(Q32117245)

6 July 2017

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title

The pharmacokinetics of levosalbutamol: what are the clinical implications? (English)

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6 July 2017

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Boulton DW

1

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PubMed ID

11236808

6 July 2017

Fawcett JP

series ordinal

2

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6 July 2017

1 January 2001

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Clinical Pharmacokinetics

6 July 2017

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6 July 2017

40

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6 July 2017

23-40

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6 July 2017

1

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https://scigraph.springernature.com/pub.10.2165/00003088-200140010-00003

6 July 2017

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12 December 2020

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Inhaled beta-adrenergic receptor agonists in asthma: more harm than good?

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12 December 2020

Levosalbutamol: a viewpoint by Peter Black

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12 December 2020

Bronchoprotective and bronchodilator effects of single doses of (S)-salbutamol, (R)-salbutamol and racemic salbutamol in patients with bronchial asthma

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12 December 2020

International trends in asthma mortality: 1970 to 1985.

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Individual utilization of anti-asthma medication by young adults: a prescription database analysis.

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12 December 2020

Hep G2 cell line as a human model for sulphate conjugation of drugs

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12 December 2020

Tolerance to the bronchoprotective effect of beta2-agonists: comparison of the enantiomers of salbutamol with racemic salbutamol and placebo

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12 December 2020

Albuterol. A pharmaceutical chemistry review of R-, S-, and RS-albuterol

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12 December 2020

Gender differences in pharmacokinetics

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12 December 2020

Association between β2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitisation in moderately severe stable asthmatics

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12 December 2020

Pharmacokinetics and pharmacodynamics of single oral doses of albuterol and its enantiomers in humans

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12 December 2020

Resistance to -adrenoceptor stimulants (a possible explanation for the rise in ashtma deaths).

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12 December 2020

Enantioselective sulfation of beta 2-receptor agonists by the human intestine and the recombinant M-form phenolsulfotransferase

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12 December 2020

Stereoselective sulfate conjugation of 4-hydroxypropranolol and terbutaline by the human liver phenolsulfotransferases

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12 December 2020

Enantiomeric disposition of inhaled, intravenous and oral racemic-salbutamol in man--no evidence of enantioselective lung metabolism

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12 December 2020

Metabolic studies of salbutamol-3H: A new bronchodilator, in rat, rabbit, dog and man

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12 December 2020

Stereoselective sulphate conjugation of fenoterol by human phenolsulphotransferases

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12 December 2020

Association between genetic polymorphisms of the beta2-adrenoceptor and response to albuterol in children with and without a history of wheezing

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12 December 2020

Clinical pharmacokinetics of beta-agonists

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12 December 2020

Hyperresponsiveness of the airways following exposure of guinea-pigs to racemic mixtures and distomers of beta 2-selective sympathomimetics.

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12 December 2020

Nebulized salbutamol (albuterol): systemic absorption could be important in achieving bronchodilatation

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12 December 2020

The plasma protein binding of basic drugs

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12 December 2020

Enantioselective disposition of albuterol in humans

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12 December 2020

Stereoselective sulfation of albuterol in humans. Biosynthesis of the sulfate conjugate by HEP G2 cells.

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12 December 2020

Transdermal drug delivery systems of albuterol: in vitro and in vivo studies

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12 December 2020

Effect of single doses of S-salbutamol, R-salbutamol, racemic salbutamol, and placebo on the airway response to methacholine

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12 December 2020

Beta2-agonist enantiomers: is there a glitch with the chiral switch?

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12 December 2020

Molecular biology of the human phenol sulfotransferase gene family

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12 December 2020

Transfer of Salbutamol in the human placenta in vitro

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12 December 2020

Case-control study of prescribed fenoterol and death from asthma in New Zealand, 1977-81

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12 December 2020

Stereoselective sulphate conjugation of salbutamol by human lung and bronchial epithelial cells

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12 December 2020

Investigation into use of drugs preceding death from asthma

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12 December 2020

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12 December 2020

Perspectives in beta 2-agonist therapy: vox clamantis in deserto vel lux in tenebris?

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12 December 2020

Relative absorption of the two enantiomers of terbutaline after duodenal administration

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12 December 2020

Pharmacokinetics and absolute bioavailability of salbutamol in healthy adult volunteers

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12 December 2020

Levalbuterol nebulizer solution: is it worth five times the cost of albuterol?

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12 December 2020

Modification of Parkinsonism--chronic treatment with L-dopa

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12 December 2020

Absolute configuration of the optical isomers of salbutamol

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12 December 2020

Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate

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12 December 2020

Pharmacokinetics of intravenous and oral salbutamol and its sulphate conjugate

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12 December 2020

Stereoselective pharmacokinetics of S-salbutamol after administration of the racemate in healthy volunteers

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12 December 2020

A cohort analysis of excess mortality in asthma and the use of inhaled beta-agonists

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12 December 2020

Interindividual variability in the rate of salbutamol sulphation in the human lung.

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12 December 2020

Salbutamol in the 1980s. A reappraisal of its clinical efficacy

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12 December 2020

Determination of the enantiomers of salbutamol and its 4-O-sulphate metabolites in biological matrices by chiral liquid chromatography tandem mass spectrometry.

1 reference

12 December 2020

Competition for sulphate during detoxification in the gut wall

1 reference

12 December 2020

Stereoselective sulphate conjugation of salbutamol in humans: comparison of hepatic, intestinal and platelet activity.

1 reference

12 December 2020

Effects of S-salbutamol on human isolated bronchus

1 reference

12 December 2020

The metabolism of salbutamol in man.

