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A 21 point unifying hypothesis on the etiology and treatment of multiple sclerosis.
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9604129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9604129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
A 21 point unifying hypothesis on the etiology and treatment of multiple sclerosis
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9604129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9604129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
main subject
multiple sclerosis
0 references
unifying hypothesis
1 reference
based on heuristic
inferred from title
author name string
H L Weiner
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9604129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9604129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
publication date
1 May 1998
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9604129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9604129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
published in
Canadian Journal of Neurological Sciences
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9604129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9604129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
volume
25
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9604129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9604129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9604129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9604129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
page(s)
93-101
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9604129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9604129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
cites work
Immune deviation following pulse cyclophosphamide/methylprednisolone treatment of multiple sclerosis: Increased interleukin-4 production and associated eosinophilia
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reference URL
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7 January 2021
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Immunological aspects of experimental allergic encephalomyelitis and multiple sclerosis
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7 January 2021
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7 January 2021
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Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis
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Crossref
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7 January 2021
based on heuristic
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Interferon alpha-2a treatment of relapsing-remitting multiple sclerosis: disease activity resumes after stopping treatment
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Crossref
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7 January 2021
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Anti-myelin basic protein and anti-proteolipid protein specific forms of multiple sclerosis
1 reference
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reference URL
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7 January 2021
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Plasmapheresis in acute episodes of fulminant CNS inflammatory demyelination
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7 January 2021
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Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease
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7 January 2021
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Axonal transection in the lesions of multiple sclerosis
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Crossref
reference URL
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7 January 2021
based on heuristic
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Islet cell antigens in insulin-dependent diabetes: Pandora's box revisited
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Crossref
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7 January 2021
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Seasonal variation of multiple sclerosis exacerbations in Arizona.
1 reference
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Crossref
reference URL
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7 January 2021
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Mechanisms of recovery from experimental autoimmune encephalomyelitis: T cell deletion and immune deviation in myelin basic protein T cell receptor transgenic mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
based on heuristic
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Interferon beta induces interleukin-10 expression: relevance to multiple sclerosis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
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Randomised placebo-controlled trial of monthly intravenous immunoglobulin therapy in relapsing-remitting multiple sclerosis. Austrian Immunoglobulin in Multiple Sclerosis Study Group
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Crossref
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7 January 2021
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Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4,
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
based on heuristic
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A population-based study of multiple sclerosis in twins: update.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
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Correlating MRI and clinical disease activity in multiple sclerosis: relevance of hypointense lesions on short-TR/short-TE (T1-weighted) spin-echo images
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
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T cells responsive to myelin basic protein in patients with multiple sclerosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitative brain MRI lesion load predicts the course of clinically isolated syndromes suggestive of multiple sclerosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
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Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic control of multiple sclerosis: increased production of lymphotoxin and tumor necrosis factor-alpha by HLA-DR2+ T cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
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inferred from DOI database lookup
Reactivity to myelin antigens in multiple sclerosis. Peripheral blood lymphocytes respond predominantly to myelin oligodendrocyte glycoprotein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon beta augments suppressor cell function in multiple sclerosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
based on heuristic
inferred from DOI database lookup
Immunological aspects of demyelinating diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
based on heuristic
inferred from DOI database lookup
Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
based on heuristic
inferred from DOI database lookup
Autoreactive T lymphocytes in multiple sclerosis determined by antigen-induced secretion of interferon-gamma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of disease susceptibility: decreased prevalence of IgE-mediated allergic disease in patients with multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations in T cell antigen specificity and class II restriction during the course of chronic relapsing experimental allergic encephalomyelitis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunologic Mechanisms and Therapy in Multiple Sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Indictment of the microglia as the villain in multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Longitudinal MRI in multiple sclerosis: correlation between disability and lesion burden
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
based on heuristic
inferred from DOI database lookup
Antigen‐driven tissue‐specific suppression following oral tolerance: Orally administered myelin basic protein suppresses proteolipid protein‐induced experimental autoimmune encephalomyelitis in the SJL mouse
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
based on heuristic
inferred from DOI database lookup
Therapeutic effect of mitoxantrone combined with methylprednisolone in multiple sclerosis: a randomised multicentre study of active disease using MRI and clinical criteria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
based on heuristic
inferred from DOI database lookup
Development of reactivity to new myelin antigens during chronic relapsing autoimmune demyelination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Monoclonal anti-gamma interferon antibodies enhance experimental allergic encephalomyelitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exacerbations of multiple sclerosis in patients treated with gamma interferon
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Linomide reduces the rate of active lesions in relapsing-remitting multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Treatment of secondary progressive multiple sclerosis with the immunomodulator linomide: a double-blind, placebo-controlled pilot study with monthly magnetic resonance imaging evaluation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spinal cord atrophy and disability in multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overview of azathioprine treatment in multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppressor cell function in multiple sclerosis: Correlation with clinical disease activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A comparison of the pathology of primary and secondary progressive multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Therapy for multiple sclerosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of corticosteroids for acute optic neuritis on the subsequent development of multiple sclerosis. The Optic Neuritis Study Group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
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7 January 2021
based on heuristic
inferred from DOI database lookup
Oral tolerance: immune mechanisms and treatment of autoimmune diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-12 unmasks latent autoimmune disease in resistant mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oral insulin treatment suppresses virus-induced antigen-specific destruction of beta cells and prevents autoimmune diabetes in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunologic tolerance to myelin basic protein decreases stroke size after transient focal cerebral ischemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Copolymer 1 induces T cells of the T helper type 2 that crossreact with myelin basic protein and suppress experimental autoimmune encephalomyelitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of magnetic resonance techniques in understanding and managing multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pulse cyclophosphamide plus methylprednisolone induces myelin-antigen-specific IL-4-secreting T cells in multiple sclerosis patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo activated T lymphocytes in the peripheral blood and cerebrospinal fluid of patients with multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo labeling of blood T cells: rapid traffic into cerebrospinal fluid in multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of intensive immunosuppression on the course of chronic progressive multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy and toxicity of cyclosporine in chronic progressive multiple sclerosis: a randomized, double-blinded, placebo-controlled clinical trial. The Multiple Sclerosis Study Group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered Th1/Th2 balance associated with non-major histocompatibility complex genes in collagen-induced arthritis in resistant and non-resistant rat strains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligand
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Double-blind study of true vs. sham plasma exchange in patients treated with immunosuppression for acute attacks of multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. The Copolymer 1 Multiple Sclerosis Study Group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intermittent cyclophosphamide pulse therapy in progressive multiple sclerosis: final report of the Northeast Cooperative Multiple Sclerosis Treatment Group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphocyte responses and cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The treatment of chronic progressive multiple sclerosis with cladribine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gamma delta T-cell receptor repertoire in acute multiple sclerosis lesions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clonal expansions of activated gamma/delta T cells in recent-onset multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell tumor necrosis factor-alpha receptor binding in patients with multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low-dose (7.5 mg) oral methotrexate reduces the rate of progression in chronic progressive multiple sclerosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Dale E. McFarlin Memorial Lecture: the immunology of the multiple sclerosis lesion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct ex vivo analysis of activated, Fas-sensitive autoreactive T cells in human autoimmune disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased CD80(+) B cells in active multiple sclerosis and reversal by interferon beta-1b therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1017%2FS0317167100033680
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1017/S0317167100033680
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9604129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9604129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
PubMed publication ID
9604129
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9604129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9604129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
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