(Q32140159)

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Mitochondrial membrane potential and nuclear changes in apoptosis caused by serum and nerve growth factor withdrawal: time course and modification by (-)-deprenyl.

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 July 2017

Mitochondrial membrane potential and nuclear changes in apoptosis caused by serum and nerve growth factor withdrawal: time course and modification by (-)-deprenyl (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

apoptotic process

1 reference

based on heuristic

inferred from title

author name string

J S Wadia

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

R M Chalmers-Redman

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

W J Ju

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

G W Carlile

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

J L Phillips

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

A D Fraser

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

W G Tatton

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

language of work or name

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publication date

1 February 1998

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

18

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

932-947

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

mRNA expression of neurotrophins and members of the trk family in the rat brain after treatment with L-deprenyl

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opening of the mitochondrial permeability transition pore by uncoupling or inorganic phosphate in the presence of Ca2+ is dependent on mitochondrial-generated reactive oxygen species.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria: structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A fluorescence-microscopic and flow-cytometric study of HeLa cells with an experimentally induced respiratory deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apparent antioxidant effect of l-deprenyl on hydroxyl radical formation and nigral injury elicited by MPP+ in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contrasting monoamine oxidase activity and tyramine induced catecholamine release in PC12 and chromaffin cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific irreversible monoamine oxidase B inhibitors stimulate gene expression of aromatic L-amino acid decarboxylase in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal PC12 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidants in mitochondria: from physiology to diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of gene expression rather than monoamine oxidase inhibition: (-)-deprenyl-related compounds in controlling neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A critical evaluation of in situ measurement of mitochondrial electrical potentials in single hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased CNTF gene expression in process-bearing astrocytes following injury is augmented by R(-)-deprenyl

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of fluorescent probes to investigate the metabolic state of Pneumocystis carinii mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(-)Deprenyl increases the life span as well as activities of superoxide dismutase and catalase but not of glutathione peroxidase in selective brain regions in Fischer rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protein product of the oncogene bcl-2 is a component of the nuclear envelope, the endoplasmic reticulum, and the outer mitochondrial membrane.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial control of nuclear apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Striatal degeneration induced by mitochondrial blockade is prevented by biologically delivered NGF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of function of cytochrome c in Jurkat cells undergoing fas-mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial respiratory chain inhibitors induce apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pro-oxidants and mitochondrial Ca2+: their relationship to apoptosis and oncogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-function analysis of the Bcl-2 oncoprotein. Addition of a heterologous transmembrane domain to portions of the Bcl-2 beta protein restores function as a regulator of cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Mitochondrial Permeability Transition Pore is Modulated by Oxidative Agents Through Both Pyridine Nucleotides and Glutathione at Two Separate Sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor inhibits apoptosis induced by S-100 binding in neuronal PC12 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(-)-Deprenyl alters the time course of death of axotomized facial motoneurons and the hypertrophy of neighboring astrocytes in immature rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The participation of reactive oxygen species and protein thiols in the mechanism of mitochondrial inner membrane permeabilization by calcium plus prooxidants.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polarization of mitochondria in the unfertilized mouse oocyte

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acidic and basic fibroblast growth factors promote stable neurite outgrowth and neuronal differentiation in cultures of PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of MPTP and l‐Deprenyl on Antioxidant Enzymes and Lipid Peroxidation Levels in Mouse Brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial membrane potential in single living adult rat cardiac myocytes exposed to anoxia or metabolic inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(-)-Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial permeability transition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The concept of astrocyte-kinetic drug in the treatment of neurodegenerative diseases: evidence for L-deprenyl-induced activation of reactive astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in the Nervous System: Morphological Features, Methods, Pathology, and Prevention

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical evidence of neuroprotection by R(-)-deprenyl and N-(2-hexyl)-N-methylpropargylamine on DSP-4-induced degeneration of rat brain noradrenergic axons and terminals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selegiline enhances NGF synthesis and protects central nervous system neurons from excitotoxic and ischemic damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria, free radicals, and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial permeability transition triggers lymphocyte apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of cytochrome c from liver mitochondria during permeability transition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NGF, BDNF and NT-5, but not NT-3 protect against MPP+ toxicity and oxidative stress in neonatal animals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial permeability transition is a central coordinating event of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of estrogens on the proliferation of human breast tumor cells (MCF-7).

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Why are mitochondria involved in apoptosis? Permeability transition pores and apoptosis as selective mechanisms to eliminate superoxide-producing mitochondria and cell.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of BCL-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor-mediated cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selegiline is neuroprotective in primary brain cultures treated with 1-methyl-4-phenylpyridinium

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of apoptosis and DNA replication by differential labeling of DNA strand breaks with fluorochromes of different color

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The brain protein S-100ab induces apoptosis in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-deprenyl increases GFAP immunoreactivity selectively in activated astrocytes in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction in glial fibrillary acidic protein mRNA abundance induced by (-)-deprenyl and other monoamine oxidase B inhibitors in C6 glioma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of peripheral benzodiazepine receptors in the protection of hematopoietic cells against oxygen radical damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/9437015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.18-03-00932.1998

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792769&resulttype=core&format=json

12 May 2020

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