1 reference

12 December 2020

Isolation and identification of the major metabolite of albuterol in human urine

1 reference

12 December 2020

Enantioselective disposition of salbutamol in man following oral and intravenous administration

1 reference

12 December 2020

Pharmacokinetic and pharmacodynamic characteristics and safety of inhaled albuterol enantiomers in healthy volunteers

1 reference

12 December 2020

Enantiomeric interaction in the sulfate conjugation of the beta 2-agonist drug albuterol by the human liver

1 reference

12 December 2020

Serum concentration and cardiovascular effects of salbutamol after oral and rectal administration in healthy volunteers

1 reference

12 December 2020

Effects of gender and race on albuterol pharmacokinetics

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12 December 2020

Stereoselective sulphate conjugation of racemic terbutaline by human liver cytosol

1 reference

12 December 2020

(+) and (-) terbutaline are sulphated at a higher rate in human intestine than in liver

1 reference

12 December 2020

Molecular mechanisms of membrane receptor desensitization.

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12 December 2020

Determination of the relative bioavailability of salbutamol to the lung following inhalation

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12 December 2020

Some observations on the -adrenoceptor agonist properties of the isomers of salbutamol

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12 December 2020

Stereoisomers and drug toxicity. The value of single stereoisomer therapy

1 reference

12 December 2020

Impact of genetic polymorphisms of the beta2-adrenergic receptor on albuterol bronchodilator pharmacodynamics.

1 reference

12 December 2020

Stereoselective sulfate conjugation of isoproterenol in humans: comparison of hepatic, intestinal, and platelet activity

1 reference

12 December 2020

Variability of fine particle deposition in healthy adults: effect of age and gender

1 reference

12 December 2020

Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance

1 reference

12 December 2020

The use of beta-agonists and the risk of death and near death from asthma

1 reference

12 December 2020

New Class of Selective Stimulants of β-Adrenergic Receptors

1 reference

12 December 2020

(S)-Albuterol increases intracellular free calcium by muscarinic receptor activation and a phospholipase C-dependent mechanism in airway smooth muscle.

1 reference

12 December 2020

Tachyphylaxis to systemic but not to airway responses during prolonged therapy with high dose inhaled salbutamol in asthmatics

1 reference

12 December 2020

The effect of beta-adrenoceptor agonists and antagonists on gastric emptying in man

1 reference

12 December 2020

Slow-release oral salbutamol and aminophylline in nocturnal asthma: relation of overnight changes in lung function and plasma drug levels

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12 December 2020

The beta-adrenoceptor

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12 December 2020

A comparison of salmeterol with albuterol in the treatment of mild-to-moderate asthma

1 reference

12 December 2020

Analysis of salbutamol enantiomers in human urine by chiral high-performance liquid chromatography and preliminary studies related to the stereoselective disposition kinetics in man

1 reference

12 December 2020

Effects of genetic polymorphism on ex vivo and in vivo function of beta2-adrenoceptors in asthmatic patients

1 reference

12 December 2020

Pharmacokinetics and extrapulmonary beta 2 adrenoceptor activity of nebulised racemic salbutamol and its R and S isomers in healthy volunteers

1 reference

12 December 2020

Asthma control during long-term treatment with regular inhaled salbutamol and salmeterol.

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of cumulative single doses of inhaled salbutamol enantiomers in asthmatic subjects

1 reference

12 December 2020

Pharmacokinetic/pharmacodynamic characteristics of the beta-2-agonists terbutaline, salbutamol and fenoterol

1 reference

12 December 2020

Beta2-adrenergic receptor polymorphisms affect airway responsiveness to salbutamol in asthmatics

1 reference

12 December 2020

Relative potency of (-)- and (+-)-salbutamol on guinea pig tracheal tissue

1 reference

12 December 2020

Mutations in the gene encoding for the beta 2-adrenergic receptor in normal and asthmatic subjects

1 reference

12 December 2020

Pharmacokinetic evaluation in man of terbutaline given as separate enantiomers and as the racemate

1 reference

12 December 2020

Prescribed fenoterol and death from asthma in New Zealand, 1981-83: case-control study

1 reference

12 December 2020

Transplacental distribution of salbutamol enantiomers at Caesarian section

1 reference

12 December 2020

Enantiomer specific pharmacokinetics

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12 December 2020

Renal tubule transport of organic cations

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12 December 2020

The human phenolsulphotransferase polymorphism is determined by the level of expression of the enzyme protein

1 reference

12 December 2020

Effects of airway calibre on lung delivery of nebulised salbutamol

1 reference

12 December 2020

Determination of salbutamol enantiomers in human plasma and urine by chiral high-performance liquid chromatography

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12 December 2020

Molecular geometry and adrenergic drug activity.

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12 December 2020

Salbutamol in the treatment of asthma

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12 December 2020

(-)-salbutamol sulphation in the human liver and duodenal mucosa: interindividual variability

1 reference

12 December 2020

Observations on recent increase in mortality from asthma

1 reference

12 December 2020

The safety and efficacy of nebulized levalbuterol compared with racemic albuterol and placebo in the treatment of asthma in pediatric patients

1 reference

12 December 2020

Preferential pulmonary retention of (S)-albuterol after inhalation of racemic albuterol

1 reference

12 December 2020

Stereoselective sulfation of terbutaline by the rat liver cytosol: evaluation of experimental approaches

1 reference

12 December 2020

X-ray crystal structure of human dopamine sulfotransferase, SULT1A3. Molecular modeling and quantitative structure-activity relationship analysis demonstrate a molecular basis for sulfotransferase substrate specificity

1 reference

12 December 2020

10.2165/00003088-200140010-00003

Identifiers

DOI

1 reference

PubMed ID

11236808

Dimensions Publication ID

6 July 2017

0 references

1 reference

PubMed ID

11236808