(Q33163663)

23 July 2017

title

New iPSC for old long QT syndrome modeling: putting the evidence into perspective (English)

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23 July 2017

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Guoliang Li

1

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23 July 2017

Gong Cheng

2

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23 July 2017

Jine Wu

3

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23 July 2017

Shuting Ma

4

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23 July 2017

Chaofeng Sun

5

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23 July 2017

publication date

20 December 2013

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Experimental Biology and Medicine

23 July 2017

published in

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23 July 2017

volume

239

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23 July 2017

issue

2

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23 July 2017

page(s)

131-140

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Expectations for the United Nations high-level meeting on noncommunicable diseases

23 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Genetics of human cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Clinical practice. Long-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Diseases in a dish: modeling human genetic disorders using induced pluripotent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Functional effects of mutations in KvLQT1 that cause long QT syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Mouse models of SCN5A-related cardiac arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Cardiomyocytes obtained from induced pluripotent stem cells with long-QT syndrome 3 recapitulate typical disease-specific features in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Embryonic stem cells as a source of models for drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

iPSCs and small molecules: a reciprocal effort towards better approaches for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Technical challenges in using human induced pluripotent stem cells to model disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Modelling the long QT syndrome with induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Induced pluripotent stem cells as a tool for gaining new insights into Fanconi anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

A comparison of murine smooth muscle cells generated from embryonic versus induced pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Generation of functional murine cardiac myocytes from induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Functional cardiomyocytes derived from human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Generation of induced pluripotent stem cells from human cord blood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Enhanced reprogramming and cardiac differentiation of human keratinocytes derived from plucked hair follicles, using a single excisable lentivirus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Patient-specific induced pluripotent stem-cell models for long-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Molecular characterization and functional properties of cardiomyocytes derived from human inducible pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Disease characterization using LQTS-specific induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

The genetic basis of long QT and short QT syndromes: a mutation update

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Biology of cardiac arrhythmias: ion channel protein trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Nonsense mutations in hERG cause a decrease in mutant mRNA transcripts by nonsense-mediated mRNA decay in human long-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Animal models for arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

The price of innovation: new estimates of drug development costs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Phase 0 clinical trials: an answer to drug development stagnation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Effects of torcetrapib in patients at high risk for coronary events

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

The failure of torcetrapib: what have we learned?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II Trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Neuropeptide Y5 receptor antagonism does not induce clinically meaningful weight loss in overweight and obese adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Can the pharmaceutical industry reduce attrition rates?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Opportunities for use of human iPS cells in predictive toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

The case for induced pluripotent stem cell-derived cardiomyocytes in pharmacological screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Probucol aggravates long QT syndrome associated with a novel missense mutation M124T in the N-terminus of HERG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

A common antitussive drug, clobutinol, precipitates the long QT syndrome 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Torsades de pointes complicating atrioventricular block: evidence for a genetic predisposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Cardiac safety pharmacology: from human ether-a-gogo related gene channel block towards induced pluripotent stem cell based disease models

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

The long QT syndrome. Prospective longitudinal study of 328 families

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

The idiopathic long QT syndrome: pathogenetic mechanisms and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Implantable cardioverter defibrillator therapy in children with long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Who are the long-QT syndrome patients who receive an implantable cardioverter-defibrillator and what happens to them?: data from the European Long-QT Syndrome Implantable Cardioverter-Defibrillator (LQTS ICD) Registry

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Induced pluripotent stem cells from a spinal muscular atrophy patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Phenotypic correction of murine hemophilia A using an iPS cell-based therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Induced pluripotent stem (iPS) cells repair and regenerate infarcted myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Future perspective of induced pluripotent stem cells for diagnosis, drug screening and treatment of human diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Chemical approaches to stem cell biology and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

Vascularized and functional human liver from an iPSC-derived organ bud transplant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1535370213514000

21 January 2018

Identifiers

DOI

10.1177/1535370213514000

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23 July 2017

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