Structural analysis of the human RFC-1 gene encoding a folate transporter reveals multiple promoters and alternatively spliced transcripts with 5' end heterogeneity

21 January 2018

1 reference

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The basal promoters for the human reduced folate carrier gene are regulated by a GC-box and a cAMP-response element/AP-1-like element. Basis for tissue-specific gene expression

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Suppression of human colorectal carcinoma cell growth by wild-type p53

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p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

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A transcriptionally active DNA-binding site for human p53 protein complexes

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Transcriptional activation by tetracyclines in mammalian cells

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier.

21 January 2018

1 reference

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Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells

21 January 2018

1 reference

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Rapid, simultaneous measurement of DNA, protein, and cell volume in single cells from large mammalian cell populations

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Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines.

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The role of E2F in the mammalian cell cycle

21 January 2018

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Growth/cell cycle regulation of Sp1 phosphorylation

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1 reference

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O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions

21 January 2018

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Regulation of the human hsp70 promoter by p53

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p53 status and the efficacy of cancer therapy in vivo

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Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

21 January 2018

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An inhibitor of glycinamide ribonucleotide formyltransferase is selectively cytotoxic to cells that lack a functional G1 checkpoint

21 January 2018

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Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M005248200

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3 July 2017

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