(Q31859902)

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Involvement of glutathione metabolism in the cytotoxicity of the phenethyl isothiocyanate and its cysteine conjugate to human leukaemia cells in vitro

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 July 2017

Involvement of glutathione metabolism in the cytotoxicity of the phenethyl isothiocyanate and its cysteine conjugate to human leukaemia cells in vitro (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

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author name string

Xu K

1

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Europe PubMed Central

PubMed publication ID

4 July 2017

Thornalley PJ

2

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4 July 2017

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publication date

1 January 2001

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Europe PubMed Central

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4 July 2017

Biochemical Pharmacology

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Europe PubMed Central

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4 July 2017

61

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Europe PubMed Central

PubMed publication ID

4 July 2017

2

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Europe PubMed Central

PubMed publication ID

4 July 2017

165-177

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Europe PubMed Central

PubMed publication ID

4 July 2017

Inhibition of rat liver cytochrome P450 isozymes by isothiocyanates and their conjugates: a structure-activity relationship study

1 reference

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Glutathione S-transferase subunit induction patterns of Brussels sprouts, allyl isothiocyanate and goitrin in rat liver and small intestinal mucosa: a new approach for the identification of inducing xenobiotics

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Phenylalkyl isothiocyanate-cysteine conjugates as glutathione S-transferase stimulating agents

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Inhibition of human leukaemia 60 cell growth by mercapturic acid metabolites of phenylethyl isothiocyanate

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Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro.

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Molecular mechanisms of c-Jun N-terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates

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Effect of phenethyl isothiocyanate on the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured rat lung tissue.

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Priming of human neutrophil functions by tumor necrosis factor: enhancement of superoxide anion generation, degranulation, and chemotaxis to chemoattractants C5a and F-Met-Leu-Phe

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Inhibition of proliferation of human promyelocytic leukaemia HL60 cells by S-d-lactoylglutathione in vitro

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Effect of methylglyoxal on human leukaemia 60 cell growth: Modification of DNA, G1 growth arrest and induction of apoptosis

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Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence

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Forward and reverse catalysis and product sequestration by human glutathione S-transferases in the reaction of GSH with dietary aralkyl isothiocyanates

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Non-oxidative loss of glutathione in apoptosis via GSH extrusion.

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Rapid and specific efflux of reduced glutathione during apoptosis induced by anti-Fas/APO-1 antibody

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Reduced glutathione esters--antidotes to toxicity. Cytotoxicity induced by hydrogen peroxide, 1-chloro-2,4-dinitrobenzene, and menadione in murine P388D1 macrophages in vitro

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Expression of the multidrug resistance-associated protein (MRP) mRNA and protein in normal peripheral blood and bone marrow haemopoietic cells

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Comparison of the delivery of reduced glutathione into P388D1 cells by reduced glutathione and its mono- and diethyl ester derivatives

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Characterization of quinone reductase, glutathione and glutathione S-transferase in human myeloid cell lines: induction by 1,2-dithiole-3-thione and effects on hydroquinone-induced cytotoxicity

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Glutathione S-transferases--biomarkers of cancer risk and chemopreventive response

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Macrophages regulate intracellular glutathione levels of lymphocytes. Evidence for an immunoregulatory role of cysteine

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Low membrane transport activity for cystine in resting and mitogenically stimulated human lymphocyte preparations and human T cell clones

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Expression of Bcl-2 increases intracellular glutathione by inhibiting methionine-dependent GSH efflux.

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BCL-2 family members and the mitochondria in apoptosis

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Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin

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Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation

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The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation

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The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents

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Activation of the c-Jun N-terminal kinase/stress-activated protein kinase pathway by overexpression of caspase-8 and its homologs

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Modifying effects of benzyl isothiocyanate and benzyl thiocyanate on DNA synthesis in primary cultures of rat hepatocytes.

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Mechanistic insights into chemopreventive effects of phenethyl isothiocyanate in N-nitrosobis(2-oxopropyl)amine-treated hamsters.

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Temporal effects of the detoxification enzyme inducer, benzyl isothiocyanate: activation of c-Jun N-terminal kinase prior to the transcription factors AP-1 and NFkappaB

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Effects of isothiocyanates on growth and metastaticity of B16-F10 melanoma cells

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Identifiers

10.1016/S0006-2952(00)00526-8

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

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